Darunavir-impurities | Pharmaffiliates

darunavir

A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Darunavir - API Standards 
    [catalogue_number] => PA 04 06000
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 206361-99-1
    [pslug] => 206361-99-1-darunavir-api-pa0406000
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PA 04 06000

Darunavir - API Standards


  • Catalogue No.:PA 04 06000

  • CAS :

    206361-99-1

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Ethanolate - API Standards 
    [catalogue_number] => PA 04 06650
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 593.73
    [form] => C29H43N3O8S
    [cas] => 635728-49-3
    [pslug] => 635728-49-3-darunavir-ethanolate-pa0406650
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PA 04 06650

Darunavir Ethanolate - API Standards


  • Catalogue No.:PA 04 06650

  • CAS :

    635728-49-3

  • Molecular Formula : C29H43N3O8S

  • Molecular Weight : 593.73

stdClass Object
(
    [pname] => Darunavir O-β-D-Glucuronide
    [catalogue_number] => PA 04 06520
    [category_ids] => ,79,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 723.79
    [form] => C33H45N3O13S
    [cas] => 1159613-25-8
    [pslug] => 1159613-25-8-darunavir-o-beta-d-glucuronide-pa0406520
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PA 04 06520

Darunavir O-β-D-Glucuronide


  • Catalogue No.:PA 04 06520

  • CAS :

    1159613-25-8

  • Molecular Formula : C33H45N3O13S

  • Molecular Weight : 723.79

stdClass Object
(
    [pname] => (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate
    [catalogue_number] => PA 04 06540
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => NA
    [pslug] => 3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-4-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutylsulfamoyl-phenylcarbamate-pa0406540
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PA 04 06540

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate


  • Catalogue No.:PA 04 06540

  • CAS :

    NA

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Diamino Impurity
    [catalogue_number] => PA 04 06570
    [category_ids] => 88,82,80,79,78,76,75,70
    [chemical_name] => 
    [weight] => 391.53
    [form] => C20H29N3O3S
    [cas] => 169280-56-2
    [pslug] => 169280-56-2-darunavir-diamino-impurity-pa0406570
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PA 04 06570

Darunavir Diamino Impurity


  • Catalogue No.:PA 04 06570

  • CAS :

    169280-56-2

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => Darunavir Urea Impurity
    [catalogue_number] => PA 04 06580
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 2514705-71-4
    [pslug] => 2514705-71-4-darunavir-urea-impurity-pa0406580
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PA 04 06580

Darunavir Urea Impurity


  • Catalogue No.:PA 04 06580

  • CAS :

    2514705-71-4

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => Darunavir Amine Dimer Impurity
    [catalogue_number] => PA 04 06590
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 965.19
    [form] => C48H64N6O11S2
    [cas] => NA
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PA 04 06590

Darunavir Amine Dimer Impurity


  • Catalogue No.:PA 04 06590

  • CAS :

    NA

  • Molecular Formula : C48H64N6O11S2

  • Molecular Weight : 965.19

stdClass Object
(
    [pname] => Darunavir Furan Dimer Impurity
    [catalogue_number] => PA 04 06600
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 703.8
    [form] => C34H45N3O11S
    [cas] => NA
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PA 04 06600

Darunavir Furan Dimer Impurity


  • Catalogue No.:PA 04 06600

  • CAS :

    NA

  • Molecular Formula : C34H45N3O11S

  • Molecular Weight : 703.8

stdClass Object
(
    [pname] => Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    [catalogue_number] => PA 04 06610
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 867.09
    [form] => C43H58N6O9S2
    [cas] => NA
    [pslug] => benzyl-2s-3r-4-4-3-2s-3r-4-4-amino-n-isobutylphenylsulfonamido-3-hydrxy-1-phenylbutan-2-yl-ureido-n-isobutylsulfonamido-3-hydroxy-1-phenylbutan-2-ylcarbamate-pa0406610
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PA 04 06610

Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate


  • Catalogue No.:PA 04 06610

  • CAS :

    NA

  • Molecular Formula : C43H58N6O9S2

  • Molecular Weight : 867.09

stdClass Object
(
    [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06620
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 525.66
    [form] => C28H35N3O5S
    [cas] => 159005-61-5
    [pslug] => 159005-61-5-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenylmethyl-propyl-carbamic-acid-phenylmethyl-ester-pa0406620
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PA 04 06620

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06620

  • CAS :

    159005-61-5

  • Molecular Formula : C28H35N3O5S

  • Molecular Weight : 525.66

stdClass Object
(
    [pname] => ((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06630
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 681.8
    [form] => C35H43N3O9S
    [cas] => NA
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PA 04 06630

((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06630

  • CAS :

