dolutegravir

Antiviral agents - Dolutegravir is a HIV-1 intergrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell.. Reference standards of Dolutegravir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Dolutegravir
    [catalogue_number] => PA 04 95000
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 419.38
    [form] => C20H19F2N3O5
    [cas] => 1051375-16-6
    [pslug] => 1051375-16-6-dolutegravir-api-pa0495000
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PA 04 95000
PA 04 95000

Dolutegravir


  • Catalogue No.:PA 04 95000

  • CAS :

    1051375-16-6

  • Molecular Formula : C20H19F2N3O5

  • Molecular Weight : 419.38

stdClass Object
(
    [pname] => 4-Fluoro Dolutegravir
    [catalogue_number] => PA 04 95510
    [category_ids] => ,70,71,77,78,80,81,82,
    [chemical_name] => 
    [weight] => 401.39
    [form] => C20H20FN3O5
    [cas] => 1863916-88-4
    [pslug] => 1863916-88-4-4-fluoro-dolutegravir-pa0495510
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PA 04 95510
PA 04 95510

4-Fluoro Dolutegravir


  • Catalogue No.:PA 04 95510

  • CAS :

    1863916-88-4

  • Molecular Formula : C20H20FN3O5

  • Molecular Weight : 401.39

stdClass Object
(
    [pname] => 2-Fluoro Dolutegravir
    [catalogue_number] => PA 04 95520
    [category_ids] => ,71,70,78,82,80,77,81,
    [chemical_name] => 
    [weight] => 401.39
    [form] => C20H20FN3O5
    [cas] => 1863916-87-3
    [pslug] => 1863916-87-3-2-fluoro-dolutegravir-pa0495520
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PA 04 95520
PA 04 95520

2-Fluoro Dolutegravir


  • Catalogue No.:PA 04 95520

  • CAS :

    1863916-87-3

  • Molecular Formula : C20H20FN3O5

  • Molecular Weight : 401.39

stdClass Object
(
    [pname] => Dolutegravir Diastereomer Sodium Salt
    [catalogue_number] => PA 04 95530
    [category_ids] => ,81,77,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 441.36
    [form] => C20H18F2N3NaO5
    [cas] => 1809261-48-0
    [pslug] => 1809261-48-0-dolutegravir-diastereomer-sodium-salt-pa0495530
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PA 04 95530
PA 04 95530

Dolutegravir Diastereomer Sodium Salt


  • Catalogue No.:PA 04 95530

  • CAS :

    1809261-48-0

  • Molecular Formula : C20H18F2N3NaO5

  • Molecular Weight : 441.36

stdClass Object
(
    [pname] => Dolutegravir RR Isomer
    [catalogue_number] => PA 04 95540
    [category_ids] => ,81,77,80,82,78,70,71,
    [chemical_name] => 
    [weight] => 419.38
    [form] => C20H19F2N3O5
    [cas] => 1357289-29-2
    [pslug] => 1357289-29-2-dolutegravir-rr-isomer-pa0495540
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PA 04 95540
PA 04 95540

Dolutegravir RR Isomer


  • Catalogue No.:PA 04 95540

  • CAS :

    1357289-29-2

  • Molecular Formula : C20H19F2N3O5

  • Molecular Weight : 419.38

stdClass Object
(
    [pname] => Dolutegravir O-beta-D-Glucuronide
    [catalogue_number] => PA 04 0951035
    [category_ids] => ,70,71,77,78,80,81,82,95,
    [chemical_name] => 
    [weight] => 595.51
    [form] => C26H27F2N3O11
    [cas] => 1485692-21-4
    [pslug] => 1485692-21-4-dolutegravir-o-beta-d-glucuronide-pa040951035
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PA 04 0951035
PA 04 0951035

Dolutegravir O-beta-D-Glucuronide


  • Catalogue No.:PA 04 0951035

  • CAS :

    1485692-21-4

  • Molecular Formula : C26H27F2N3O11

  • Molecular Weight : 595.51

stdClass Object
(
    [pname] => (R)-3-(7-((2,4-Difluorobenzyl)carbamoyl)-9-hydroxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-2-yl)butyl (2,4-difluorobenzyl)carbamate
    [catalogue_number] => PA 04 0951039
    [category_ids] => ,81,80,77,71,70,78,82,
    [chemical_name] => 
    [weight] => 588.52
    [form] => C28H24F4N4O6
    [cas] => 2244161-73-5
    [pslug] => 2244161-73-5-r-3-7-2-4-difluorobenzyl-carbamoyl-9-hydroxy-1-8-dioxo-1-8-dihydro-2h-pyrido-1-2-a-pyrazin-2-yl-butyl-2-4-difluorobenzyl-carbamate-pa040951039
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PA 04 0951039
PA 04 0951039

(R)-3-(7-((2,4-Difluorobenzyl)carbamoyl)-9-hydroxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-2-yl)butyl (2,4-difluorobenzyl)carbamate


  • Catalogue No.:PA 04 0951039

  • CAS :

    2244161-73-5

  • Molecular Formula : C28H24F4N4O6

  • Molecular Weight : 588.52

stdClass Object
(
    [pname] => Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate
    [catalogue_number] => PA 04 0951040
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 322.32
    [form] => C15H18N2O6
    [cas] => 2677842-37-2
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PA 04 0951040
PA 04 0951040

Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate


  • Catalogue No.:PA 04 0951040

  • CAS :

