ibrutinib
Ibrutinib is used to treat chronic lymphocytic leukemia Waldenström's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease. It is a small molecule drug. Reference standards of Ibrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[form] => C22H21N7O2
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1-(1-Nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Catalogue No.:PA 09 0271021
Molecular Formula : C22H21N7O2
Molecular Weight : 415.46
stdClass Object
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(R)-1-(1-Nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Catalogue No.:PA 09 0271027
Molecular Formula : C22H21N7O2
Molecular Weight : 415.46
stdClass Object
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[pname] => N-(1-((R)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(3-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)nitrous amide
[catalogue_number] => PA 09 0271052
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[weight] => 910.01
[form] => C50H47N13O5
[cas] => NA
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N-(1-((R)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(3-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)nitrous amide
Catalogue No.:PA 09 0271052
Molecular Formula : C50H47N13O5
Molecular Weight : 910.01
stdClass Object
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[pname] => ((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)(1-((R)-1-nitrosopiperidin-3-yl)-2a-(4-phenoxyphenyl)-1,2,2a,3,4,5-hexahydro-1,2,5,6,8-pentaazaacenaphthylen-4-yl)methanone
[catalogue_number] => PA 09 0271055
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[weight] => 855.96
[form] => C47H45N13O4
[cas] => NA
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((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)(1-((R)-1-nitrosopiperidin-3-yl)-2a-(4-phenoxyphenyl)-1,2,2a,3,4,5-hexahydro-1,2,5,6,8-pentaazaacenaphthylen-4-yl)methanone
Catalogue No.:PA 09 0271055
Molecular Formula : C47H45N13O4
Molecular Weight : 855.96
