sofosbuvir
A recently approved nucleotide analog used in the treatment of hepatitis. Sofosbuvir works by inhibiting the hepatitis C NS5B protein. It is a a prodrug of its active antiviral agent GS-461203 Reference standards of Sofosbuvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Sofosbuvir
[catalogue_number] => PA 19 51000
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[chemical_name] =>
[weight] => 529.45
[form] => C22H29FN3O9P
[cas] => 1190307-88-0
[pslug] => 1190307-88-0-sofosbuvir-api-pa1951000
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Catalogue No.:PA 19 51000
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
stdClass Object
(
[pname] => Sofosbuvir Nucleoside Derivative
[catalogue_number] => PA 19 51510
[category_ids] => ,69,70,75,76,78,79,82,
[chemical_name] =>
[weight] => 260.22
[form] => C10H13FN2O5
[cas] => 863329-66-2
[pslug] => 863329-66-2-sofosbuvir-nucleoside-derivative-pa1951510
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Sofosbuvir Nucleoside Derivative
Catalogue No.:PA 19 51510
Molecular Formula : C10H13FN2O5
Molecular Weight : 260.22
stdClass Object
(
[pname] => Sofosbuvir Metabolite GS-566500
[catalogue_number] => PA 19 51520
[category_ids] => ,80,77,79,71,98,76,85,83,78,70,82,
[chemical_name] =>
[weight] => 411.28
[form] => C13H19FN3O9P
[cas] => 1233335-78-8
[pslug] => 1233335-78-8-sofosbuvir-metabolite-gs-566500-pa1951520
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Sofosbuvir Metabolite GS-566500
Catalogue No.:PA 19 51520
Molecular Formula : C13H19FN3O9P
Molecular Weight : 411.28
stdClass Object
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[catalogue_number] => PA 19 51530
[category_ids] => 85,83,82,80,79,78,77,76,71,70
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[weight] => 340.2
[form] => C10H14FN2O8P
[cas] => 1015073-43-4
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((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen Phosphate
stdClass Object
(
[pname] => N-(2-((Trimethylsilyl)oxy)pyrimidin-4-yl)benzamide
[catalogue_number] => PA 19 51550
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[chemical_name] =>
[weight] => 287.39
[form] => C14H17N3O2Si
[cas] => 85743-99-3
[pslug] => 85743-99-3-n-2-trimethylsilyl-oxy-pyrimidin-4-yl-benzamide-pa1951550
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N-(2-((Trimethylsilyl)oxy)pyrimidin-4-yl)benzamide
Catalogue No.:PA 19 51550
Molecular Formula : C14H17N3O2Si
Molecular Weight : 287.39
stdClass Object
(
[pname] => 1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
[catalogue_number] => PA 19 51660
[category_ids] => ,77,79,71,85,83,78,70,82,
[chemical_name] =>
[weight] => 276.67
[form] => C10H13ClN2O5
[cas] => 1496551-72-4
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1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 19 51660
Molecular Formula : C10H13ClN2O5
Molecular Weight : 276.67
stdClass Object
(
[pname] => (1R,2S)-1-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-3-ethoxy-2-fluoro-2-methyl-3-oxopropyl Sulfate
[catalogue_number] => PA 19 51670
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(1R,2S)-1-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-3-ethoxy-2-fluoro-2-methyl-3-oxopropyl Sulfate
Catalogue No.:PA 19 51670
Molecular Formula : C11H19FO8S
Molecular Weight : 330.33
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(
[pname] => (4S,5R)-Ethyl 5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide
[catalogue_number] => PA 19 51680
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(4S,5R)-Ethyl 5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide
Catalogue No.:PA 19 51680
Molecular Formula : C11H18O8S
Molecular Weight : 310.32
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[pname] => (2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
[catalogue_number] => PA 19 51690
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[weight] => 248.27
[form] => C11H20O6
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(2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
Catalogue No.:PA 19 51690
Molecular Formula : C11H20O6
Molecular Weight : 248.27
stdClass Object
