ivacaftor
Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => 1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
[catalogue_number] => PA 09 0401005
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 218.17
[form] => C10H6N2O4
[cas] => NA
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1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
Catalogue No.:PA 09 0401005
Molecular Formula : C10H6N2O4
Molecular Weight : 218.17
stdClass Object
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[pname] => N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401007
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 365.39
[form] => C20H19N3O4
[cas] => NA
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N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide
Catalogue No.:PA 09 0401007
Molecular Formula : C20H19N3O4
Molecular Weight : 365.39
stdClass Object
(
[pname] => Ivacaftor Nitroso Impurity
[catalogue_number] => PA 09 0401008
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
[cas] => NA
[pslug] => ivacaftor-nitroso-impurity-pa090401008
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Ivacaftor Nitroso Impurity
stdClass Object
(
[pname] => N-Nitroso Ivacaftor Ortho Isomer
[catalogue_number] => PA 09 0401010
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
[cas] => NA
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N-Nitroso Ivacaftor Ortho Isomer
stdClass Object
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[pname] => Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate
[catalogue_number] => PA 09 0401011
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 246.22
[form] => C12H10N2O4
[cas] => NA
[pslug] => ethyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylate-pa090401011
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Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate
Catalogue No.:PA 09 0401011
Molecular Formula : C12H10N2O4
Molecular Weight : 246.22
stdClass Object
(
[pname] => Diethyl 2-((nitroso(phenyl)amino)methylene)malonate
[catalogue_number] => PA 09 0401013
[category_ids] => ,78,70,82,162,
[chemical_name] =>
[weight] => 292.29
[form] => C14H16N2O5
[cas] => NA
[pslug] => diethyl-2-nitroso-phenyl-amino-methylene-malonate-pa090401013
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Diethyl 2-((nitroso(phenyl)amino)methylene)malonate
Catalogue No.:PA 09 0401013
Molecular Formula : C14H16N2O5
Molecular Weight : 292.29
stdClass Object
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[pname] => N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401014
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
[cas] => NA
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N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide