valganciclovir and its Impurities
Valganciclovir is used in adults to prevent infection with cytomegalovirus that may occur after an organ transplant. It is sold under the brandname Valcyte. Reference standards of Valganciclovir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(S)-4-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoic Acid
(S)-4-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoic Acid
Catalogue No.:PA 22 33570
CAS :
2518419-18-4
Molecular Formula : C24H30N6O8
Molecular Weight : 530.53
L-Valine 2-[[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]methoxy]-3-hydroxypropyl Ester
L-Valine 2-[[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]methoxy]-3-hydroxypropyl Ester
Catalogue No.:PA 22 33610
CAS :
1356932-88-1
Molecular Formula : C15H24N6O6
Molecular Weight : 384.39
D-Valganciclovir (2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-methoxy]-3-hydroxypropyl D-valine es (1708015)
D-Valganciclovir (2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-methoxy]-3-hydroxypropyl D-valine es (1708015)
Catalogue No.:PA USP1708015
CAS :
NA
Molecular Formula : NA
Molecular Weight : NA
(S)-1-((S)-3-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxypropoxy)-3-methyl-1-oxobutan-2-aminium Chloride
(S)-1-((S)-3-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxypropoxy)-3-methyl-1-oxobutan-2-aminium Chloride
Catalogue No.:PA 22 33630
CAS :
NA
Molecular Formula : C14H23ClN6O5
Molecular Weight : 390.83
(R)-2-((2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl L-Valinate compound with (S)-2-((2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl D-Valinate (1:1)
(R)-2-((2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl L-Valinate compound with (S)-2-((2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl D-Valinate (1:1)
Catalogue No.:PAI 22 003120
CAS :
NA
Molecular Formula : C15H22N6O6
Molecular Weight : 382.38
N-(9-(((1,4-Dioxaspiro[4.5]decan-2-yl)methoxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
N-(9-(((1,4-Dioxaspiro[4.5]decan-2-yl)methoxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
Catalogue No.:PAI 22 003070
CAS :
1807753-78-1
Molecular Formula : C17H23N5O5
Molecular Weight : 377.4
Valganciclovir
(R)-2-((2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl (tert-butoxycarbonyl)-L-valinate compound with (S)-2-((2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxyethyl (tert-butoxycarbonyl)-D-valinate (1:1)
Catalogue No.:PAI 22 003141
CAS :
NA
Molecular Formula : C40H60N12O16
Molecular Weight : 964.99
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl (2R,2'R)-bis(2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate)
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl (2R,2'R)-bis(2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate)
Catalogue No.:PAI 22 003142
CAS :
NA
Molecular Formula : C35H43N7O10
Molecular Weight : 721.77
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-D-valinate
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-D-valinate
Catalogue No.:PAI 22 003143
CAS :
NA
Molecular Formula : C22H28N6O7
Molecular Weight : 488.50
Ethyl (S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate
Ethyl (S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate
Catalogue No.:PAI 22 033001
CAS :
NA
Molecular Formula : C26H34N6O8
Molecular Weight : 558.59
(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-ethoxy-5-oxopentanoic Acid
(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-ethoxy-5-oxopentanoic Acid
Catalogue No.:PAI 22 033002
CAS :
1802552-09-5
Molecular Formula : C22H25N5O6
Molecular Weight : 455.47
2-((2-Amino-6-oxo-5,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-L-valyl-L-valinate
2-((2-Amino-6-oxo-5,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl ((benzyloxy)carbonyl)-L-valyl-L-valinate
Catalogue No.:PA 22 0781005
CAS :
1654737-34-4
Molecular Formula : C27H37N7O8
Molecular Weight : 587.63
2-Benzyloxycarbonylamino-3-methyl-butyric acid 2-(2-amino-6-oxo-5,6-dihydro- purin-9-ylmethoxy)-3-(2-benzyloxycarbonylamino-3-methyl-butyryloxy)-propyl Ester
2-Benzyloxycarbonylamino-3-methyl-butyric acid 2-(2-amino-6-oxo-5,6-dihydro- purin-9-ylmethoxy)-3-(2-benzyloxycarbonylamino-3-methyl-butyryloxy)-propyl Ester
Catalogue No.:PA 22 0781006
CAS :
NA
Molecular Formula : C35H43N7O10
Molecular Weight : 721.77
9,9'-(((2-Hydroxypropane-1,3-diyl)bis(oxy))bis(methylene))bis(2-amino-1,9-dihydro-6H-purin-6-one)
9,9'-(((2-Hydroxypropane-1,3-diyl)bis(oxy))bis(methylene))bis(2-amino-1,9-dihydro-6H-purin-6-one)
Catalogue No.:PA 22 0781007
CAS :
NA
Molecular Formula : C15H18N10O5
Molecular Weight : 418.37
3-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxypropyl valinate and 1-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropan-2-yl valinate, Hydrochloride (1:2)
3-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-2-hydroxypropyl valinate and 1-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropan-2-yl valinate, Hydrochloride (1:2)
Catalogue No.:PA 22 0781009
CAS :
NA
Molecular Formula : C14H24Cl2N6O5
Molecular Weight : 427.28
L-Valine 2-[[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]methoxy]-3-hydroxypropyl Ester Hydrochloride Salt
L-Valine 2-[[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]methoxy]-3-hydroxypropyl Ester Hydrochloride Salt
Catalogue No.:PA 22 0781010
CAS :
NA
Molecular Formula : C15H25ClN6O6
Molecular Weight : 420.85
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl N-methyl-N-nitroso-L-valinate
2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl N-methyl-N-nitroso-L-valinate
Catalogue No.:PA 22 0781012
CAS :
NA
Molecular Formula : C15H23N7O6
Molecular Weight : 397.39
