darunavir

Aromatics - A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Darunavir
    [catalogue_number] => PA 04 06000
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 206361-99-1
    [pslug] => 206361-99-1-darunavir-api-pa0406000
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PA 04 06000
PA 04 06000

Darunavir


  • Catalogue No.:PA 04 06000

  • CAS :

    206361-99-1

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir O-β-D-Glucuronide
    [catalogue_number] => PA 04 06520
    [category_ids] => ,79,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 723.79
    [form] => C33H45N3O13S
    [cas] => 1159613-25-8
    [pslug] => 1159613-25-8-darunavir-o-beta-d-glucuronide-pa0406520
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PA 04 06520
PA 04 06520

Darunavir O-β-D-Glucuronide


  • Catalogue No.:PA 04 06520

  • CAS :

    1159613-25-8

  • Molecular Formula : C33H45N3O13S

  • Molecular Weight : 723.79

stdClass Object
(
    [pname] => (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate
    [catalogue_number] => PA 04 06540
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => NA
    [pslug] => 3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-4-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutylsulfamoyl-phenylcarbamate-pa0406540
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PA 04 06540
PA 04 06540

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate


  • Catalogue No.:PA 04 06540

  • CAS :

    NA

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Diamino Impurity
    [catalogue_number] => PA 04 06570
    [category_ids] => ,88,82,80,79,78,76,75,70,
    [chemical_name] => 
    [weight] => 391.53
    [form] => C20H29N3O3S
    [cas] => 169280-56-2
    [pslug] => 169280-56-2-darunavir-diamino-impurity-pa0406570
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PA 04 06570
PA 04 06570

Darunavir Diamino Impurity


  • Catalogue No.:PA 04 06570

  • CAS :

    169280-56-2

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => Darunavir Urea Impurity
    [catalogue_number] => PA 04 06580
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 2514705-71-4
    [pslug] => 2514705-71-4-darunavir-urea-impurity-pa0406580
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PA 04 06580
PA 04 06580

Darunavir Urea Impurity


  • Catalogue No.:PA 04 06580

  • CAS :

    2514705-71-4

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => Darunavir Amine Dimer Impurity
    [catalogue_number] => PA 04 06590
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 965.19
    [form] => C48H64N6O11S2
    [cas] => NA
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PA 04 06590
PA 04 06590

Darunavir Amine Dimer Impurity


  • Catalogue No.:PA 04 06590

  • CAS :

    NA

  • Molecular Formula : C48H64N6O11S2

  • Molecular Weight : 965.19

stdClass Object
(
    [pname] => Darunavir Furan Dimer Impurity
    [catalogue_number] => PA 04 06600
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 703.8
    [form] => C34H45N3O11S
    [cas] => NA
    [pslug] => darunavir-furan-dimer-impurity-pa0406600
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PA 04 06600
PA 04 06600

Darunavir Furan Dimer Impurity


  • Catalogue No.:PA 04 06600

  • CAS :

    NA

  • Molecular Formula : C34H45N3O11S

  • Molecular Weight : 703.8

stdClass Object
(
    [pname] => Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    [catalogue_number] => PA 04 06610
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 867.09
    [form] => C43H58N6O9S2
    [cas] => NA
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PA 04 06610
PA 04 06610

Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate


  • Catalogue No.:PA 04 06610

  • CAS :

    NA

  • Molecular Formula : C43H58N6O9S2

  • Molecular Weight : 867.09

stdClass Object
(
    [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06620
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 525.66
    [form] => C28H35N3O5S
    [cas] => 159005-61-5
    [pslug] => 159005-61-5-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenylmethyl-propyl-carbamic-acid-phenylmethyl-ester-pa0406620
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PA 04 06620
PA 04 06620

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06620

  • CAS :

    159005-61-5

  • Molecular Formula : C28H35N3O5S

  • Molecular Weight : 525.66

stdClass Object
(
    [pname] => ((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06630
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 681.8
    [form] => C35H43N3O9S
    [cas] => NA
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PA 04 06630
PA 04 06630

((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06630

  • CAS :

    NA

  • Molecular Formula : C35H43N3O9S

  • Molecular Weight : 681.8

stdClass Object
(
    [pname] => (+)-Darunavir
    [catalogue_number] => PA 04 06640
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 1399859-60-9
    [pslug] => 1399859-60-9-darunavir-pa0406640
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PA 04 06640
PA 04 06640

(+)-Darunavir


  • Catalogue No.:PA 04 06640

  • CAS :

    1399859-60-9

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Ethanolate
    [catalogue_number] => PA 04 06650
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 593.73
    [form] => C29H43N3O8S
    [cas] => 635728-49-3
    [pslug] => 635728-49-3-darunavir-ethanolate-pa0406650
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PA 04 06650
PA 04 06650

Darunavir Ethanolate


  • Catalogue No.:PA 04 06650

  • CAS :

    635728-49-3

  • Molecular Formula : C29H43N3O8S

  • Molecular Weight : 593.73

stdClass Object
(
    [pname] => Darunavir Carbamic Acid Impurity
    [catalogue_number] => PA 04 06660
    [category_ids] => ,80,71,78,70,82,79,88,
    [chemical_name] => 
    [weight] => 435.54
    [form] => C21H29N3O5S
    [cas] => 1526916-56-2
    [pslug] => 1526916-56-2-darunavir-carbamic-acid-impurity-pa0406660
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PA 04 06660
PA 04 06660

