eltrombopag
Nitrosamine Standards
- Eltrombopag is used to treat low blood platelet counts in adults with chronic immune thrombocytopenia when certain other medicines, or surgery to remove the spleen, have not worked well enough. It has been recently approved for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.. Reference standards of Eltrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[pname] => (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
[catalogue_number] => PA 32 0221000
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[chemical_name] =>
[weight] => 471.47
[form] => C25H21N5O5
[cas] => NA
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(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.:PA 32 0221000
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
stdClass Object
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[pname] => N-Nitroso Eltrombopag Amino Impurity
[catalogue_number] => PA 32 0221013
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[chemical_name] =>
[weight] => 258.23
[form] => C13H10N2O4
[cas] => NA
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N-Nitroso Eltrombopag Amino Impurity
Catalogue No.:PA 32 0221013
Molecular Formula : C13H10N2O4
Molecular Weight : 258.23
stdClass Object
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[pname] => 2-(3,4-Dimethylphenyl)-5-methyl-1-nitroso-1,2-dihydro-3H-pyrazol-3-one
[catalogue_number] => PA 32 0221019
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[chemical_name] =>
[weight] => 231.26
[form] => C12H13N3O2
[cas] => NA
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2-(3,4-Dimethylphenyl)-5-methyl-1-nitroso-1,2-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221019
Molecular Formula : C12H13N3O2
Molecular Weight : 231.26
stdClass Object
(
[pname] => Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
[catalogue_number] => PA 32 0221026
[category_ids] => ,103,80,71,78,70,82,162,
[chemical_name] =>
[weight] => 485.5
[form] => C26H23N5O5
[cas] => NA
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Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
stdClass Object
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[pname] => (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 0221027
[category_ids] => ,70,71,78,80,82,103,162,
[chemical_name] =>
[weight] => 471.47
[form] => C25H21N5O5
[cas] => NA
[pslug] => z-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-hydrazinyl-2-hydroxy-5-nitroso-1-1-biphenyl-3-carboxylic-acid-pa320221027
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(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221027
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
stdClass Object
(
[pname] => 2'-Hydroxy-3'-(1-nitrosohydrazineyl)-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 0221029
[category_ids] => ,78,70,82,162,
[chemical_name] =>
[weight] => 273.25
[form] => C13H11N3O4
[cas] => NA
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2'-Hydroxy-3'-(1-nitrosohydrazineyl)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221029
Molecular Formula : C13H11N3O4
Molecular Weight : 273.25
stdClass Object
(
[pname] => 2'-Hydroxy-3'-(methyl(nitroso)amino)-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 0221040
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[chemical_name] =>
[weight] => 272.26
[form] => C14H12N2O4
[cas] => NA
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2'-Hydroxy-3'-(methyl(nitroso)amino)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221040
Molecular Formula : C14H12N2O4
Molecular Weight : 272.26
