sacubitril
An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => N-Nitroso Sacubitril
[catalogue_number] => PA 19 0661036
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[chemical_name] =>
[weight] => 440.5
[form] => C24H28N2O6
[cas] => NA
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stdClass Object
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[pname] => 5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-1-nitrosopyrrolidin-2-one
[catalogue_number] => PA 19 0661055
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[chemical_name] =>
[weight] => 294.35
[form] => C18H18N2O2
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5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-1-nitrosopyrrolidin-2-one
Catalogue No.:PA 19 0661055
Molecular Formula : C18H18N2O2
Molecular Weight : 294.35
stdClass Object
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[pname] => (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxy-N-nitrosopropanamido)-2-methylpentanoic Acid
[catalogue_number] => PA 19 0661062
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[chemical_name] =>
[weight] => 412.44
[form] => C22H24N2O6
[cas] => NA
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(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxy-N-nitrosopropanamido)-2-methylpentanoic Acid
Catalogue No.:PA 19 0661062
Molecular Formula : C22H24N2O6
Molecular Weight : 412.44
stdClass Object
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[pname] => (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)(nitroso)amino)-2-methylpentanoic Acid
[catalogue_number] => PA 19 0661063
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[weight] => 412.49
[form] => C23H28N2O5
[cas] => NA
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(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)(nitroso)amino)-2-methylpentanoic Acid
Catalogue No.:PA 19 0661063
Molecular Formula : C23H28N2O5
Molecular Weight : 412.49