Sorafenib Tosilate
A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib Tosylate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[form] => C28H24ClF3N4O6S
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Sorafenib Tosilate - API Standards
Catalogue No.:PA 19 69000
Molecular Formula : C28H24ClF3N4O6S
Molecular Weight : 637.03
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Sorafenib Tosilate - Impurity H
Catalogue No.:PA 19 69530
Molecular Formula : C21H16ClF3N4O3
Molecular Weight : 464.82
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Sorafenib Tosilate - Impurity E
Catalogue No.:PA 46 17560
Molecular Formula : C27H24N6O5
Molecular Weight : 512.52
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Sorafenib Tosilate - Impurity F
Catalogue No.:PA 46 17570
Molecular Formula : C21H17F3N4O3
Molecular Weight : 430.38
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Sorafenib Tosilate - Impurity D
Catalogue No.:PA 46 17550
Molecular Formula : C17H19N3O4
Molecular Weight : 329.35