eltrombopag
Eltrombopag is used to treat low blood platelet counts in adults with chronic immune thrombocytopenia when certain other medicines, or surgery to remove the spleen, have not worked well enough. It has been recently approved for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.. Reference standards of Eltrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
(
[pname] => Eltrombopag
[catalogue_number] => PA 32 22000
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 442.47
[form] => C25H22N4O4
[cas] => 496775-61-2
[pslug] => 496775-61-2-eltrombopag-api-pa3222000
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Catalogue No.:PA 32 22000
Molecular Formula : C25H22N4O4
Molecular Weight : 442.47
stdClass Object
(
[pname] => Eltrombopag Amide
[catalogue_number] => PA 32 22510
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[chemical_name] =>
[weight] => 441.48
[form] => C25H23N5O3
[cas] => 1246929-02-1
[pslug] => 1246929-02-1-eltrombopag-amide-pa3222510
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Catalogue No.:PA 32 22510
Molecular Formula : C25H23N5O3
Molecular Weight : 441.48
stdClass Object
(
[pname] => Eltrombopag Ethyl Ester
[catalogue_number] => PA 32 22520
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 470.52
[form] => C27H26N4O4
[cas] => NA
[pslug] => eltrombopag-ethyl-ester-pa3222520
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Catalogue No.:PA 32 22520
Molecular Formula : C27H26N4O4
Molecular Weight : 470.52
stdClass Object
(
[pname] => Eltrombopag Methyl Ester
[catalogue_number] => PA 32 22530
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 456.49
[form] => C26H24N4O4
[cas] => 1246929-01-0
[pslug] => 1246929-01-0-eltrombopag-methyl-ester-pa3222530
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Catalogue No.:PA 32 22530
Molecular Formula : C26H24N4O4
Molecular Weight : 456.49
stdClass Object
(
[pname] => (E)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 22540
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 492.91
[form] => C25H21ClN4O5
[cas] => NA
[pslug] => e-5-chloro-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1h-pyrazol-4-5h-ylidene-1-hydroxyhydrazinyl-2-hydroxy-1-1-biphenyl-3-carboxylic-acid-pa3222540
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(E)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22540
Molecular Formula : C25H21ClN4O5
Molecular Weight : 492.91
stdClass Object
(
[pname] => 1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one
[catalogue_number] => PA 32 22550
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 365.38
[form] => C21H19NO5
[cas] => 1201816-68-3
[pslug] => 1201816-68-3-1-4-ethoxyphenyl-5-2-hydroxy-4-methoxybenzoyl-pyridin-2-1h-one-pa3222550
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1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one
Catalogue No.:PA 32 22550
Molecular Formula : C21H19NO5
Molecular Weight : 365.38
stdClass Object
(
[pname] => (E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 22560
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 456.49
[form] => C26H24N4O4
[cas] => NA
[pslug] => e-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1h-pyrazol-4-5h-ylidene-hydrazinyl-2-methoxy-1-1-biphenyl-3-carboxylic-acid-pa3222560
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(E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22560
Molecular Formula : C26H24N4O4
Molecular Weight : 456.49
stdClass Object
(
[pname] => (Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 22580
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 532.59
[form] => C32H28N4O4
[cas] => NA
[pslug] => z-2-benzyloxy-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1h-pyrazol-4-5h-ylidene-hydrazinyl-1-1-biphenyl-3-carboxylic-acid-pa3222580
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(Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22580
Molecular Formula : C32H28N4O4
Molecular Weight : 532.59
stdClass Object
(
[pname] => Eltrombopag-13C4
[catalogue_number] => PA STI 036900
[category_ids] => ,103,80,71,78,70,82,98,
[chemical_name] =>
[weight] => 446.44
[form] => C2113C4H22N4O4
[cas] => 1217230-31-3
[pslug] => 1217230-31-3-eltrombopag-13c4-pasti036900