    2677842-37-2

  • Molecular Formula : C15H18N2O6

  • Molecular Weight : 322.32

stdClass Object
(
    [pname] => (R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
    [catalogue_number] => PA 04 0951041
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 294.26
    [form] => C13H14N2O6
    [cas] => 3028615-32-6
    [pslug] => 3028615-32-6-r-9-hydroxy-2-4-hydroxybutan-2-yl-1-8-dioxo-1-8-dihydro-2h-pyrido-1-2-a-pyrazine-7-carboxylic-acid-pa040951041
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PA 04 0951041
PA 04 0951041

(R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid


  • Catalogue No.:PA 04 0951041

  • CAS :

    3028615-32-6

  • Molecular Formula : C13H14N2O6

  • Molecular Weight : 294.26

stdClass Object
(
    [pname] => 1,3-Bis(2,4-difluorobenzyl)urea
    [catalogue_number] => PA 04 0951042
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 312.27
    [form] => C15H12F4N2O
    [cas] => NA
    [pslug] => 1-3-bis-2-4-difluorobenzyl-urea-pa040951042
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PA 04 0951042
PA 04 0951042

1,3-Bis(2,4-difluorobenzyl)urea


  • Catalogue No.:PA 04 0951042

  • CAS :

    NA

  • Molecular Formula : C15H12F4N2O

  • Molecular Weight : 312.27

stdClass Object
(
    [pname] => (4R,12aS)-N-(4-((2,4-Difluorobenzyl)amino)-2-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
    [catalogue_number] => PA 04 0951047
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 556.54
    [form] => C28H27F3N4O5
    [cas] => 2767197-74-8
    [pslug] => 2767197-74-8-4r-12as-n-4-2-4-difluorobenzyl-amino-2-fluorobenzyl-7-methoxy-4-methyl-6-8-dioxo-3-4-6-8-12-12a-hexahydro-2h-pyrido-1-2-4-5-pyrazino-2-1-b-1-3-oxazine-9-carboxamide-pa040951047
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PA 04 0951047
PA 04 0951047

(4R,12aS)-N-(4-((2,4-Difluorobenzyl)amino)-2-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide


  • Catalogue No.:PA 04 0951047

  • CAS :

    2767197-74-8

  • Molecular Formula : C28H27F3N4O5

  • Molecular Weight : 556.54

stdClass Object
(
    [pname] => 5-((2,4-Difluorobenzyl)carbamoyl)-3-hydroxy-1-((4-methyl-1,3-oxazinan-2-yl)methyl)-4-oxo-1,4-dihydropyridine-2-carboxylic Acid
    [catalogue_number] => PA 04 0951048
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 437.4
    [form] => C20H21F2N3O6
    [cas] => 1800247-07-7
    [pslug] => 1800247-07-7-5-2-4-difluorobenzyl-carbamoyl-3-hydroxy-1-4-methyl-1-3-oxazinan-2-yl-methyl-4-oxo-1-4-dihydropyridine-2-carboxylic-acid-pa040951048
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PA 04 0951048
PA 04 0951048

5-((2,4-Difluorobenzyl)carbamoyl)-3-hydroxy-1-((4-methyl-1,3-oxazinan-2-yl)methyl)-4-oxo-1,4-dihydropyridine-2-carboxylic Acid


  • Catalogue No.:PA 04 0951048

  • CAS :

    1800247-07-7

  • Molecular Formula : C20H21F2N3O6

  • Molecular Weight : 437.4

stdClass Object
(
    [pname] => (R)-9-Ethoxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid
    [catalogue_number] => PA 04 0951052
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 322.32
    [form] => C15H18N2O6
    [cas] => NA
    [pslug] => r-9-ethoxy-2-4-hydroxybutan-2-yl-1-8-dioxo-1-8-dihydro-2h-pyrido-1-2-a-pyrazine-7-carboxylic-acid-pa040951052
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PA 04 0951052
PA 04 0951052

(R)-9-Ethoxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid


  • Catalogue No.:PA 04 0951052

  • CAS :

    NA

  • Molecular Formula : C15H18N2O6

  • Molecular Weight : 322.32

stdClass Object
(
    [pname] => Dolutegravir acid impuirty
    [catalogue_number] => PA 04 0951053
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 294.26
    [form] => C13H14N2O6
    [cas] => NA
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PA 04 0951053
PA 04 0951053

Dolutegravir acid impuirty


  • Catalogue No.:PA 04 0951053

  • CAS :

    NA

  • Molecular Formula : C13H14N2O6

  • Molecular Weight : 294.26

stdClass Object
(
    [pname] => (4R,12aS)-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
    [catalogue_number] => PA 04 0951054
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H14N2O5
    [cas] => 1623085-80-2
    [pslug] => 1623085-80-2-4r-12as-4-methyl-6-8-dioxo-3-4-6-8-12-12a-hexahydro-2h-pyrido-1-2-4-5-pyrazino-2-1-b-1-3-oxazine-9-carboxylic-acid-pa040951054
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PA 04 0951054
PA 04 0951054

(4R,12aS)-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid


  • Catalogue No.:PA 04 0951054

  • CAS :

    1623085-80-2

  • Molecular Formula : C13H14N2O5

  • Molecular Weight : 278.26

stdClass Object
(
    [pname] => Dolutegravir Hydroxy Impurity
    [catalogue_number] => PA 04 0951055
    [category_ids] => ,77,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 435.38
    [form] => C20H19F2N3O6
    [cas] => NA
    [pslug] => dolutegravir-hydroxy-impurity-pa040951055
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PA 04 0951055
PA 04 0951055

Dolutegravir Hydroxy Impurity


  • Catalogue No.:PA 04 0951055

  • CAS :

    NA

  • Molecular Formula : C20H19F2N3O6

  • Molecular Weight : 435.38

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