apixaban

Nitrosamine Standards - Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate
    [catalogue_number] => PA 28 0111046
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 285.68
    [form] => C11H12ClN3O4
    [cas] => NA
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PA 28 0111046
PA 28 0111046

Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate

  • Catalogue No.:PA 28 0111046

  • CAS :

    NA

  • Molecular Formula : C11H12ClN3O4

  • Molecular Weight : 285.68

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stdClass Object
(
    [pname] => Ethyl 6-(4-(5-chloro-N-nitrosopentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111047
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 554
    [form] => C27H28ClN5O6
    [cas] => NA
    [pslug] => ethyl-6-4-5-chloro-n-nitrosopentanamido-phenyl-1-4-methoxyphenyl-7-oxo-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111047
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PA 28 0111047
PA 28 0111047

Ethyl 6-(4-(5-chloro-N-nitrosopentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111047

  • CAS :

    NA

  • Molecular Formula : C27H28ClN5O6

  • Molecular Weight : 554

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Details 
stdClass Object
(
    [pname] => N-Nitroso Apixaban Amino Acid Impurity
    [catalogue_number] => PA 28 0111049
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 506.52
    [form] => C25H26N6O6
    [cas] => NA
    [pslug] => n-nitroso-apixaban-amino-acid-impurity-pa280111049
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PA 28 0111049
PA 28 0111049

N-Nitroso Apixaban Amino Acid Impurity

  • Catalogue No.:PA 28 0111049

  • CAS :

    NA

  • Molecular Formula : C25H26N6O6

  • Molecular Weight : 506.52

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Details 
stdClass Object
(
    [pname] => 6-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosohexanamide
    [catalogue_number] => PA 28 0111050
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 434.92
    [form] => C21H27ClN4O4
    [cas] => NA
    [pslug] => 6-chloro-n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-n-nitrosohexanamide-pa280111050
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PA 28 0111050
PA 28 0111050

6-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosohexanamide

  • Catalogue No.:PA 28 0111050

  • CAS :

    NA

  • Molecular Formula : C21H27ClN4O4

  • Molecular Weight : 434.92

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Details 
stdClass Object
(
    [pname] => 6-(4-((5-Amino-5-oxopentyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
    [catalogue_number] => PA 28 0111058
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 505.54
    [form] => C25H27N7O5
    [cas] => NA
    [pslug] => 6-4-5-amino-5-oxopentyl-nitroso-amino-phenyl-1-4-methoxyphenyl-7-oxo-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxamide-pa280111058
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PA 28 0111058
PA 28 0111058

6-(4-((5-Amino-5-oxopentyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111058

  • CAS :

    NA

  • Molecular Formula : C25H27N7O5

  • Molecular Weight : 505.54

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Details 
stdClass Object
(
    [pname] => 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylic Acid
    [catalogue_number] => PA 28 0111059
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 506.52
    [form] => C25H26N6O6
    [cas] => NA
    [pslug] => 3-carbamoyl-1-4-methoxyphenyl-4-2-nitroso-4-2-oxopiperidin-1-yl-phenyl-amino-ethyl-1h-pyrazole-5-carboxylic-acid-pa280111059
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PA 28 0111059
PA 28 0111059

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylic Acid

  • Catalogue No.:PA 28 0111059

  • CAS :

    NA

  • Molecular Formula : C25H26N6O6

  • Molecular Weight : 506.52

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Details 
stdClass Object
(
    [pname] => 5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide
    [catalogue_number] => PA 28 0111068
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 420.89
    [form] => C20H25ClN4O4
    [cas] => NA
    [pslug] => 5-chloro-n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-n-nitrosopentanamide-pa280111068
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PA 28 0111068
PA 28 0111068

5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide

  • Catalogue No.:PA 28 0111068

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

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Details 
stdClass Object
(
    [pname] => 6-(4-((4-Carboxybutyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
    [catalogue_number] => PA 28 0111078
    [category_ids] => ,78,70,82,162,
    [chemical_name] => 
    [weight] => 507.5
    [form] => C25H25N5O7
    [cas] => NA
    [pslug] => 6-4-4-carboxybutyl-nitroso-amino-phenyl-1-4-methoxyphenyl-7-oxo-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylic-acid-pa280111078
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PA 28 0111078
PA 28 0111078

6-(4-((4-Carboxybutyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

  • Catalogue No.:PA 28 0111078

  • CAS :

    NA

  • Molecular Formula : C25H25N5O7

  • Molecular Weight : 507.5

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Details 
stdClass Object
(
    [pname] => 5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)amino)pentanoic Acid
    [catalogue_number] => PA 28 0111079
    [category_ids] => ,78,70,82,162,
    [chemical_name] => 
    [weight] => 373.45
    [form] => C20H27N3O4
    [cas] => NA
    [pslug] => 5-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-amino-pentanoic-acid-pa280111079
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PA 28 0111079
PA 28 0111079

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)amino)pentanoic Acid

  • Catalogue No.:PA 28 0111079

  • CAS :

    NA

  • Molecular Formula : C20H27N3O4

  • Molecular Weight : 373.45

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Details 
stdClass Object
(
    [pname] => 3-Morpholino-1-(3-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
    [catalogue_number] => PA 28 0111087
    [category_ids] => ,78,70,82,162,
    [chemical_name] => 
    [weight] => 303.32
    [form] => C15H17N3O4
    [cas] => 2443747-50-8
    [pslug] => 2443747-50-8-3-morpholino-1-3-nitrophenyl-5-6-dihydropyridin-2-1h-one-pa280111087
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PA 28 0111087
PA 28 0111087

3-Morpholino-1-(3-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111087

  • CAS :

    2443747-50-8

  • Molecular Formula : C15H17N3O4

  • Molecular Weight : 303.32

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