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[pname] => (S,E)-Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylacrylate
[catalogue_number] => PA 19 51700
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[chemical_name] =>
[weight] => 214.26
[form] => C11H18O4
[cas] => 81997-76-4
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(S,E)-Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylacrylate
Catalogue No.:PA 19 51700
Molecular Formula : C11H18O4
Molecular Weight : 214.26
stdClass Object
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[pname] => (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde
[catalogue_number] => PA 19 51710
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[chemical_name] =>
[weight] => 130.14
[form] => C6H10O3
[cas] => 15186-48-8
[pslug] => 15186-48-8-r-2-2-dimethyl-1-3-dioxolane-4-carbaldehyde-pa1951710
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(R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde
Catalogue No.:PA 19 51710
Molecular Formula : C6H10O3
Molecular Weight : 130.14
stdClass Object
(
[pname] => Chloro Sofosbuvir
[catalogue_number] => PA 19 51820
[category_ids] => ,79,80,71,76,75,85,83,78,70,82,72,
[chemical_name] =>
[weight] => 545.91
[form] => C22H29ClN3O9P
[cas] => 1496552-51-2
[pslug] => 1496552-51-2-chloro-sofosbuvir-pa1951820
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Catalogue No.:PA 19 51820
Molecular Formula : C22H29ClN3O9P
Molecular Weight : 545.91
stdClass Object
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[pname] => (S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;
[catalogue_number] => PA 19 51900
[category_ids] => ,80,79,75,78,70,82,
[chemical_name] =>
[weight] => 515.43
[form] => C21H27FN3O9P
[cas] => 2164516-85-0
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(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;
Catalogue No.:PA 19 51900
Molecular Formula : C21H27FN3O9P
Molecular Weight : 515.43
stdClass Object
(
[pname] => Methyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 0511016
[category_ids] => ,79,71,78,70,82,
[chemical_name] =>
[weight] => 501.4
[form] => C20H25FN3O9P
[cas] => 1394157-34-6
[pslug] => 1394157-34-6-methyl-s-2r-3r-4r-5r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl-methoxy-phenoxy-phosphoryl-l-alaninate-pa190511016
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Methyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
stdClass Object
(
[pname] => Isopropyl ((((3S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
[catalogue_number] => PA 19 0511018
[category_ids] => ,80,77,79,71,98,85,83,78,70,82,
[chemical_name] =>
[weight] => 529.46
[form] => C22H29FN3O9P
[cas] => 2766447-19-0
[pslug] => 2766447-19-0-isopropyl-3s-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl-methoxy-phenoxy-phosphoryl-d-alaninate-pa190511018
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Isopropyl ((((3S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511018
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.46
stdClass Object
(
[pname] => Isopropyl ((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 0511019
[category_ids] => ,80,77,79,71,98,85,83,78,70,82,
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[weight] => 528.47
[form] => C22H30FN4O8P
[cas] => 1334513-10-8
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Isopropyl ((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511019
Molecular Formula : C22H30FN4O8P
Molecular Weight : 528.47
stdClass Object
(
[pname] => Isopropyl ((S)-((S)-1-((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)ethoxy)(phenoxy)phosphoryl)-L-alaninate
[catalogue_number] => PA 19 0511020
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[chemical_name] =>
[weight] => 541.49
[form] => C23H32N3O10P
[cas] => 2500766-09-4
[pslug] => 2500766-09-4-isopropyl-s-s-1-2s-3r-4r-5r-5-2-4-dioxo-3-4-dihydropyrimidin-1-2h-yl-3-4-dihydroxy-4-methyltetrahydrofuran-2-yl-ethoxy-phenoxy-phosphoryl-l-alaninate-pa190511020
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Isopropyl ((S)-((S)-1-((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)ethoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511020
Molecular Formula : C23H32N3O10P
Molecular Weight : 541.49
