nilotinib
Nitrosamine Standards
- Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
[catalogue_number] => PA 14 0641020
[category_ids] => ,162,82,78,76,75,70,
[chemical_name] =>
[weight] => 558.53
[form] => C28H21F3N8O2
[cas] => 2925306-68-7
[pslug] => 2925306-68-7-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-3-nitroso-4-pyridin-3-yl-pyrimidin-2-yl-amino-benzamide-pa140641020
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4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 0641020
Molecular Formula : C28H21F3N8O2
Molecular Weight : 558.53
stdClass Object
(
[pname] => 4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic Acid
[catalogue_number] => PA 14 0641026
[category_ids] => ,70,78,82,162,
[chemical_name] =>
[weight] => 335.32
[form] => C17H13N5O3
[cas] => NA
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4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic Acid
Catalogue No.:PA 14 0641026
Molecular Formula : C17H13N5O3
Molecular Weight : 335.32
stdClass Object
(
[pname] => N-(3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
[catalogue_number] => PA 14 0641027
[category_ids] => ,70,78,82,162,
[chemical_name] =>
[weight] => 580.96
[form] => C27H20ClF3N8O2
[cas] => NA
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N-(3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
Catalogue No.:PA 14 0641027
Molecular Formula : C27H20ClF3N8O2
Molecular Weight : 580.96
stdClass Object
(
[pname] => 3-(2-((2-Methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(nitroso)amino)pyrimidin-4-yl)pyridine 1-oxide
[catalogue_number] => PA 14 0641030
[category_ids] => ,75,76,78,82,162,
[chemical_name] =>
[weight] => 574.52
[form] => C28H21F3N8O3
[cas] => NA
[pslug] => 3-2-2-methyl-5-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-carbamoyl-phenyl-nitroso-amino-pyrimidin-4-yl-pyridine-1-oxide-pa140641030
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3-(2-((2-Methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(nitroso)amino)pyrimidin-4-yl)pyridine 1-oxide
Catalogue No.:PA 14 0641030
Molecular Formula : C28H21F3N8O3
Molecular Weight : 574.52
stdClass Object
(
[pname] => Methyl 4-methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
[catalogue_number] => PA 14 0641045
[category_ids] => ,85,83,78,70,82,162,
[chemical_name] =>
[weight] => 349.35
[form] => C18H15N5O3
[cas] => NA
[pslug] => methyl-4-methyl-3-nitroso-4-pyridin-3-yl-pyrimidin-2-yl-amino-benzoate-pa140641045
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Methyl 4-methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
Catalogue No.:PA 14 0641045
Molecular Formula : C18H15N5O3
Molecular Weight : 349.35
