gefitinib
Amines
- Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Gefitinib
[catalogue_number] => PA 07 24000
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 446.90
[form] => C22H24ClFN4O3
[cas] => 184475-35-2
[pslug] => 184475-35-2-gefitinib-api-pa0724000
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Catalogue No.:PA 07 24000
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.90
stdClass Object
(
[pname] => Gefitinib - Impurity B
[catalogue_number] => PA 07 24020
[category_ids] => ,82,80,79,78,71,70,
[chemical_name] =>
[weight] => 446.90
[form] => C22H24ClFN4O3
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Catalogue No.:PA 07 24020
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.90
stdClass Object
(
[pname] => Gefitinib 4-Desfluoro Hydrochloride Impurity
[catalogue_number] => PA 07 24520
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 465.37
[form] => C22H26Cl2N4O3
[cas] => NA
[pslug] => gefitinib-4-desfluoro-hydrochloride-impurity-pa0724520
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Gefitinib 4-Desfluoro Hydrochloride Impurity
Catalogue No.:PA 07 24520
Molecular Formula : C22H26Cl2N4O3
Molecular Weight : 465.37
stdClass Object
(
[pname] => Gefitinib N-Oxide
[catalogue_number] => PA 07 24530
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 462.9
[form] => C22H24ClFN4O4
[cas] => 847949-51-3
[pslug] => 847949-51-3-gefitinib-n-oxide-pa0724530
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stdClass Object
(
[pname] => 3,4-Dichloroaniline
[catalogue_number] => PA 07 24570
[category_ids] => ,79,80,84,
[chemical_name] =>
[weight] => 162.02
[form] => C6H5Cl2N
[cas] => 95-76-1
[pslug] => 95-76-1-3-4-dichloroaniline-pa0724570
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Catalogue No.:PA 07 24570
Molecular Formula : C6H5Cl2N
Molecular Weight : 162.02
stdClass Object
(
[pname] => 6-Hydroxy-7-methoxy-4(1H)-quinazolinone
[catalogue_number] => PA 07 24690
[category_ids] => ,80,79,78,82,70,
[chemical_name] =>
[weight] => 192.17
[form] => C9H8N2O3
[cas] => 179688-52-9
[pslug] => 179688-52-9-6-hydroxy-7-methoxy-4-1h-quinazolinone-pa0724690
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6-Hydroxy-7-methoxy-4(1H)-quinazolinone
Catalogue No.:PA 07 24690
Molecular Formula : C9H8N2O3
Molecular Weight : 192.17
stdClass Object
(
[pname] => 4-Isopropoxy-7-methoxyquinazolin-6-yl acetate
[catalogue_number] => PA 07 24700
[category_ids] => ,80,79,78,82,70,
[chemical_name] =>
[weight] => 276.29
[form] => C14H16N2O4
[cas] => NA
[pslug] => 4-isopropoxy-7-methoxyquinazolin-6-yl-acetate-pa0724700
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4-Isopropoxy-7-methoxyquinazolin-6-yl acetate
Catalogue No.:PA 07 24700
Molecular Formula : C14H16N2O4
Molecular Weight : 276.29
stdClass Object
(
[pname] => Gefitinib-d3
[catalogue_number] => PA STI 044040
[category_ids] => ,79,80,71,78,70,82,98,
[chemical_name] =>
[weight] => 449.92
[form] => C22H21D3ClFN4O3
[cas] => 1173976-40-3
[pslug] => 1173976-40-3-gefitinib-d3-pasti044040
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Catalogue No.:PA STI 044040
Molecular Formula : C22H21D3ClFN4O3
Molecular Weight : 449.92
stdClass Object
(
[pname] => Gefitinib-D6
[catalogue_number] => PA STI 089397
[category_ids] => ,98,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 452.94
[form] => C22H18D6ClFN4O3
[cas] => 1228664-49-0
[pslug] => 1228664-49-0-gefitinib-d6-pasti089397
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Catalogue No.:PA STI 089397
Molecular Formula : C22H18D6ClFN4O3
Molecular Weight : 452.94
stdClass Object
(
[pname] => 1,3-Dimorpholinopropane
[catalogue_number] => PA 07 0241006
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 214.31
[form] => C11H22N2O2
[cas] => 48152-09-6
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Catalogue No.:PA 07 0241006
Molecular Formula : C11H22N2O2
Molecular Weight : 214.31
stdClass Object
(
[pname] => 6,7-Dimethoxyquinazolin-4(3H)-one
[catalogue_number] => PA 07 0241007
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 206.2
[form] => C10H10N2O3
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6,7-Dimethoxyquinazolin-4(3H)-one
stdClass Object
(
[pname] => Methyl 2-amino-4,5-dimethoxybenzoate
[catalogue_number] => PA 07 0241008
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[chemical_name] =>
[weight] => 211.22
[form] => C10H13NO4
[cas] => 26759-46-6
[pslug] => 26759-46-6-methyl-2-amino-4-5-dimethoxybenzoate-pa070241008
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Methyl 2-amino-4,5-dimethoxybenzoate
Catalogue No.:PA 07 0241008
Molecular Formula : C10H13NO4
Molecular Weight : 211.22
stdClass Object
(
[pname] => 2-Chloro-1-fluoro-4-nitrobenzene
[catalogue_number] => PA 07 0241009
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 175.54
[form] => C6H3ClFNO2
[cas] => 350-30-1
[pslug] => 350-30-1-2-chloro-1-fluoro-4-nitrobenzene-pa070241009
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2-Chloro-1-fluoro-4-nitrobenzene
Catalogue No.:PA 07 0241009
Molecular Formula : C6H3ClFNO2
Molecular Weight : 175.54
stdClass Object
(
[pname] => N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 0241010
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 446.91
[form] => C22H24ClFN4O3
[cas] => 909863-33-8
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N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 0241010
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.91
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 0241011
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[weight] => 446.91
[form] => C22H24ClFN4O3
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N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 0241011
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.91
