bendamustine hydrochloride

Aromatics - An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Bendamustine Nitro Ethyl Ester
    [catalogue_number] => PA 02 07580
    [category_ids] => ,80,71,70,
    [chemical_name] => 
    [weight] => 291.31
    [form] => C14H17N3O4
    [cas] => 3543-72-4
    [pslug] => 3543-72-4-bendamustine-nitro-ethyl-ester-pa0207580
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PA 02 07580
PA 02 07580

Bendamustine Nitro Ethyl Ester


  • Catalogue No.:PA 02 07580

  • CAS :

    3543-72-4

  • Molecular Formula : C14H17N3O4

  • Molecular Weight : 291.31

stdClass Object
(
    [pname] => Hydroxy Bendamustine
    [catalogue_number] => PA 02 07590
    [category_ids] => ,70,71,80,
    [chemical_name] => 
    [weight] => 339.82
    [form] => C16H22ClN3O3
    [cas] => 109882-27-1
    [pslug] => 109882-27-1-hydroxy-bendamustine-pa0207590
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PA 02 07590
PA 02 07590

Hydroxy Bendamustine


  • Catalogue No.:PA 02 07590

  • CAS :

    109882-27-1

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

stdClass Object
(
    [pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07610
    [category_ids] => ,70,71,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 353.87
    [form] => C16H20ClN3O2S
    [cas] => 191939-34-1
    [pslug] => 191939-34-1-4-6-2-chloroethyl-3-methyl-3-6-7-8-tetrahydroimidazo-4-5-5-6-benzo-1-2-b-1-4-thiazin-2-yl-butanoic-acid-pa0207610
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PA 02 07610
PA 02 07610

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07610

  • CAS :

    191939-34-1

  • Molecular Formula : C16H20ClN3O2S

  • Molecular Weight : 353.87

stdClass Object
(
    [pname] => Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate
    [catalogue_number] => PA 02 07620
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 305.33
    [form] => C15H19N3O4
    [cas] => 1374784-01-6
    [pslug] => 1374784-01-6-isopropyl-4-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-butanoate-pa0207620
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PA 02 07620
PA 02 07620

Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate


  • Catalogue No.:PA 02 07620

  • CAS :

    1374784-01-6

  • Molecular Formula : C15H19N3O4

  • Molecular Weight : 305.33

stdClass Object
(
    [pname] => 1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane
    [catalogue_number] => PA 02 07630
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 394.38
    [form] => C19H18N6O4
    [cas] => 914626-65-6
    [pslug] => 914626-65-6-1-3-bis-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-propane-pa0207630
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PA 02 07630
PA 02 07630

1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane


  • Catalogue No.:PA 02 07630

  • CAS :

    914626-65-6

  • Molecular Formula : C19H18N6O4

  • Molecular Weight : 394.38

stdClass Object
(
    [pname] => N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide
    [catalogue_number] => PA 02 07640
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 430.41
    [form] => C19H22N6O6
    [cas] => NA
    [pslug] => n1-n5-bis-2-methylamino-5-nitrophenyl-glutaramide-pa0207640
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PA 02 07640
PA 02 07640

N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide


  • Catalogue No.:PA 02 07640

  • CAS :

    NA

  • Molecular Formula : C19H22N6O6

  • Molecular Weight : 430.41

stdClass Object
(
    [pname] => 2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)
    [catalogue_number] => PA 02 07650
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 334.42
    [form] => C19H22N6
    [cas] => 847588-86-7
    [pslug] => 847588-86-7-2-2-propane-1-3-diyl-bis-1-methyl-1h-benzo-d-imidazol-5-amine-pa0207650
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PA 02 07650
PA 02 07650

2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)


  • Catalogue No.:PA 02 07650

  • CAS :

    847588-86-7

  • Molecular Formula : C19H22N6

  • Molecular Weight : 334.42

stdClass Object
(
    [pname] => 2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07660
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 432.34
    [form] => C19H27Cl2N3O4
    [cas] => NA
    [pslug] => 2-3-dihydroxypropyl-4-5-bis-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207660
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PA 02 07660
PA 02 07660

2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07660

  • CAS :

    NA

  • Molecular Formula : C19H27Cl2N3O4

  • Molecular Weight : 432.34

stdClass Object
(
    [pname] => 4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07670
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 381.85
    [form] => C18H24ClN3O4
    [cas] => NA
    [pslug] => 4-5-2-acetoxyethyl-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa0207670
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PA 02 07670
PA 02 07670

4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07670

  • CAS :

    NA

  • Molecular Formula : C18H24ClN3O4

  • Molecular Weight : 381.85

stdClass Object
(
    [pname] => Deschloroethyl Bendamustine
    [catalogue_number] => PA 02 07680
    [category_ids] => ,70,78,80,82,98,
    [chemical_name] => 
    [weight] => 295.76
    [form] => C14H18ClN3O2
    [cas] => 1219709-86-0
    [pslug] => 1219709-86-0-deschloroethyl-bendamustine-pa0207680
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PA 02 07680
PA 02 07680

