decitabine

Decitabine is used to treat myelodysplastic syndromes. It is a cytosine analogue and an intravenously administered antineoplastic agent.. Reference standards of Decitabine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [catalogue_number] => PA 04 75520
    [category_ids] => ,78,70,82,79,
    [chemical_name] => 
    [weight] => 492.44
    [form] => C16H28N8O10
    [cas] => NA
    [pslug] => 4-amino-6-hydroxy-1-2r-4s-5r-4-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-5-6-dihydro-1-3-5-triazin-2-1h-one-4-amino-6-hydroxy-1-2r-4s-5r-4-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-5-6-dihydro-1-3-5-triazin-2-1h-one-pa0475520
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PA 04 75520

4-Amino-6-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5,6-dihydro-1,3,5-triazin-2(1H)-one + 4-Amino-6-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5,6-dihydro-1,3,5-triazin-2(1H)-one

  • Catalogue No.:PA 04 75520

  • CAS :

    NA

  • Molecular Formula : C16H28N8O10

  • Molecular Weight : 492.44

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Details 
stdClass Object
(
    [pname] => 1,3,5-Triazine-2,4-diamine
    [catalogue_number] => PA 04 75530
    [category_ids] => ,78,70,82,79,
    [chemical_name] => 
    [weight] => 111.11
    [form] => C3H5N5
    [cas] => 504-08-5
    [pslug] => 504-08-5-1-3-5-triazine-2-4-diamine-pa0475530
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PA 04 75530

1,3,5-Triazine-2,4-diamine

  • Catalogue No.:PA 04 75530

  • CAS :

    504-08-5

  • Molecular Formula : C3H5N5

  • Molecular Weight : 111.11

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Details 
stdClass Object
(
    [pname] => Decitabine Ring-opening Impurity
    [catalogue_number] => PA 04 75590
    [category_ids] => ,78,70,82,79,
    [chemical_name] => 
    [weight] => 246.22
    [form] => C8H14N4O5
    [cas] => 69304-64-9
    [pslug] => 69304-64-9-decitabine-ring-opening-impurity-pa0475590
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PA 04 75590

Decitabine Ring-opening Impurity

  • Catalogue No.:PA 04 75590

  • CAS :

    69304-64-9

  • Molecular Formula : C8H14N4O5

  • Molecular Weight : 246.22

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Details 
stdClass Object
(
    [pname] => β-Decitabine-3',5'-bis(4-chlorobenzoate)
    [catalogue_number] => PA 04 75620
    [category_ids] => ,79,80,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 505.31
    [form] => C22H18Cl2N4O6
    [cas] => 1034301-08-0
    [pslug] => 1034301-08-0-beta-decitabine-3-5-bis-4-chlorobenzoate-pa0475620
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PA 04 75620

β-Decitabine-3',5'-bis(4-chlorobenzoate)

  • Catalogue No.:PA 04 75620

  • CAS :

    1034301-08-0

  • Molecular Formula : C22H18Cl2N4O6

  • Molecular Weight : 505.31

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Details 
stdClass Object
(
    [pname] => (2R,3S,5S)-5-Acetoxy-2-(((4-Chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate
    [catalogue_number] => PA 04 75630
    [category_ids] => ,79,80,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 453.27
    [form] => C21H18Cl2O7
    [cas] => 1019659-87-0
    [pslug] => 1019659-87-0-2r-3s-5s-5-acetoxy-2-4-chlorobenzoyl-oxy-methyl-tetrahydrofuran-3-yl-4-chlorobenzoate-pa0475630
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PA 04 75630

(2R,3S,5S)-5-Acetoxy-2-(((4-Chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate

  • Catalogue No.:PA 04 75630

  • CAS :

    1019659-87-0

  • Molecular Formula : C21H18Cl2O7

  • Molecular Weight : 453.27

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Details 
stdClass Object
(
    [pname] => α-Decitabine-3',5'-bis(4-chlorobenzoate)
    [catalogue_number] => PA 04 75640
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 505.31
    [form] => C22H18Cl2N4O6
    [cas] => 1140891-02-6
    [pslug] => 1140891-02-6-alpha-decitabine-3-5-bis-4-chlorobenzoate-pa0475640
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PA 04 75640

α-Decitabine-3',5'-bis(4-chlorobenzoate)

  • Catalogue No.:PA 04 75640

  • CAS :

    1140891-02-6

  • Molecular Formula : C22H18Cl2N4O6

  • Molecular Weight : 505.31

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Details 
stdClass Object
(
    [pname] => 4-Amino-1-(3,5-di-O-acetyl-2-deoxy-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
    [catalogue_number] => PA 04 75660
    [category_ids] => ,78,82,70,79,
    [chemical_name] => 
    [weight] => 312.28
    [form] => C12H16N4O6
    [cas] => 22432-93-5
    [pslug] => 22432-93-5-4-amino-1-3-5-di-o-acetyl-2-deoxy-d-erythro-pentofuranosyl-1-3-5-triazin-2-1h-one-pa0475660
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PA 04 75660

4-Amino-1-(3,5-di-O-acetyl-2-deoxy-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one

  • Catalogue No.:PA 04 75660

  • CAS :

    22432-93-5

  • Molecular Formula : C12H16N4O6

  • Molecular Weight : 312.28

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Details 
stdClass Object
(
    [pname] => (2R,5R)-2-(Hydroxymethyl)-5-methoxyoxolan-3-ol
    [catalogue_number] => PA 04 75670
    [category_ids] => ,78,82,70,79,
    [chemical_name] => 
    [weight] => 148.16
    [form] => C6H12O4
    [cas] => 51255-17-5
    [pslug] => 51255-17-5-2r-5r-2-hydroxymethyl-5-methoxyoxolan-3-ol-pa0475670
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PA 04 75670

(2R,5R)-2-(Hydroxymethyl)-5-methoxyoxolan-3-ol

  • Catalogue No.:PA 04 75670

  • CAS :

    51255-17-5

  • Molecular Formula : C6H12O4

  • Molecular Weight : 148.16

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Details 
stdClass Object
(
    [pname] => 2-Deoxy-D-β-ribopyranosyl-5-azacytosine-15N4
    [catalogue_number] => PA STI 026580
    [category_ids] => ,70,71,78,79,80,82,98,
    [chemical_name] => 
    [weight] => 232.18
    [form] => C8H1215N4O4
    [cas] => NA
    [pslug] => 2-deoxy-d-beta-ribopyranosyl-5-azacytosine-15n4-pasti026580
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PA STI 026580

2-Deoxy-D-β-ribopyranosyl-5-azacytosine-15N4

  • Catalogue No.:PA STI 026580

  • CAS :

    NA

  • Molecular Formula : C8H1215N4O4

  • Molecular Weight : 232.18

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Details 
stdClass Object
(
    [pname] => 2,4-Diamino-6-hydroxypyrimidine
    [catalogue_number] => PA 04 75700
    [category_ids] => ,79,71,85,83,
    [chemical_name] => 
    [weight] => 126.12
    [form] => C4H6N4O
    [cas] => 56-06-4
    [pslug] => 56-06-4-2-4-diamino-6-hydroxypyrimidine-pa0475700
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PA 04 75700

2,4-Diamino-6-hydroxypyrimidine

  • Catalogue No.:PA 04 75700

  • CAS :

    56-06-4

  • Molecular Formula : C4H6N4O

  • Molecular Weight : 126.12

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Details 
stdClass Object
(
    [pname] => N-((Z)-N'-(((2R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)carbamoyl)carbamimidoyl)formamide
    [catalogue_number] => PA 04 0751023
    [category_ids] => ,78,70,82,79,
    [chemical_name] => 
    [weight] => 246.22
    [form] => C8H14N4O5
    [cas] => NA
    [pslug] => n-z-n-2r-4r-5r-4-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-carbamoyl-carbamimidoyl-formamide-pa040751023
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PA 04 0751023

N-((Z)-N'-(((2R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)carbamoyl)carbamimidoyl)formamide

  • Catalogue No.:PA 04 0751023

  • CAS :

    NA

  • Molecular Formula : C8H14N4O5

  • Molecular Weight : 246.22

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CPHI INDIA- 28, 30 November