Darunavir Carbamic Acid Impurity


  • Catalogue No.:PA 04 06660

  • CAS :

    1526916-56-2

  • Molecular Formula : C21H29N3O5S

  • Molecular Weight : 435.54

stdClass Object
(
    [pname] => 4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide
    [catalogue_number] => PA 04 06670
    [category_ids] => ,88,82,80,79,71,70,78,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 1418639-27-6
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PA 04 06670
PA 04 06670

4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide


  • Catalogue No.:PA 04 06670

  • CAS :

    1418639-27-6

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => 4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06730
    [category_ids] => ,79,80,78,70,82,88,75,
    [chemical_name] => 
    [weight] => 391.53
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PA 04 06730
PA 04 06730

4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06730

  • CAS :

    192800-79-6

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06740
    [category_ids] => ,79,80,78,70,82,88,75,
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    [weight] => 391.53
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PA 04 06740
PA 04 06740

4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06740

  • CAS :

    1402142-62-4

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide
    [catalogue_number] => PA STI 005160
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    [chemical_name] => 
    [weight] => 400.58
    [form] => C20H20D9N3O3S
    [cas] => 1146967-60-3
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PA STI 005160
PA STI 005160

4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide


  • Catalogue No.:PA STI 005160

  • CAS :

    1146967-60-3

  • Molecular Formula : C20H20D9N3O3S

  • Molecular Weight : 400.58

stdClass Object
(
    [pname] => Darunavir-d9
    [catalogue_number] => PA STI 024400
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 556.72
    [form] => C27H28D9N3O7S
    [cas] => 1133378-37-6
    [pslug] => 1133378-37-6-darunavir-d9-pasti024400
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PA STI 024400
PA STI 024400

Darunavir-d9


  • Catalogue No.:PA STI 024400

  • CAS :

    1133378-37-6

  • Molecular Formula : C27H28D9N3O7S

  • Molecular Weight : 556.72

stdClass Object
(
    [pname] => Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate
    [catalogue_number] => PA 04 0061035
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    [weight] => 599.81
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PA 04 0061035
PA 04 0061035

Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate


  • Catalogue No.:PA 04 0061035

  • CAS :

    2307745-62-4

  • Molecular Formula : C34H53N3O6

  • Molecular Weight : 599.81

stdClass Object
(
    [pname] => Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
    [catalogue_number] => PA 04 0061036
    [category_ids] => ,80,71,81,78,82,
    [chemical_name] => 
    [weight] => 299.8
    [form] => C15H22ClNO3
    [cas] => 165727-45-7
    [pslug] => 165727-45-7-tert-butyl-2s-3s-4-chloro-3-hydroxy-1-phenylbutan-2-yl-carbamate-pa040061036
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PA 04 0061036
PA 04 0061036

Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate


  • Catalogue No.:PA 04 0061036

  • CAS :

    165727-45-7

  • Molecular Formula : C15H22ClNO3

  • Molecular Weight : 299.8

stdClass Object
(
    [pname] => N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-(methylamino)benzenesulfonamide
    [catalogue_number] => PA 04 0061037
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 405.56
    [form] => C21H31N3O3S
    [cas] => 2765293-23-8
    [pslug] => 2765293-23-8-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutyl-4-methylamino-benzenesulfonamide-pa040061037
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PA 04 0061037
PA 04 0061037

N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-(methylamino)benzenesulfonamide


  • Catalogue No.:PA 04 0061037

  • CAS :

    2765293-23-8

  • Molecular Formula : C21H31N3O3S

  • Molecular Weight : 405.56

stdClass Object
(
    [pname] => (2R,3S)-3-Amino-1-(isobutylamino)-4-phenylbutan-2-ol Hydrochloride
    [catalogue_number] => PA 04 0061038
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 272.82
    [form] => C14H25ClN2O
    [cas] => NA
    [pslug] => 2r-3s-3-amino-1-isobutylamino-4-phenylbutan-2-ol-hydrochloride-pa040061038
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PA 04 0061038
PA 04 0061038

(2R,3S)-3-Amino-1-(isobutylamino)-4-phenylbutan-2-ol Hydrochloride


  • Catalogue No.:PA 04 0061038

  • CAS :

    NA

  • Molecular Formula : C14H25ClN2O

  • Molecular Weight : 272.82

stdClass Object
(
    [pname] => N1-((2R,3S)-4-((4-Amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-N4-((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)succinamide
    [catalogue_number] => PA 04 0061039
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 865.12
    [form] => C44H60N6O8S2
    [cas] => NA
    [pslug] => n1-2r-3s-4-4-amino-n-isobutylphenyl-sulfonamido-3-hydroxy-1-phenylbutan-2-yl-n4-2s-3r-4-4-amino-n-isobutylphenyl-sulfonamido-3-hydroxy-1-phenylbutan-2-yl-succinamide-pa040061039
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PA 04 0061039
PA 04 0061039

N1-((2R,3S)-4-((4-Amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-N4-((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)succinamide


  • Catalogue No.:PA 04 0061039

  • CAS :

    NA

  • Molecular Formula : C44H60N6O8S2

  • Molecular Weight : 865.12

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