trametinib
Trametinib may be used alone or in combination with another medication to treat a type of skin cancer. It is a MEK inhibitor drug with anti-cancer activity.Reference standards of Trametinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => N-(3-(5-((4-Bromo-2-fluorophenyl)amino)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide
[catalogue_number] => PA 47 14510
[category_ids] => ,80,78,70,82,79,89,
[chemical_name] =>
[weight] => 568.39
[form] => C26H23BrFN5O4
[cas] => 871700-13-9
[pslug] => 871700-13-9-n-3-5-4-bromo-2-fluorophenyl-amino-3-cyclopropyl-6-8-dimethyl-2-4-7-trioxo-3-4-6-7-tetrahydropyrido-4-3-d-pyrimidin-1-2h-yl-phenyl-acetamide-pa4714510
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N-(3-(5-((4-Bromo-2-fluorophenyl)amino)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide
Catalogue No.:PA 47 14510
Molecular Formula : C26H23BrFN5O4
Molecular Weight : 568.39
stdClass Object
(
[pname] => 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione
[catalogue_number] => PA 47 14520
[category_ids] => ,78,70,82,89,79,80,
[chemical_name] =>
[weight] => 401.17
[form] => C14H13FIN3O2
[cas] => 871700-22-0
[pslug] => 871700-22-0-3-cyclopropyl-1-2-fluoro-4-iodophenyl-6-methylamino-pyrimidine-2-4-1h-3h-dione-pa4714520
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3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 47 14520
Molecular Formula : C14H13FIN3O2
Molecular Weight : 401.17
stdClass Object
(
[pname] => Trametinib-d4
[catalogue_number] => PA STI 084082
[category_ids] => ,79,80,71,78,70,82,98,
[chemical_name] =>
[weight] => 619.42
[form] => C26H19D4FIN5O4
[cas] => NA
[pslug] => trametinib-d4-pasti084082
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Catalogue No.:PA STI 084082
Molecular Formula : C26H19D4FIN5O4
Molecular Weight : 619.42
