Upadacitinib, sold under the brand name Rinvoq, is a Janus kinase (JAK) inhibitor medication for the treatment of moderately to severely active rheumatoid arthritis in adults. where, its methotrexate a drug used to treat active arthritis. Reference standards of Upadacitinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Upadacitinib
Catalogue No.:PA 21 0180000
CAS :
Molecular Formula : C17H19F3N6O
Molecular Weight : 380.38
(3S,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181000
(3R,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181002
(3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181003
Molecular Formula : C24H25F3N6O3S
Molecular Weight : 534.56
Benzyl (3S,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate
Catalogue No.:PA 21 0181004
Molecular Formula : C16H21NO3
Molecular Weight : 275.35
Benzyl (3R,4S)-3-(2,2-dibromoacetyl)-4-ethylpyrrolidine-1-carboxylate
Catalogue No.:PA 21 0181005
Molecular Formula : C16H19Br2NO3
Molecular Weight : 433.14
8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine
Catalogue No.:PA 21 0181006
Molecular Formula : C14H17N5
Molecular Weight : 255.33
(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181007
rel-(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181008
(3S,4R)-3-Ethyl-4-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181009
Molecular Formula : C17H18F3N7O2
Molecular Weight : 409.37
(S)-N-Ethyl-3-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181010
Upadacitinib-15N-d2
Catalogue No.:PA STI 089629
Molecular Formula : C17H17D2F3N515NO
Molecular Weight : 383.38
Benzyl (3R,4S)-3-(2-chloroacetyl)-4-ethylpyrrolidine-1-carboxylate
Catalogue No.:PA 21 0181011
Molecular Formula : C16H20ClNO3
Molecular Weight : 309.79
(3S,4R)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
Catalogue No.:PA 21 0181012
Molecular Formula : C18H21F3N6O2
Molecular Weight : 410.4
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