afatinib
Nitrosamine Standards
- afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif. Reference standards of Afatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => (S,E)-N-(4-((3-Chloro-4-fluorophenyl)(nitroso)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
[catalogue_number] => PA 28 0021014
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 514.94
[form] => C24H24ClFN6O4
[cas] => NA
[pslug] => s-e-n-4-3-chloro-4-fluorophenyl-nitroso-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa280021014
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(S,E)-N-(4-((3-Chloro-4-fluorophenyl)(nitroso)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Catalogue No.:PA 28 0021014
Molecular Formula : C24H24ClFN6O4
Molecular Weight : 514.94
stdClass Object
(
[pname] => (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide
[catalogue_number] => PA 28 0021031
[category_ids] => ,79,69,71,78,70,82,162,
[chemical_name] =>
[weight] => 500.92
[form] => C23H22ClFN6O4
[cas] => NA
[pslug] => s-e-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-methyl-nitroso-amino-but-2-enamide-pa280021031
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(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide
Catalogue No.:PA 28 0021031
Molecular Formula : C23H22ClFN6O4
Molecular Weight : 500.92
