Bosutinib-impurities | Pharmaffiliates

bosutinib

Bosutinib is used to treat chronic myeloid leukaemia that has an abnormal chromosome called the Philadelphia chromosome. It is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.. Reference standards of Bosutinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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(
    [pname] => Bosutinib - API Standards 
    [catalogue_number] => PA 02 92000
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 530.45
    [form] => C26H29Cl2N5O3
    [cas] => 380843-75-4
    [pslug] => 380843-75-4-bosutinib-api-pa0292000
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PA 02 92000

Bosutinib - API Standards


  • Catalogue No.:PA 02 92000

  • CAS :

    380843-75-4

  • Molecular Formula : C26H29Cl2N5O3

  • Molecular Weight : 530.45

stdClass Object
(
    [pname] => 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(piperazin-1-yl)propoxy)quinoline-3-carbonitrile
    [catalogue_number] => PA 02 92540
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 516.42
    [form] => C25H27Cl2N5O3
    [cas] => 380843-81-2
    [pslug] => 380843-81-2-4-2-4-dichloro-5-methoxyphenyl-amino-6-methoxy-7-3-piperazin-1-yl-propoxy-quinoline-3-carbonitrile-pa0292540
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PA 02 92540

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(piperazin-1-yl)propoxy)quinoline-3-carbonitrile


  • Catalogue No.:PA 02 92540

  • CAS :

    380843-81-2

  • Molecular Formula : C25H27Cl2N5O3

  • Molecular Weight : 516.42

20% OFF
stdClass Object
(
    [pname] => 4-((3,5-Dichloro-4-methoxyphenyl)amino)-6-methoxy-7-(3-(1-methylpiperidin-4-yl)propoxy)quinoline-3-carbonitrile
    [catalogue_number] => PA 02 92510
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 529.46
    [form] => C27H30Cl2N4O3
    [cas] => NA
    [pslug] => 4-3-5-dichloro-4-methoxyphenyl-amino-6-methoxy-7-3-1-methylpiperidin-4-yl-propoxy-quinoline-3-carbonitrile-pa0292510
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PA 02 92510

4-((3,5-Dichloro-4-methoxyphenyl)amino)-6-methoxy-7-(3-(1-methylpiperidin-4-yl)propoxy)quinoline-3-carbonitrile


  • Catalogue No.:PA 02 92510

  • CAS :

    NA

  • Molecular Formula : C27H30Cl2N4O3

  • Molecular Weight : 529.46

stdClass Object
(
    [pname] => Bosutinib Chloro Impurity
    [catalogue_number] => PA 02 92530
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 374.86
    [form] => C19H23ClN4O2
    [cas] => 492444-39-0
    [pslug] => 492444-39-0-bosutinib-chloro-impurity-pa0292530
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PA 02 92530

Bosutinib Chloro Impurity


  • Catalogue No.:PA 02 92530

  • CAS :

    492444-39-0

  • Molecular Formula : C19H23ClN4O2

  • Molecular Weight : 374.86

stdClass Object
(
    [pname] => 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile
    [catalogue_number] => PA 02 92550
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 390.22
    [form] => C18H13Cl2N3O3
    [cas] => 1460227-29-5
    [pslug] => 1460227-29-5-4-2-4-dichloro-5-methoxyphenyl-amino-7-hydroxy-6-methoxy-3-quinolinecarbonitrile-pa0292550
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PA 02 92550

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile


  • Catalogue No.:PA 02 92550

  • CAS :

    1460227-29-5

  • Molecular Formula : C18H13Cl2N3O3

  • Molecular Weight : 390.22

stdClass Object
(
    [pname] => 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile
    [catalogue_number] => PA 02 92560
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 404.25
    [form] => C19H15Cl2N3O3
    [cas] => 380843-12-9
    [pslug] => 380843-12-9-4-2-4-dichloro-5-methoxyphenyl-amino-6-7-dimethoxy-3-quinolinecarbonitrile-pa0292560
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PA 02 92560

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile


  • Catalogue No.:PA 02 92560

  • CAS :

