brigatinib
Amines
- Brigatinib acts as both an anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR) inhibitor. It is a small molecule targeted cancer therapy being developed by ARIAD Pharmaceuticals, Inc.. Reference standards of Brigatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
(
[pname] => Brigatinib
[catalogue_number] => PA 29 44000
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 584.09
[form] => C29H39ClN7O2P
[cas] => 1197953-54-0
[pslug] => 1197953-54-0-brigatinib-api-pa2944000
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
Catalogue No.:PA 29 44000
Molecular Formula : C29H39ClN7O2P
Molecular Weight : 584.09
stdClass Object
(
[pname] => 2,4-Pyrimidinediamine, 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(1-piperazinyl)-1-piperidinyl]phenyl]
[catalogue_number] => PA 29 0441000
[category_ids] => ,171,78,72,80,79,
[chemical_name] =>
[weight] => 570.07
[form] => C28H37ClN7O2P
[cas] => 1197958-75-0
[pslug] => 1197958-75-0-2-4-pyrimidinediamine-5-chloro-n4-2-dimethylphosphinyl-phenyl-n2-2-methoxy-4-4-1-piperazinyl-1-piperidinyl-phenyl-pa290441000
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
2,4-Pyrimidinediamine, 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(1-piperazinyl)-1-piperidinyl]phenyl]
Catalogue No.:PA 29 0441000
Molecular Formula : C28H37ClN7O2P
Molecular Weight : 570.07
stdClass Object
(
[pname] => N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
[catalogue_number] => PA 29 0441001
[category_ids] => ,78,72,80,79,162,
[chemical_name] =>
[weight] => 613.1
[form] => C29H38ClN8O3P
[cas] => NA
[pslug] => n-5-chloro-4-2-dimethylphosphoryl-phenyl-amino-pyrimidin-2-yl-n-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-nitrous-amide-pa290441001
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
stdClass Object
(
[pname] => N-(5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-N-(2-(dimethylphosphoryl)phenyl)nitrous amide
[catalogue_number] => PA 29 0441002
[category_ids] => ,78,72,80,79,162,
[chemical_name] =>
[weight] => 613.1
[form] => C29H38ClN8O3P
[cas] => NA
[pslug] => n-5-chloro-2-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-amino-pyrimidin-4-yl-n-2-dimethylphosphoryl-phenyl-nitrous-amide-pa290441002
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
N-(5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-N-(2-(dimethylphosphoryl)phenyl)nitrous amide
stdClass Object
(
[pname] => N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)(nitroso)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
[catalogue_number] => PA 29 0441003
[category_ids] => ,78,72,80,79,162,
[chemical_name] =>
[weight] => 642.1
[form] => C29H37ClN9O4P
[cas] => NA
[pslug] => n-5-chloro-4-2-dimethylphosphoryl-phenyl-nitroso-amino-pyrimidin-2-yl-n-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-nitrous-amide-pa290441003
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)(nitroso)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
stdClass Object
(
[pname] => 5-Methyl Brigatinib
[catalogue_number] => PA 29 0441004
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 598.13
[form] => C30H41ClN7O2P
[cas] => 1197961-02-6
[pslug] => 1197961-02-6-5-methyl-brigatinib-pa290441004
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
Catalogue No.:PA 29 0441004
Molecular Formula : C30H41ClN7O2P
Molecular Weight : 598.13
stdClass Object
(
[pname] => 5-Chloro-N2,N4-bis(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine
[catalogue_number] => PA 29 0441005
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 719.38
[form] => C38H55ClN10O2
[cas] => NA
[pslug] => 5-chloro-n2-n4-bis-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-pyrimidine-2-4-diamine-pa290441005
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
5-Chloro-N2,N4-bis(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine
Catalogue No.:PA 29 0441005
Molecular Formula : C38H55ClN10O2
Molecular Weight : 719.38
stdClass Object
(
[pname] => (2-((5-Chloro-2-((4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
[catalogue_number] => PA 29 0441006
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 501.95
[form] => C24H29ClN5O3P
[cas] => 1197959-30-0
[pslug] => 1197959-30-0-2-5-chloro-2-4-4-hydroxypiperidin-1-yl-2-methoxyphenyl-amino-pyrimidin-4-yl-amino-phenyl-dimethylphosphine-oxide-pa290441006
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
(2-((5-Chloro-2-((4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
Catalogue No.:PA 29 0441006
Molecular Formula : C24H29ClN5O3P
Molecular Weight : 501.95
stdClass Object
(
[pname] => 2,5-Dichloro-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidin-4-amine
[catalogue_number] => PA 29 0441007
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 451.4
[form] => C21H28Cl2N6O
[cas] => 1259274-28-6
[pslug] => 1259274-28-6-2-5-dichloro-n-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-pyrimidin-4-amine-pa290441007
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
2,5-Dichloro-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidin-4-amine
stdClass Object
(
[pname] => O-Ethyl Brigatinib
[catalogue_number] => PA 29 0441008
[category_ids] => ,78,72,80,79,
[chemical_name] =>
[weight] => 598.13
[form] => C30H41ClN7O2P
[cas] => 1197960-18-1
[pslug] => 1197960-18-1-o-ethyl-brigatinib-pa290441008
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
Catalogue No.:PA 29 0441008
Molecular Formula : C30H41ClN7O2P
Molecular Weight : 598.13
stdClass Object
(
[pname] => N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
[catalogue_number] => PA 29 0441009
[category_ids] => ,78,72,80,79,162,
[chemical_name] =>
[weight] => 613.1
[form] => C29H38ClN8O3P
[cas] => NA
[pslug] => n-5-chloro-4-2-dimethylphosphoryl-phenyl-amino-pyrimidin-2-yl-n-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-nitrous-amide-pa290441009
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
N-(5-Chloro-4-((2-(dimethylphosphoryl)phenyl)amino)pyrimidin-2-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)nitrous amide
stdClass Object
(
[pname] => N-(5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-N-(2-(dimethylphosphoryl)phenyl)nitrous amide
[catalogue_number] => PA 29 0441011
[category_ids] => ,78,72,80,79,162,
[chemical_name] =>
[weight] => 613.1
[form] => C29H38ClN8O3P
[cas] => NA
[pslug] => n-5-chloro-2-2-methoxy-4-4-4-methylpiperazin-1-yl-piperidin-1-yl-phenyl-amino-pyrimidin-4-yl-n-2-dimethylphosphoryl-phenyl-nitrous-amide-pa290441011
[latest_product] => 0
[linkproducts] => 0
[offers_id] =>
[offers_name] =>
[offers_status] =>
[offers_start_date] =>
[offers_end_date] =>
[pageview] =>
[offers_slug] =>
[offers_product_id] =>
[offers_product_code] =>
[offers_master_id] =>
[offer_percentage] =>
[offers_product_main_cat] =>
)
N-(5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-N-(2-(dimethylphosphoryl)phenyl)nitrous amide
