verapamil hydrochloride and its Impurities
Verapamil Hydrochloride is used in the treatment of high blood pressure, heart arrhythmias, and angina,16 and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a phenylalkylamine calcium channel blocker.Reference standards of Verapamil Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3-hydroxy-4-methoxyphenyl)-2-isopropylpentanenitrile
5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3-hydroxy-4-methoxyphenyl)-2-isopropylpentanenitrile
Catalogue No.:PA 22 0081005
CAS :
114847-42-6
Molecular Formula : C26H36N2O4
Molecular Weight : 440.58


5-((3,4-dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-(propan-2-yl-1,1,1,3,3,3-d6)pentanenitrile
5-((3,4-dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-(propan-2-yl-1,1,1,3,3,3-d6)pentanenitrile
Catalogue No.:PA STI 089965
CAS :
1329747-21-8
Molecular Formula : C26H30D6N2O4
Molecular Weight : 446.62