    NA

  • Molecular Formula : C35H43N3O9S

  • Molecular Weight : 681.8

stdClass Object
(
    [pname] => (+)-Darunavir
    [catalogue_number] => PA 04 06640
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 1399859-60-9
    [pslug] => 1399859-60-9-darunavir-pa0406640
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PA 04 06640

(+)-Darunavir


  • Catalogue No.:PA 04 06640

  • CAS :

    1399859-60-9

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Carbamic Acid Impurity
    [catalogue_number] => PA 04 06660
    [category_ids] => ,80,71,78,70,82,79,88,
    [chemical_name] => 
    [weight] => 435.54
    [form] => C21H29N3O5S
    [cas] => 1526916-56-2
    [pslug] => 1526916-56-2-darunavir-carbamic-acid-impurity-pa0406660
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PA 04 06660

Darunavir Carbamic Acid Impurity


  • Catalogue No.:PA 04 06660

  • CAS :

    1526916-56-2

  • Molecular Formula : C21H29N3O5S

  • Molecular Weight : 435.54

stdClass Object
(
    [pname] => 4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide
    [catalogue_number] => PA 04 06670
    [category_ids] => 88,82,80,79,71,70,78
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 1418639-27-6
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PA 04 06670

4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide


  • Catalogue No.:PA 04 06670

  • CAS :

    1418639-27-6

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
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    [pname] => 4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06730
    [category_ids] => ,79,80,78,70,82,88,75,
    [chemical_name] => 
    [weight] => 391.53
    [form] => C20H29N3O3S
    [cas] => 192800-79-6
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PA 04 06730

4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06730

  • CAS :

    192800-79-6

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
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    [pname] => 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06740
    [category_ids] => ,79,80,78,70,82,88,75,
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    [weight] => 391.53
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PA 04 06740

4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06740

  • CAS :

    1402142-62-4

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide
    [catalogue_number] => PA STI 005160
    [category_ids] => ,79,80,76,75,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 400.58
    [form] => C20H20D9N3O3S
    [cas] => 1146967-60-3
    [pslug] => 1146967-60-3-4-amino-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutyl-d9-benzenesulfonamide-pasti005160
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PA STI 005160

4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide


  • Catalogue No.:PA STI 005160

  • CAS :

    1146967-60-3

  • Molecular Formula : C20H20D9N3O3S

  • Molecular Weight : 400.58

stdClass Object
(
    [pname] => Darunavir-d9
    [catalogue_number] => PA STI 024400
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 556.72
    [form] => C27H28D9N3O7S
    [cas] => 1133378-37-6
    [pslug] => 1133378-37-6-darunavir-d9-pasti024400
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PA STI 024400

Darunavir-d9


  • Catalogue No.:PA STI 024400

  • CAS :

    1133378-37-6

  • Molecular Formula : C27H28D9N3O7S

  • Molecular Weight : 556.72

stdClass Object
(
    [pname] => 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
    [catalogue_number] => PA 04 06800
    [category_ids] => ,79,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 271.23
    [form] => C11H13NO7
    [cas] => 253265-98-4
    [pslug] => 253265-98-4-2-5-dioxopyrrolidin-1-yl-3s-3ar-6as-hexahydrofuro-2-3-b-furan-3-yl-carbonate-pa0406800
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PA 04 06800

2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate


  • Catalogue No.:PA 04 06800

  • CAS :

    253265-98-4

  • Molecular Formula : C11H13NO7

  • Molecular Weight : 271.23

stdClass Object
(
    [pname] => Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate
    [catalogue_number] => PA 04 0061035
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 599.81
    [form] => C34H53N3O6
    [cas] => 2307745-62-4
    [pslug] => 2307745-62-4-di-tert-butyl-2s-2s-3r-3r-isobutylazanediyl-bis-3-hydroxy-1-phenylbutane-4-2-diyl-dicarbamate-pa040061035
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PA 04 0061035

Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate


  • Catalogue No.:PA 04 0061035

  • CAS :

    2307745-62-4

  • Molecular Formula : C34H53N3O6

  • Molecular Weight : 599.81

stdClass Object
(
    [pname] => Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
    [catalogue_number] => PA 04 0061036
    [category_ids] => ,80,71,81,78,82,
    [chemical_name] => 
    [weight] => 299.8
    [form] => C15H22ClNO3
    [cas] => 165727-45-7
    [pslug] => 165727-45-7-tert-butyl-2s-3s-4-chloro-3-hydroxy-1-phenylbutan-2-yl-carbamate-pa040061036
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PA 04 0061036

Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate


  • Catalogue No.:PA 04 0061036

  • CAS :

    165727-45-7

  • Molecular Formula : C15H22ClNO3

  • Molecular Weight : 299.8