astemizole
Astemizole is rapidly absorbed from the gastrointestinal tract and competitively binds to histamine H1 receptor sites in the gastrointestinal tract, uterus, blood vessels, and bronchial muscle. It is a histamine H1-receptor antagonist. It has anticholinergic and antipruritic effects.. Reference standards of Astemizole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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