nilotinib

Amines - Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Nilotinib - Impurity C
    [catalogue_number] => PA 14 64520
    [category_ids] => ,80,79,71,
    [chemical_name] => 
    [weight] => 151.16
    [form] => C8H9NO2
    [cas] => 2458-12-0
    [pslug] => 2458-12-0-nilotinib-impurity-c-pa1464520
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PA 14 64520
PA 14 64520

Nilotinib - Impurity C

  • Catalogue No.:PA 14 64520

  • CAS :

    2458-12-0

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.16

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Details 
stdClass Object
(
    [pname] => 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
    [catalogue_number] => PA 14 64530
    [category_ids] => ,79,80,70,84,
    [chemical_name] => 
    [weight] => 241.21
    [form] => C11H10F3N3
    [cas] => 641571-16-6
    [pslug] => 641571-16-6-3-5-methyl-1h-imidazol-1-yl-5-trifluoromethyl-benzenamine-pa1464530
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PA 14 64530
PA 14 64530

3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine

  • Catalogue No.:PA 14 64530

  • CAS :

    641571-16-6

  • Molecular Formula : C11H10F3N3

  • Molecular Weight : 241.21

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Details 
stdClass Object
(
    [pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
    [catalogue_number] => PA 14 64540
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 271.2
    [form] => C11H8F3N3O2
    [cas] => 916975-92-3
    [pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540
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PA 14 64540
PA 14 64540

4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole

  • Catalogue No.:PA 14 64540

  • CAS :

    916975-92-3

  • Molecular Formula : C11H8F3N3O2

  • Molecular Weight : 271.2

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Details 
stdClass Object
(
    [pname] => Nilotinib - Impurity H (Hydrochloride Salt)
    [catalogue_number] => PA 14 64550
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 565.98
    [form] => C28H23ClF3N7O
    [cas] => NA
    [pslug] => -nilotinib-impurity-h-hydrochloride-salt-pa1464550
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PA 14 64550
PA 14 64550

Nilotinib - Impurity H (Hydrochloride Salt)

  • Catalogue No.:PA 14 64550

  • CAS :

    NA

  • Molecular Formula : C28H23ClF3N7O

  • Molecular Weight : 565.98

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stdClass Object
(
    [pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 64560
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 563.96
    [form] => C28H21ClF3N7O
    [cas] => NA
    [pslug] => 3-4-chloro-6-pyridin-3-yl-pyrimidin-2-yl-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa1464560
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PA 14 64560
PA 14 64560

3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 14 64560

  • CAS :

    NA

  • Molecular Formula : C28H21ClF3N7O

  • Molecular Weight : 563.96

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Details 
stdClass Object
(
    [pname] => Nilotinib - Impurity H (Freebase)
    [catalogue_number] => PA 14 64570
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 529.52
    [form] => C28H22F3N7O
    [cas] => 641571-15-5
    [pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570
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PA 14 64570
PA 14 64570

Nilotinib - Impurity H (Freebase)

  • Catalogue No.:PA 14 64570

  • CAS :

    641571-15-5

  • Molecular Formula : C28H22F3N7O

  • Molecular Weight : 529.52

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stdClass Object
(
    [pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
    [catalogue_number] => PA 14 64580
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 291.7
    [form] => C12H13ClF3N3
    [cas] => NA
    [pslug] => 3-4-ethyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-hydrochloride-pa1464580
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PA 14 64580
PA 14 64580

3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride

  • Catalogue No.:PA 14 64580

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3N3

  • Molecular Weight : 291.7

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stdClass Object
(
    [pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 64590
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 227.19
    [form] => C10H8F3N3
    [cas] => 943320-48-7
    [pslug] => 943320-48-7-3-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa1464590
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PA 14 64590
PA 14 64590

3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline

  • Catalogue No.:PA 14 64590

  • CAS :

    943320-48-7

  • Molecular Formula : C10H8F3N3

  • Molecular Weight : 227.19

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stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
    [catalogue_number] => PA STI 062190
    [category_ids] => ,79,80,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 244.23
    [form] => C11H7D3F3N3
    [cas] => 1246815-34-8
    [pslug] => 1246815-34-8-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethylaniline-d3-pasti062190
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PA STI 062190
PA STI 062190

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3

  • Catalogue No.:PA STI 062190

  • CAS :

    1246815-34-8

  • Molecular Formula : C11H7D3F3N3

  • Molecular Weight : 244.23

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