Trilostane and its Impurities
Trilostane, sold under the brand names Modrenal and Vetoryl among others, is a medication which has been used in the treatment of Cushing's syndrome, Conn's syndrome, and postmenopausal breast cancer in humans. Reference standards of Trilostane API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(1S,3aS,3bR,10aR,10bS,12aS)-10a,12a-Dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
(1S,3aS,3bR,10aR,10bS,12aS)-10a,12a-Dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
Catalogue No.:PA 73 0511003
CAS :
60413-79-8
Molecular Formula : C20H27NO2
Molecular Weight : 313.44
(1S,3aS,3bS,5aS,6aS,10aR,10bS,12aS)-10a,12a-Dimethyl-1,2,3,3a,3b,4,5,6a,10,10a,10b,11,12,12a-tetradecahydrocyclopenta[7,8]oxireno[2',3':1,10a]phenanthro[3,2-d]isoxazol-1-ol
(1S,3aS,3bS,5aS,6aS,10aR,10bS,12aS)-10a,12a-Dimethyl-1,2,3,3a,3b,4,5,6a,10,10a,10b,11,12,12a-tetradecahydrocyclopenta[7,8]oxireno[2',3':1,10a]phenanthro[3,2-d]isoxazol-1-ol
Catalogue No.:PA 73 0511004
CAS :
20051-76-7
Molecular Formula : C20H27NO3
Molecular Weight : 329.44
(1S,3aS,3bS,5aS,6aS,10aR,10bS,12aS)-10a,12a-Dimethyl-1,2,3,3a,3b,4,5,6a,10,10a,10b,11,12,12a-tetradecahydrocyclopenta[7,8]oxireno[2',3':1,10a]phenanthro[3,2-d]isoxazol-1-yl acetate
(1S,3aS,3bS,5aS,6aS,10aR,10bS,12aS)-10a,12a-Dimethyl-1,2,3,3a,3b,4,5,6a,10,10a,10b,11,12,12a-tetradecahydrocyclopenta[7,8]oxireno[2',3':1,10a]phenanthro[3,2-d]isoxazol-1-yl acetate
Catalogue No.:PA 73 0511005
CAS :
13647-34-2
Molecular Formula : C22H29NO4
Molecular Weight : 371.48
