Zanubrutinib, sold under the brand name Brukinsa, is for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Reference standards of Zanubrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(S)-7-(1-Acryloylpiperidin-4-yl)-4-nitroso-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
Catalogue No.:PA 26 0391000
CAS :
Molecular Formula : C27H28N6O4
Molecular Weight : 500.56
Zanubrutinib
Catalogue No.:PA 26 0390000
Molecular Formula : C27H29N5O3
Molecular Weight : 471.56
Zanubrutinib R-Isomer
Catalogue No.:PA 26 0391001
(S)-7-(1-(3-Chloropropanoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
Catalogue No.:PA 26 0391002
Molecular Formula : C27H30ClN5O3
Molecular Weight : 508.02
(S)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
Catalogue No.:PA 26 0391003
Molecular Formula : C27H27N5O2
Molecular Weight : 453.55
5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Catalogue No.:PA 26 0391004
Molecular Formula : C16H12N4O
Molecular Weight : 276.3
3-(4-(3-Carbamoyl-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl)propanoic Acid
Catalogue No.:PA 26 0391005
Molecular Formula : C27H31N5O4
Molecular Weight : 489.58
2-(4-Phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
Catalogue No.:PA 26 0391006
Molecular Formula : C23H26N4O
Molecular Weight : 374.49
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