ezetimibe

Amines - An anti-hyperlipidemic medication, it is used for cholesterol lowering that decreases the absorption of cholesterol in the small intestine. Ezetimibe is hence used for treating high cholesterol. Reference standards of Ezetimibe API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Methyl 5-(4-fluorophenyl)-5-hydroxypentanoate
    [catalogue_number] => PA 05 41020
    [category_ids] => ,92,79,80,89,
    [chemical_name] => 
    [weight] => 226.25
    [form] => C12H15FO3
    [cas] => 1368310-60-4
    [pslug] => 1368310-60-4-methyl 5-4-fluorophenyl-5-hydroxypentanoate-pa0541020
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PA 05 41020
PA 05 41020

Methyl 5-(4-fluorophenyl)-5-hydroxypentanoate


  • Catalogue No.:PA 05 41020

  • CAS :

    1368310-60-4

  • Molecular Formula : C12H15FO3

  • Molecular Weight : 226.25

stdClass Object
(
    [pname] => Ezetimibe m-Fluoroaniline Analog
    [catalogue_number] => PA 05 41540
    [category_ids] => ,89,82,81,80,79,78,70,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1700622-06-5
    [pslug] => 1700622-06-5-ezetimibe-m-fluoroaniline-analog-pa0541540
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PA 05 41540
PA 05 41540

Ezetimibe m-Fluoroaniline Analog


  • Catalogue No.:PA 05 41540

  • CAS :

    1700622-06-5

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity A
    [catalogue_number] => PA 05 41550
    [category_ids] => ,89,82,80,79,78,74,71,70,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593543-07-7
    [pslug] => 1593543-07-7-ezetimibe-impurity-a-pa0541550
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PA 05 41550
PA 05 41550

Ezetimibe - Impurity A


  • Catalogue No.:PA 05 41550

  • CAS :

    1593543-07-7

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity B
    [catalogue_number] => PA 05 41560
    [category_ids] => ,70,71,74,78,79,80,82,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 163380-16-3
    [pslug] => 163380-16-3-ezetimibe-impurity-b-pa0541560
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PA 05 41560
PA 05 41560

Ezetimibe - Impurity B


  • Catalogue No.:PA 05 41560

  • CAS :

    163380-16-3

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe (SSR)-Isomer
    [catalogue_number] => PA 05 41570
    [category_ids] => ,75,81,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593543-00-0
    [pslug] => 1593543-00-0-ezetimibe-ssr-isomer-pa0541570
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PA 05 41570
PA 05 41570

Ezetimibe (SSR)-Isomer


  • Catalogue No.:PA 05 41570

  • CAS :

    1593543-00-0

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe - Impurity G
    [catalogue_number] => PA 05 41580
    [category_ids] => ,79,81,80,71,70,78,82,75,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1376614-99-1
    [pslug] => 1376614-99-1-ezetimibe-impurity-g-pa0541580
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PA 05 41580
PA 05 41580

Ezetimibe - Impurity G


  • Catalogue No.:PA 05 41580

  • CAS :

    1376614-99-1

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe Diol Impurity
    [catalogue_number] => PA 05 41590
    [category_ids] => ,80,71,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 413.46
    [form] => C24H25F2NO3
    [cas] => 1374250-08-4
    [pslug] => 1374250-08-4-ezetimibe-diol-impurity-pa0541590
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PA 05 41590
PA 05 41590

Ezetimibe Diol Impurity


  • Catalogue No.:PA 05 41590

  • CAS :

    1374250-08-4

  • Molecular Formula : C24H25F2NO3

  • Molecular Weight : 413.46

stdClass Object
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    [pname] => (4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41670
    [category_ids] => ,80,78,70,82,89,79,71,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 272778-12-8
    [pslug] => 272778-12-8-4s3-2r-5s-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-1-oxo-5-trimethylsilyl-oxy-pentyl-4-phenyl-2-oxazolidinone-pa0541670
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PA 05 41670
PA 05 41670

(4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41670

  • CAS :

    272778-12-8

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one
    [catalogue_number] => PA 05 41690
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 389.42
    [form] => C24H20FNO3
    [cas] => 163222-31-9
    [pslug] => 163222-31-9-3r-4s-1-4-fluorophenyl-4-4-hydroxyphenyl-3-3-oxo-3-phenylpropyl-azetidin-2-one-pa0541690
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PA 05 41690
PA 05 41690

(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one


  • Catalogue No.:PA 05 41690

  • CAS :

    163222-31-9

  • Molecular Formula : C24H20FNO3

  • Molecular Weight : 389.42

stdClass Object
(
    [pname] => Mixture of (Ezetimibe Keto Isomer, Ezetimibe Keto And Ezetimibe) 
    [catalogue_number] => PA 05 41700
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 1224.24
    [form] => C72H59F6N3O9
    [cas] => NA
    [pslug] => mixture-of-ezetimibe-keto-isomer-ezetimibe-keto-and-ezetimibe-pa0541700
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PA 05 41700
PA 05 41700

Mixture of (Ezetimibe Keto Isomer, Ezetimibe Keto And Ezetimibe)


  • Catalogue No.:PA 05 41700

  • CAS :

    NA

  • Molecular Formula : C72H59F6N3O9

  • Molecular Weight : 1224.24

stdClass Object
(
    [pname] => Mixture of (Ezetimibe and Ezetimibe (RRS)-Isomer)
    [catalogue_number] => PA 05 41710
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 818.85
    [form] => C48H42F4N2O6
    [cas] => NA
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PA 05 41710
PA 05 41710

Mixture of (Ezetimibe and Ezetimibe (RRS)-Isomer)


  • Catalogue No.:PA 05 41710

  • CAS :

    NA

  • Molecular Formula : C48H42F4N2O6

  • Molecular Weight : 818.85

stdClass Object
(
    [pname] => Mixture of (Des-F Ezetimibe-15 And Ezetimibe-15)
    [catalogue_number] => PA 05 41720
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 692.73
    [form] => C40H37FN2O8
    [cas] => NA
    [pslug] => mixture-of-des-f-ezetimibe-15-and-ezetimibe-15-pa0541720
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PA 05 41720
PA 05 41720

Mixture of (Des-F Ezetimibe-15 And Ezetimibe-15)


  • Catalogue No.:PA 05 41720

  • CAS :

    NA

  • Molecular Formula : C40H37FN2O8

  • Molecular Weight : 692.73

stdClass Object
(
    [pname] => Mixture of (Des-fluoro-A Ezetimibe And Des-fluoro-B Ezetimibe)
    [catalogue_number] => PA 05 41730
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 1192.29
    [form] => C72H65F4N3O9
    [cas] => NA
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PA 05 41730
PA 05 41730

Mixture of (Des-fluoro-A Ezetimibe And Des-fluoro-B Ezetimibe)


  • Catalogue No.:PA 05 41730

  • CAS :

    NA

  • Molecular Formula : C72H65F4N3O9

  • Molecular Weight : 1192.29

stdClass Object
(
    [pname] => Mixtuure of (Ezetimibe Acid And Ezetimibe RRS Acid)
    [catalogue_number] => PA 05 41740
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 866.75
    [form] => C48H44F4Li2N2O8
    [cas] => NA
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PA 05 41740
PA 05 41740

Mixtuure of (Ezetimibe Acid And Ezetimibe RRS Acid)


  • Catalogue No.:PA 05 41740

  • CAS :

    NA

  • Molecular Formula : C48H44F4Li2N2O8

  • Molecular Weight : 866.75

stdClass Object
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    [pname] => 3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one
    [catalogue_number] => PA 05 41770
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 357.38
    [form] => C20H20FNO4
    [cas] => 189028-95-3
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PA 05 41770
PA 05 41770

3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one


  • Catalogue No.:PA 05 41770

  • CAS :

    189028-95-3

  • Molecular Formula : C20H20FNO4

  • Molecular Weight : 357.38

stdClass Object
(
    [pname] => 1-Phenyl 3(R)-[3(S)-(4-Fluorophenyl)-3-hydroxypropyl]-4(S)-(4-hydroxyphenyl)azetidin-2-one
    [catalogue_number] => PA 05 41780
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 391.43
    [form] => C24H22FNO3
    [cas] => NA
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PA 05 41780
PA 05 41780

