nilotinib
Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Nilotinib - Impurity C
[catalogue_number] => PA 14 64520
[category_ids] => 80,79,71
[chemical_name] =>
[weight] => 151.16
[form] => C8H9NO2
[cas] => 2458-12-0
[pslug] => 2458-12-0-nilotinib-impurity-c-pa1464520
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Catalogue No.:PA 14 64520
Molecular Formula : C8H9NO2
Molecular Weight : 151.16
stdClass Object
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[pname] => 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
[catalogue_number] => PA 14 64530
[category_ids] => ,79,80,70,84,
[chemical_name] =>
[weight] => 241.21
[form] => C11H10F3N3
[cas] => 641571-16-6
[pslug] => 641571-16-6-3-5-methyl-1h-imidazol-1-yl-5-trifluoromethyl-benzenamine-pa1464530
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3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
Catalogue No.:PA 14 64530
Molecular Formula : C11H10F3N3
Molecular Weight : 241.21
stdClass Object
(
[pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
[catalogue_number] => PA 14 64540
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 271.2
[form] => C11H8F3N3O2
[cas] => 916975-92-3
[pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540
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4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
stdClass Object
(
[pname] => Nilotinib - Impurity H (Hydrochloride Salt)
[catalogue_number] => PA 14 64550
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 565.98
[form] => C28H23ClF3N7O
[cas] => NA
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Nilotinib - Impurity H (Hydrochloride Salt)
Catalogue No.:PA 14 64550
Molecular Formula : C28H23ClF3N7O
Molecular Weight : 565.98
stdClass Object
(
[pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
[catalogue_number] => PA 14 64560
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 563.96
[form] => C28H21ClF3N7O
[cas] => NA
[pslug] => 3-4-chloro-6-pyridin-3-yl-pyrimidin-2-yl-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa1464560
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3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 64560
Molecular Formula : C28H21ClF3N7O
Molecular Weight : 563.96
stdClass Object
(
[pname] => Nilotinib - Impurity H (Freebase)
[catalogue_number] => PA 14 64570
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 529.52
[form] => C28H22F3N7O
[cas] => 641571-15-5
[pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570
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Nilotinib - Impurity H (Freebase)
Catalogue No.:PA 14 64570
Molecular Formula : C28H22F3N7O
Molecular Weight : 529.52
stdClass Object
(
[pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
[catalogue_number] => PA 14 64580
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 291.7
[form] => C12H13ClF3N3
[cas] => NA
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3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
stdClass Object
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[pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
[catalogue_number] => PA 14 64590
[category_ids] => ,80,71,70,78,82,75,79,89,
[chemical_name] =>
[weight] => 227.19
[form] => C10H8F3N3
[cas] => 943320-48-7
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3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 64590
Molecular Formula : C10H8F3N3
Molecular Weight : 227.19
stdClass Object
(
[pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
[catalogue_number] => PA STI 062190
[category_ids] => ,79,80,71,98,78,70,82,
[chemical_name] =>
[weight] => 244.23
[form] => C11H7D3F3N3
[cas] => 1246815-34-8
[pslug] => 1246815-34-8-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethylaniline-d3-pasti062190
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3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
Catalogue No.:PA STI 062190
Molecular Formula : C11H7D3F3N3
Molecular Weight : 244.23
