Valbenazine and its Impurities
Valbenazine is used to treat symptoms of tardive dyskinesia, a nervous system disorder. It is sold under the trade name Ingrezza. Reference standards of Valbenazine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
L-Allothreonine, 3-methyl-, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester
L-Allothreonine, 3-methyl-, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester
Catalogue No.:PA 22 0811001
CAS :
2237934-70-0
Molecular Formula : C24H38N2O5
Molecular Weight : 434.58
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl D-valinate
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl D-valinate
Catalogue No.:PA 22 0811002
CAS :
1025504-59-9
Molecular Formula : C24H38N2O4
Molecular Weight : 418.58
(2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl D-valinate bis(4-methylbenzenesulfonate)
(2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl D-valinate bis(4-methylbenzenesulfonate)
Catalogue No.:PA 22 0811003
CAS :
NA
Molecular Formula : C38H54N2O10S2
Molecular Weight : 762.97
(2R,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
(2R,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
Catalogue No.:PA 22 0811004
CAS :
NA
Molecular Formula : C24H38N2O4
Molecular Weight : 418.58
(2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
(2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
Catalogue No.:PA 22 0811005
CAS :
NA
Molecular Formula : C24H38N2O4
Molecular Weight : 418.58
(2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
(2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate
Catalogue No.:PA 22 0811006
CAS :
NA
Molecular Formula : C24H38N2O4
Molecular Weight : 418.58
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl (tert-butoxycarbonyl)-L-valinate
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl (tert-butoxycarbonyl)-L-valinate
Catalogue No.:PA 22 0811007
CAS :
2102090-16-2
Molecular Formula : C29H46N2O6
Molecular Weight : 518.7
(2R,3R,11bR)-2-((L-Valyl)oxy)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydropyrido[2,1-a]isoquinoline 5(2H)-oxide
(2R,3R,11bR)-2-((L-Valyl)oxy)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydropyrido[2,1-a]isoquinoline 5(2H)-oxide
Catalogue No.:PA 22 0811008
CAS :
NA
Molecular Formula : C24H38N2O5
Molecular Weight : 434.58