1-Phenyl 3(R)-[3(S)-(4-Fluorophenyl)-3-hydroxypropyl]-4(S)-(4-hydroxyphenyl)azetidin-2-one


  • Catalogue No.:PA 05 41780

  • CAS :

    NA

  • Molecular Formula : C24H22FNO3

  • Molecular Weight : 391.43

stdClass Object
(
    [pname] => 4-Fluoroaniline
    [catalogue_number] => PA 05 41790
    [category_ids] => ,79,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 111.12
    [form] => C6H6FN
    [cas] => 371-40-4
    [pslug] => 371-40-4-4-fluoroaniline-pa0541790
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PA 05 41790
PA 05 41790

4-Fluoroaniline


  • Catalogue No.:PA 05 41790

  • CAS :

    371-40-4

  • Molecular Formula : C6H6FN

  • Molecular Weight : 111.12

stdClass Object
(
    [pname] => (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41920
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 572.6
    [form] => C33H30F2N2O5
    [cas] => 1185883-40-2
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PA 05 41920
PA 05 41920

(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41920

  • CAS :

    1185883-40-2

  • Molecular Formula : C33H30F2N2O5

  • Molecular Weight : 572.6

stdClass Object
(
    [pname] => (S)-3-((S)-5-(4-Fluorophenyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41930
    [category_ids] => ,89,80,79,92,
    [chemical_name] => 
    [weight] => 429.56
    [form] => C23H28FNO4Si
    [cas] => 1354716-94-1
    [pslug] => 1354716-94-1-s-3-s-5-4-fluorophenyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541930
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PA 05 41930
PA 05 41930

(S)-3-((S)-5-(4-Fluorophenyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41930

  • CAS :

    1354716-94-1

  • Molecular Formula : C23H28FNO4Si

  • Molecular Weight : 429.56

stdClass Object
(
    [pname] => (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41940
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 644.78
    [form] => C36H38F2N2O5Si
    [cas] => NA
    [pslug] => s-3-2r-5s-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-hydroxyphenyl-methyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541940
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PA 05 41940
PA 05 41940

(S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41940

  • CAS :

    NA

  • Molecular Formula : C36H38F2N2O5Si

  • Molecular Weight : 644.78

stdClass Object
(
    [pname] => (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41950
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => NA
    [pslug] => 4s-3-2r-5s-5-4-fluorophenyl-2-r-3-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-1-oxo-5-trimethylsilyl-oxy-pentyl-4-phenyl-2-oxazolidinone-pa0541950
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PA 05 41950
PA 05 41950

(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41950

  • CAS :

    NA

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => (S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41960
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 1809031-15-9
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PA 05 41960
PA 05 41960

(S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41960

  • CAS :

    1809031-15-9

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => Ezetimibe Tetrahydropyran-d4 Impurity
    [catalogue_number] => PA STI 040540
    [category_ids] => ,79,80,69,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 413.45
    [form] => C24H17D4F2NO3
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PA STI 040540
PA STI 040540

Ezetimibe Tetrahydropyran-d4 Impurity


  • Catalogue No.:PA STI 040540

  • CAS :

    NA

  • Molecular Formula : C24H17D4F2NO3

  • Molecular Weight : 413.45

stdClass Object
(
    [pname] => (3R,4S)-1-(3-Fluorophenyl)-3-(3-(4-fluorophenyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
    [catalogue_number] => PA 05 41515
    [category_ids] => ,89,80,79,92,
    [chemical_name] => 
    [weight] => 393.43
    [form] => C24H21F2NO2
    [cas] => NA
    [pslug] => 3r-4s-1-3-fluorophenyl-3-3-4-fluorophenyl-propyl-4-4-hydroxyphenyl-azetidin-2-one-pa0541515
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PA 05 41515
PA 05 41515

(3R,4S)-1-(3-Fluorophenyl)-3-(3-(4-fluorophenyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one


  • Catalogue No.:PA 05 41515

  • CAS :

    NA

  • Molecular Formula : C24H21F2NO2

  • Molecular Weight : 393.43

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