vincristine and its Impurities
Vincristine is used to treat leukemia, Hodgkin's disease, non-Hodgkin's lymphoma, rhabdomyosarcoma, neuroblastoma, and Wilms' tumor. Vincristine, also known as leurocristine and marketed under the brandname Oncovin. Reference standards of Vincristine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-acetoxy-3a-ethyl-9-((3S,7S,9S)-5-ethyl-9-(methoxycarbonyl)-2,4,7,8,9,10-hexahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
(3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-acetoxy-3a-ethyl-9-((3S,7S,9S)-5-ethyl-9-(methoxycarbonyl)-2,4,7,8,9,10-hexahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
Catalogue No.:PAI 22 005010
CAS :
NA
Molecular Formula : C46H54N4O9
Molecular Weight : 806.94
(4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-(5-ethyl-9-(methoxycarbonyl)-2,4,7,8,9,10-hexahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-3a1,5a,6,8-tetramethyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
(4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-(5-ethyl-9-(methoxycarbonyl)-2,4,7,8,9,10-hexahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-3a1,5a,6,8-tetramethyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
Catalogue No.:PAI 22 005020
CAS :
NA
Molecular Formula : C48H60N4O7
Molecular Weight : 805.01
