bosutinib

Nitrosamine Standards - Bosutinib is used to treat chronic myeloid leukaemia that has an abnormal chromosome called the Philadelphia chromosome. It is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.. Reference standards of Bosutinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile
    [catalogue_number] => PA 02 0921030
    [category_ids] => ,70,71,78,80,81,82,162,
    [chemical_name] => 
    [weight] => 545.42
    [form] => C25H26Cl2N6O4
    [cas] => NA
    [pslug] => 4-2-4-dichloro-5-methoxyphenyl-amino-6-methoxy-7-3-4-nitrosopiperazin-1-yl-propoxy-quinoline-3-carbonitrile-pa020921030
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PA 02 0921030
PA 02 0921030

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921030

  • CAS :

    NA

  • Molecular Formula : C25H26Cl2N6O4

  • Molecular Weight : 545.42

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Details 
stdClass Object
(
    [pname] => 1-(3-(2-Methoxy-5-nitrophenoxy)propyl)-4-nitrosopiperazine
    [catalogue_number] => PA 02 0921033
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 324.34
    [form] => C14H20N4O5
    [cas] => NA
    [pslug] => 1-3-2-methoxy-5-nitrophenoxy-propyl-4-nitrosopiperazine-pa020921033
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PA 02 0921033
PA 02 0921033

1-(3-(2-Methoxy-5-nitrophenoxy)propyl)-4-nitrosopiperazine

  • Catalogue No.:PA 02 0921033

  • CAS :

    NA

  • Molecular Formula : C14H20N4O5

  • Molecular Weight : 324.34

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Details 
stdClass Object
(
    [pname] => 2-Cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-((4-methoxy-3-(3-(4-nitrosopiperazin-1-yl)propoxy)phenyl)amino)acrylamide
    [catalogue_number] => PA 02 0921034
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 563.44
    [form] => C25H28Cl2N6O5
    [cas] => NA
    [pslug] => 2-cyano-n-2-4-dichloro-5-methoxyphenyl-3-4-methoxy-3-3-4-nitrosopiperazin-1-yl-propoxy-phenyl-amino-acrylamide-pa020921034
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PA 02 0921034
PA 02 0921034

2-Cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-((4-methoxy-3-(3-(4-nitrosopiperazin-1-yl)propoxy)phenyl)amino)acrylamide

  • Catalogue No.:PA 02 0921034

  • CAS :

    NA

  • Molecular Formula : C25H28Cl2N6O5

  • Molecular Weight : 563.44

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Details 
stdClass Object
(
    [pname] => N-(3-Cyano-6-methoxy-7-propoxyquinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide
    [catalogue_number] => PA 02 0921035
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 461.3
    [form] => C21H18Cl2N4O4
    [cas] => NA
    [pslug] => n-3-cyano-6-methoxy-7-propoxyquinolin-4-yl-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921035
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PA 02 0921035
PA 02 0921035

N-(3-Cyano-6-methoxy-7-propoxyquinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

  • Catalogue No.:PA 02 0921035

  • CAS :

    NA

  • Molecular Formula : C21H18Cl2N4O4

  • Molecular Weight : 461.3

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Details 
stdClass Object
(
    [pname] => N,N'-((Propane-1,3-diylbis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)
    [catalogue_number] => PA 02 0921036
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 878.5
    [form] => C39H28Cl4N8O8
    [cas] => NA
    [pslug] => n-n-propane-1-3-diylbis-oxy-bis-3-cyano-6-methoxyquinoline-7-4-diyl-bis-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921036
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PA 02 0921036
PA 02 0921036

N,N'-((Propane-1,3-diylbis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

  • Catalogue No.:PA 02 0921036

  • CAS :

    NA

  • Molecular Formula : C39H28Cl4N8O8

  • Molecular Weight : 878.5

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Details 
stdClass Object
(
    [pname] => N,N'-(((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)
    [catalogue_number] => PA 02 0921037
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 1004.7
    [form] => C46H42Cl4N10O8
    [cas] => NA
    [pslug] => n-n-piperazine-1-4-diylbis-propane-3-1-diyl-bis-oxy-bis-3-cyano-6-methoxyquinoline-7-4-diyl-bis-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921037
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PA 02 0921037
PA 02 0921037

N,N'-(((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

  • Catalogue No.:PA 02 0921037

  • CAS :

    NA

  • Molecular Formula : C46H42Cl4N10O8

  • Molecular Weight : 1004.7

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Details 
stdClass Object
(
    [pname] => N-(3-Cyano-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide
    [catalogue_number] => PA 02 0921038
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 559.45
    [form] => C26H28Cl2N6O4
    [cas] => NA
    [pslug] => n-3-cyano-6-methoxy-7-3-4-methylpiperazin-1-yl-propoxy-quinolin-4-yl-n-2-4-dichloro-5-methoxyphenyl-nitrous-amide-pa020921038
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PA 02 0921038
PA 02 0921038

N-(3-Cyano-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

  • Catalogue No.:PA 02 0921038

  • CAS :

    NA

  • Molecular Formula : C26H28Cl2N6O4

  • Molecular Weight : 559.45

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