    380843-12-9

  • Molecular Formula : C19H15Cl2N3O3

  • Molecular Weight : 404.25

stdClass Object
(
    [pname] => N-Desmethylpiperazine Hydroxy Bosutinib
    [catalogue_number] => PA 02 92570
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 448.3
    [form] => C21H19Cl2N3O4
    [cas] => NA
    [pslug] => n-desmethylpiperazine-hydroxy-bosutinib-pa0292570
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PA 02 92570

N-Desmethylpiperazine Hydroxy Bosutinib


  • Catalogue No.:PA 02 92570

  • CAS :

    NA

  • Molecular Formula : C21H19Cl2N3O4

  • Molecular Weight : 448.3

stdClass Object
(
    [pname] => 7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyanilino)-6-methoxyquinoline-3-carbonitrile
    [catalogue_number] => PA 02 92580
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 466.74
    [form] => C21H18Cl3N3O3
    [cas] => 380844-49-5
    [pslug] => 380844-49-5-7-3-chloropropoxy-4-2-4-dichloro-5-methoxyanilino-6-methoxyquinoline-3-carbonitrile-pa0292580
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PA 02 92580

7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyanilino)-6-methoxyquinoline-3-carbonitrile


  • Catalogue No.:PA 02 92580

  • CAS :

    380844-49-5

  • Molecular Formula : C21H18Cl3N3O3

  • Molecular Weight : 466.74

stdClass Object
(
    [pname] => Methyl 4-(3-chloropropoxy)-3-methoxybenzoate
    [catalogue_number] => PA 02 92590
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 258.7
    [form] =>  C12H15ClO4
    [cas] => 111627-40-8
    [pslug] => 111627-40-8-methyl-4-3-chloropropoxy-3-methoxybenzoate-pa0292590
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PA 02 92590

Methyl 4-(3-chloropropoxy)-3-methoxybenzoate


  • Catalogue No.:PA 02 92590

  • CAS :

    111627-40-8

  • Molecular Formula : C12H15ClO4

  • Molecular Weight : 258.7

stdClass Object
(
    [pname] => 2-Bromo-4-(3-chloropropoxy)-5-methoxybenzoic Acid
    [catalogue_number] => PA 02 92600
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 323.57
    [form] => C11H12BrClO4
    [cas] => NA
    [pslug] => 2-bromo-4-3-chloropropoxy-5-methoxybenzoic-acid-pa0292600
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PA 02 92600

2-Bromo-4-(3-chloropropoxy)-5-methoxybenzoic Acid


  • Catalogue No.:PA 02 92600

  • CAS :

    NA

  • Molecular Formula : C11H12BrClO4

  • Molecular Weight : 323.57

stdClass Object
(
    [pname] => (Z)-Ethyl 3-(2-bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-2-cyano-3-hydroxyacrylate
    [catalogue_number] => PA 02 92610
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 418.67
    [form] => C16H17BrClNO5
    [cas] => NA
    [pslug] => z-ethyl-3-2-bromo-4-3-chloropropoxy-5-methoxyphenyl-2-cyano-3-hydroxyacrylate-pa0292610
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PA 02 92610

(Z)-Ethyl 3-(2-bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-2-cyano-3-hydroxyacrylate


  • Catalogue No.:PA 02 92610

  • CAS :

    NA

  • Molecular Formula : C16H17BrClNO5

  • Molecular Weight : 418.67

stdClass Object
(
    [pname] => (E)-3-(2-Bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-3-hydroxyacrylonitrile
    [catalogue_number] => PA 02 92620
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 346.6
    [form] => C13H13BrClNO3
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PA 02 92620

(E)-3-(2-Bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-3-hydroxyacrylonitrile


  • Catalogue No.:PA 02 92620

  • CAS :

    NA

  • Molecular Formula : C13H13BrClNO3

  • Molecular Weight : 346.6

stdClass Object
(
    [pname] => (E)-3-Amino-2-(2-bromo-4-(3-chloropropoxy)-5-methoxybenzoyl)acrylonitrile
    [catalogue_number] => PA 02 92630
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 373.63
    [form] => C14H14BrClN2O3
    [cas] => NA
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PA 02 92630

