Axitinib-Impurities | Pharmaffiliates

axitinib

Axitinib is an indazole derivative. It is most commonly marketed under the name Inlyta® and is available in oral formulations._x000D_ Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).7. Reference standards of Axitinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => 6-Iodo-1H-indazole
    [catalogue_number] => PA 28 45650
    [category_ids] => ,79,80,71,84,
    [chemical_name] => 
    [weight] => 244.03
    [form] => C7H5IN2
    [cas] => 261953-36-0
    [pslug] => 261953-36-0-6-iodo-1h-indazole-pa2845650
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PA 28 45650

6-Iodo-1H-indazole


  • Catalogue No.:PA 28 45650

  • CAS :

    261953-36-0

  • Molecular Formula : C7H5IN2

  • Molecular Weight : 244.03

stdClass Object
(
    [pname] => 3,6-Diiodo-1H-indazole
    [catalogue_number] => PA 28 45660
    [category_ids] => ,79,80,71,84,
    [chemical_name] => 
    [weight] => 369.93
    [form] => C7H4I2N2
    [cas] => 319472-78-1
    [pslug] => 319472-78-1-3-6-diiodo-1h-indazole-pa2845660
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PA 28 45660

3,6-Diiodo-1H-indazole


  • Catalogue No.:PA 28 45660

  • CAS :

    319472-78-1

  • Molecular Formula : C7H4I2N2

  • Molecular Weight : 369.93

stdClass Object
(
    [pname] => 2-((1-Acetyl-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide
    [catalogue_number] => PA 28 45670
    [category_ids] => 88,80,79,71
    [chemical_name] => 
    [weight] => 341.38
    [form] => C17H15N3O3S
    [cas] => 1959572-98-5
    [pslug] => 1959572-98-5-2-1-acetyl-1h-indazol-6-yl-sulfinyl-n-methylbenzamide-pa2845670
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PA 28 45670

2-((1-Acetyl-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide


  • Catalogue No.:PA 28 45670

  • CAS :

    1959572-98-5

  • Molecular Formula : C17H15N3O3S

  • Molecular Weight : 341.38

stdClass Object
(
    [pname] => 2-((1H-Indazol-6-yl)sulfinyl)-N-methylbenzamide
    [catalogue_number] => PA 28 45680
    [category_ids] => 88,80,79,71,78
    [chemical_name] => 
    [weight] => 299.35
    [form] => C15H13N3O2S
    [cas] => 1959572-97-4
    [pslug] => 1959572-97-4-2-1h-indazol-6-yl-sulfinyl-n-methylbenzamide-pa2845680
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PA 28 45680

2-((1H-Indazol-6-yl)sulfinyl)-N-methylbenzamide


  • Catalogue No.:PA 28 45680

  • CAS :

    1959572-97-4

  • Molecular Formula : C15H13N3O2S

  • Molecular Weight : 299.35

stdClass Object
(
    [pname] => 2,2'-(((2,4-di(Pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-3,6-diyl))bis(sulfanediyl))bis(N-methylbenzamide)
    [catalogue_number] => PA 28 45690
    [category_ids] => 88,80,79,78,71
    [chemical_name] => 
    [weight] => 772.94
    [form] => C44H36N8O2S2
    [cas] => 1428728-83-9
    [pslug] => 1428728-83-9-2-2-2-4-di-pyridin-2-yl-cyclobutane-1-3-diyl-bis-1h-indazole-3-6-diyl-bis-sulfanediyl-bis-n-methylbenzamide-pa2845690
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PA 28 45690

2,2'-(((2,4-di(Pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-3,6-diyl))bis(sulfanediyl))bis(N-methylbenzamide)


  • Catalogue No.:PA 28 45690

  • CAS :

    1428728-83-9

  • Molecular Formula : C44H36N8O2S2

  • Molecular Weight : 772.94

stdClass Object
(
    [pname] => 2-((3-Iodo-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide
    [catalogue_number] => PA 28 45700
    [category_ids] => ,79,80,71,88,78,
    [chemical_name] => 
    [weight] => 425.24
    [form] => C15H12IN3O2S
    [cas] => 1443118-71-5
    [pslug] => 1443118-71-5-2-3-iodo-1h-indazol-6-yl-sulfinyl-n-methylbenzamide-pa2845700
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PA 28 45700

2-((3-Iodo-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide


  • Catalogue No.:PA 28 45700

  • CAS :

    1443118-71-5

  • Molecular Formula : C15H12IN3O2S

  • Molecular Weight : 425.24