Deschloroethyl Bendamustine


  • Catalogue No.:PA 02 07680

  • CAS :

    1219709-86-0

  • Molecular Formula : C14H18ClN3O2

  • Molecular Weight : 295.76

stdClass Object
(
    [pname] => Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07690
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 335.4
    [form] => C17H25N3O4
    [cas] => 109882-31-7
    [pslug] => 109882-31-7-methyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207690
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PA 02 07690
PA 02 07690

Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07690

  • CAS :

    109882-31-7

  • Molecular Formula : C17H25N3O4

  • Molecular Weight : 335.4

stdClass Object
(
    [pname] => 2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07700
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 666.81
    [form] => C35H50N6O7
    [cas] => NA
    [pslug] => 2-2-hydroxyethyl-2-4-isopropoxy-4-oxobutyl-1-methyl-1h-benzo-d-imidazol-5-yl-amino-ethyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207700
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PA 02 07700
PA 02 07700

2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07700

  • CAS :

    NA

  • Molecular Formula : C35H50N6O7

  • Molecular Weight : 666.81

stdClass Object
(
    [pname] => N-Methyl-2-amino-4-nitroaniline
    [catalogue_number] => PA 02 07770
    [category_ids] => ,79,80,
    [chemical_name] => 
    [weight] => 167.17
    [form] => C7H9N3O2
    [cas] => 41939-61-1
    [pslug] => 41939-61-1-n-methyl-2-amino-4-nitroaniline-pa0207770
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PA 02 07770
PA 02 07770

N-Methyl-2-amino-4-nitroaniline


  • Catalogue No.:PA 02 07770

  • CAS :

    41939-61-1

  • Molecular Formula : C7H9N3O2

  • Molecular Weight : 167.17

stdClass Object
(
    [pname] => Bendamustine Dihydroxy
    [catalogue_number] => PA 02 07810
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 357.84
    [form] => C16H24ClN3O4
    [cas] => 109882-29-3
    [pslug] => 109882-29-3-bendamustine-dihydroxy-pa0207810
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PA 02 07810
PA 02 07810

Bendamustine Dihydroxy


  • Catalogue No.:PA 02 07810

  • CAS :

    109882-29-3

  • Molecular Formula : C16H24ClN3O4

  • Molecular Weight : 357.84

stdClass Object
(
    [pname] => Bendamustine Ether  Hydrochloride Impurity
    [catalogue_number] => PA 02 07820
    [category_ids] => ,82,80,78,70,
    [chemical_name] => 
    [weight] => 339.82
    [form] => C16H22ClN3O3
    [cas] => 2173004-95-8
    [pslug] => 2173004-95-8-bendamustine-ether-hydrochloride-impurity-pa0207820
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PA 02 07820
PA 02 07820

Bendamustine Ether Hydrochloride Impurity


  • Catalogue No.:PA 02 07820

  • CAS :

    2173004-95-8

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

stdClass Object
(
    [pname] => Bendamustine Mannitol Ester
    [catalogue_number] => PA 02 07840
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 522.42
    [form] => C22H33Cl2N3O7
    [cas] => 1869075-89-7
    [pslug] => 1869075-89-7-bendamustine-mannitol-ester-pa0207840
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PA 02 07840
PA 02 07840

Bendamustine Mannitol Ester


  • Catalogue No.:PA 02 07840

  • CAS :

    1869075-89-7

  • Molecular Formula : C22H33Cl2N3O7

  • Molecular Weight : 522.42

stdClass Object
(
    [pname] => 5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid
    [catalogue_number] => PA 02 07850
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 374.26
    [form] => C16H21Cl2N3O3
    [cas] => 1138238-08-0
    [pslug] => 1138238-08-0-5-bis-2-chloroethyl-amino-gamma-hydroxy-1-methyl-1h-benzimidazole-2-butanoic-acid-pa0207850
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PA 02 07850
PA 02 07850

5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid


  • Catalogue No.:PA 02 07850

  • CAS :

    1138238-08-0

  • Molecular Formula : C16H21Cl2N3O3

  • Molecular Weight : 374.26

stdClass Object
(
    [pname] => N-Desmethylbendamustine
    [catalogue_number] => PA 02 07860
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 344.24
    [form] => C15H19Cl2N3O2
    [cas] => 41515-13-3
    [pslug] => 41515-13-3-n-desmethylbendamustine-pa0207860
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PA 02 07860
PA 02 07860

N-Desmethylbendamustine


  • Catalogue No.:PA 02 07860

  • CAS :

    41515-13-3

  • Molecular Formula : C15H19Cl2N3O2

  • Molecular Weight : 344.24

stdClass Object
(
    [pname] => [1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester
    [catalogue_number] => PA 02 07830
    [category_ids] => ,82,80,78,70,
    [chemical_name] => 
    [weight] => 349.43
    [form] => C18H27N3O4
    [cas] => 3543-74-6
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PA 02 07830
PA 02 07830

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester


  • Catalogue No.:PA 02 07830

  • CAS :

    3543-74-6

  • Molecular Formula : C18H27N3O4

  • Molecular Weight : 349.43

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