ledipasvir
Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. Reference standards of Ledipasvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Ledipasvir
[catalogue_number] => PA 12 77000
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 889.00
[form] => C49H54F2N8O6
[cas] => 1256388-51-8
[pslug] => 1256388-51-8-ledipasvir-api-pa1277000
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Catalogue No.:PA 12 77000
Molecular Formula : C49H54F2N8O6
Molecular Weight : 889.00
stdClass Object
(
[pname] => tert-Butyl (1R,3R,4S)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
[catalogue_number] => PA 12 77510
[category_ids] => ,90,79,75,
[chemical_name] =>
[weight] => 439.36
[form] => C24H34BN3O4
[cas] => NA
[pslug] => tert-butyl-1r-3r-4s-3-6-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-benzo-d-imidazol-2-yl-2-azabicyclo-2-2-1-heptane-2-carboxylate-pa1277510
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tert-Butyl (1R,3R,4S)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
Catalogue No.:PA 12 77510
Molecular Formula : C24H34BN3O4
Molecular Weight : 439.36
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[pname] => tert-Butyl (1S,3S,4R)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
[catalogue_number] => PA 12 77520
[category_ids] => ,90,79,75,
[chemical_name] =>
[weight] => 439.36
[form] => C24H34BN3O4
[cas] => NA
[pslug] => tert-butyl-1s-3s-4r-3-6-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-benzo-d-imidazol-2-yl-2-azabicyclo-2-2-1-heptane-2-carboxylate-pa1277520
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tert-Butyl (1S,3S,4R)-3-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
Catalogue No.:PA 12 77520
Molecular Formula : C24H34BN3O4
Molecular Weight : 439.36
stdClass Object
(
[pname] => 2-Amino-4'-bromoacetophenone Hydrochloride
[catalogue_number] => PA 12 77530
[category_ids] => ,79,80,
[chemical_name] =>
[weight] => 250.52
[form] => C8H9BrClNO
[cas] => 5467-72-1
[pslug] => 5467-72-1-2-amino-4-bromoacetophenone-hydrochloride-pa1277530
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2-Amino-4'-bromoacetophenone Hydrochloride
Catalogue No.:PA 12 77530
Molecular Formula : C8H9BrClNO
Molecular Weight : 250.52
stdClass Object
(
[pname] => Ledipasvir-d6
[catalogue_number] => PA STI 056231
[category_ids] => ,79,80,77,69,71,98,78,70,82,
[chemical_name] =>
[weight] => 895.04
[form] => C49H48D6F2N8O6
[cas] => NA
[pslug] => ledipasvir-d6-pasti056231
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Catalogue No.:PA STI 056231
Molecular Formula : C49H48D6F2N8O6
Molecular Weight : 895.04
stdClass Object
(
[pname] => Ledipasvir Acetyl Spiro Impurity
[catalogue_number] => PA 12 0771005
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 773.89
[form] => C44H45F2N7O4
[cas] => 2040487-36-1
[pslug] => 2040487-36-1-ledipasvir-acetyl-spiro-impurity-pa120771005
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Ledipasvir Acetyl Spiro Impurity
Catalogue No.:PA 12 0771005
Molecular Formula : C44H45F2N7O4
Molecular Weight : 773.89
stdClass Object
(
[pname] => 6-(7-(2-((S)-5-Azaspiro[2.4]heptan-6-yl)-1H-imidazol-5-yl)-9,9-difluoro-9H-fluoren-2-yl)-2-((1R,3S,4S)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazole tetrahydrochloride
[catalogue_number] => PA 12 0771007
[category_ids] => ,79,80,77,69,71,78,70,82,
[chemical_name] =>
[weight] => 720.51
[form] => C35H36Cl4F2N6
[cas] => 1499193-67-7
[pslug] => 1499193-67-7-6-7-2-s-5-azaspiro-2-4-heptan-6-yl-1h-imidazol-5-yl-9-9-difluoro-9h-fluoren-2-yl-2-1r-3s-4s-2-azabicyclo-2-2-1-heptan-3-yl-1h-benzo-d-imidazole-tetrahydrochloride-pa120771007
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6-(7-(2-((S)-5-Azaspiro[2.4]heptan-6-yl)-1H-imidazol-5-yl)-9,9-difluoro-9H-fluoren-2-yl)-2-((1R,3S,4S)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazole tetrahydrochloride
Catalogue No.:PA 12 0771007
Molecular Formula : C35H36Cl4F2N6
Molecular Weight : 720.51
stdClass Object
(
[pname] => Acetyl-L-threonine
[catalogue_number] => PA 12 0771006
[category_ids] => ,70,78,79,80,82,
[chemical_name] =>
[weight] => 161.16
[form] => C6H11NO4
[cas] => 17093-74-2
[pslug] => 17093-74-2-acetyl-l-threonine-pa120771006
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Catalogue No.:PA 12 0771006
Molecular Formula : C6H11NO4
Molecular Weight : 161.16