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Catalogue No.:PA STI 036900
Molecular Formula : C2113C4H22N4O4
Molecular Weight : 446.44
stdClass Object
(
[pname] => (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
[catalogue_number] => PA 32 0221000
[category_ids] => ,70,71,78,80,82,103,162,
[chemical_name] =>
[weight] => 471.47
[form] => C25H21N5O5
[cas] => NA
[pslug] => -z-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-1-nitrosohydrazinyl-2-hydroxy-1-1-biphenyl-3-carboxylic-acid-pa320221000
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(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.:PA 32 0221000
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
stdClass Object
(
[pname] => N-Nitroso Eltrombopag Amino Impurity
[catalogue_number] => PA 32 0221013
[category_ids] => ,70,71,78,80,82,103,162,
[chemical_name] =>
[weight] => 258.23
[form] => C13H10N2O4
[cas] => NA
[pslug] => n-nitroso-eltrombopag-amino-impurity-pa320221013
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N-Nitroso Eltrombopag Amino Impurity
Catalogue No.:PA 32 0221013
Molecular Formula : C13H10N2O4
Molecular Weight : 258.23
stdClass Object
(
[pname] => Eltrombopag dimer-1 impurity
[catalogue_number] => PA 32 0221018
[category_ids] => ,103,80,71,78,82,
[chemical_name] =>
[weight] => 910
[form] => C52H47N9O7
[cas] => NA
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Eltrombopag dimer-1 impurity
stdClass Object
(
[pname] => Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
[catalogue_number] => PA 32 0221026
[category_ids] => ,103,80,71,78,70,82,162,
[chemical_name] =>
[weight] => 485.5
[form] => C26H23N5O5
[cas] => NA
[pslug] => methyl-z-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-1-nitrosohydrazineyl-2-hydroxy-1-1-biphenyl-3-carboxylate-pa320221026
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Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
stdClass Object
(
[pname] => (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 0221027
[category_ids] => ,70,71,78,80,82,103,162,
[chemical_name] =>
[weight] => 471.47
[form] => C25H21N5O5
[cas] => NA
[pslug] => z-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-hydrazinyl-2-hydroxy-5-nitroso-1-1-biphenyl-3-carboxylic-acid-pa320221027
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(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221027
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
stdClass Object
(
[pname] => (E)-Eltrombopag
[catalogue_number] => PA 32 0221028
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 442.48
[form] => C25H22N4O4
[cas] => NA
[pslug] => e-eltrombopag-pa320221028
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Catalogue No.:PA 32 0221028
Molecular Formula : C25H22N4O4
Molecular Weight : 442.48
stdClass Object
(
[pname] => 3,4-Dimethylbenzenediazonium Chloride
[catalogue_number] => PA 32 0221037
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 168.62
[form] => C8H9ClN2
[cas] => 69457-08-5
[pslug] => 69457-08-5-3-4-dimethylbenzenediazonium-chloride-pa320221037
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3,4-Dimethylbenzenediazonium Chloride
Catalogue No.:PA 32 0221037
Molecular Formula : C8H9ClN2
Molecular Weight : 168.62
stdClass Object
(
[pname] => 2'-(Benzyloxy)-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 0221038
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 349.34
[form] => C20H15NO5
[cas] => 1636137-55-7
[pslug] => 1636137-55-7-2-benzyloxy-3-nitro-1-1-biphenyl-3-carboxylic-acid-pa320221038
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2'-(Benzyloxy)-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221038
Molecular Formula : C20H15NO5
Molecular Weight : 349.34
stdClass Object
(
[pname] => 2'-Methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
[catalogue_number] => PA 32 0221039
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 273.24
[form] => C14H11NO5
[cas] => 376591-94-5
[pslug] => 376591-94-5-2-methoxy-3-nitro-1-1-biphenyl-3-carboxylic-acid-pa320221039
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2'-Methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.:PA 32 0221039
Molecular Formula : C14H11NO5
Molecular Weight : 273.24
