pyrimethamine
Used for the treatment of toxoplasmosis ( a parasitic disease) and cystoisosporiasis (human intestinal parasitic disease ) in combination with leucovorin. It works by inhibiting the synthesis of RNA and DNA in many species. A dihydrofolate reductase inhibitor.Reference standards of Pyrimethamine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Pyrimethamine (IPRS/53/14)-from IPC
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Pyrimethamine (IPRS/54/20)