(E)-3-Amino-2-(2-bromo-4-(3-chloropropoxy)-5-methoxybenzoyl)acrylonitrile


  • Catalogue No.:PA 02 92630

  • CAS :

    NA

  • Molecular Formula : C14H14BrClN2O3

  • Molecular Weight : 373.63

stdClass Object
(
    [pname] => Methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate
    [catalogue_number] => PA 02 92650
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 303.7
    [form] => C12H14ClNO6
    [cas] => 214470-57-2
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PA 02 92650

Methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate


  • Catalogue No.:PA 02 92650

  • CAS :

    214470-57-2

  • Molecular Formula : C12H14ClNO6

  • Molecular Weight : 303.7

stdClass Object
(
    [pname] => Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate
    [catalogue_number] => PA 02 92660
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 273.71
    [form] => C12H16ClNO4
    [cas] => 214470-59-4
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PA 02 92660

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate


  • Catalogue No.:PA 02 92660

  • CAS :

    214470-59-4

  • Molecular Formula : C12H16ClNO4

  • Molecular Weight : 273.71

stdClass Object
(
    [pname] => (E)-Methyl 4-(3-chloropropoxy)-2-((2-cyanovinyl)amino)-5-methoxybenzoate
    [catalogue_number] => PA 02 92670
    [category_ids] => ,80,79,84,
    [chemical_name] => 
    [weight] => 324.76
    [form] => C15H17ClN2O4
    [cas] => NA
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PA 02 92670

(E)-Methyl 4-(3-chloropropoxy)-2-((2-cyanovinyl)amino)-5-methoxybenzoate


  • Catalogue No.:PA 02 92670

  • CAS :

    NA

  • Molecular Formula : C15H17ClN2O4

  • Molecular Weight : 324.76

stdClass Object
(
    [pname] => 2-Cyano-N-(2,4-Dichloro-5-Methoxyphenyl)Acetamide
    [catalogue_number] => PA 02 92680
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 259.09
    [form] => C10H8Cl2N2O2
    [cas] => 846023-24-3
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PA 02 92680

2-Cyano-N-(2,4-Dichloro-5-Methoxyphenyl)Acetamide


  • Catalogue No.:PA 02 92680

  • CAS :

    846023-24-3

  • Molecular Formula : C10H8Cl2N2O2

  • Molecular Weight : 259.09

stdClass Object
(
    [pname] => Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate
    [catalogue_number] => PA 02 0921000
    [category_ids] => ,80,79,78,70,82,84,
    [chemical_name] => 
    [weight] => 273.71
    [form] => C12H16ClNO4
    [cas] => 214470-59-4
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PA 02 0921000

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate


  • Catalogue No.:PA 02 0921000

  • CAS :

    214470-59-4

  • Molecular Formula : C12H16ClNO4

  • Molecular Weight : 273.71

stdClass Object
(
    [pname] => 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile
    [catalogue_number] => PA 02 0921030
    [category_ids] => ,70,71,78,80,81,82,162,
    [chemical_name] => 
    [weight] => 545.42
    [form] => C25H26Cl2N6O4
    [cas] => NA
    [pslug] => 4-2-4-dichloro-5-methoxyphenyl-amino-6-methoxy-7-3-4-nitrosopiperazin-1-yl-propoxy-quinoline-3-carbonitrile-pa020921030
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PA 02 0921030

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile


  • Catalogue No.:PA 02 0921030

  • CAS :

    NA

  • Molecular Formula : C25H26Cl2N6O4

  • Molecular Weight : 545.42

stdClass Object
(
    [pname] => Bosutinib Oxydechlorinated Impurity
    [catalogue_number] => PA 02 0921031
    [category_ids] => ,80,71,81,78,82,
    [chemical_name] => 
    [weight] => 512.01
    [form] => C26H30ClN5O4
    [cas] => NA
    [pslug] => bosutinib-oxydechlorinated-impurity-pa020921031
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PA 02 0921031

Bosutinib Oxydechlorinated Impurity


  • Catalogue No.:PA 02 0921031

  • CAS :

    NA

  • Molecular Formula : C26H30ClN5O4

  • Molecular Weight : 512.01