donepezil

Aromatics - A reversible acetylcholinesterase inhibitor, Donepezil is used for the treatment of of Alzheimer's disease. It is a medication used in palliative treatment. It works by inhibiting the hydrolysis of acetylcholine.. Reference standards of Donepezil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Donepezil - Impurity B
    [catalogue_number] => PA 04 40020
    [category_ids] => ,80,70,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 2107-69-9
    [pslug] => 2107-69-9-donepezil-impurity-b-pa0440020
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PA 04 40020
PA 04 40020

Donepezil - Impurity B


  • Catalogue No.:PA 04 40020

  • CAS :

    2107-69-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => Deoxy Donepezil Hydrochloride
    [catalogue_number] => PA 04 40560
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 401.97
    [form] => C24H32ClNO2
    [cas] => 1034439-57-0
    [pslug] => 1034439-57-0-deoxy-donepezil-hydrochloride-pa0440560
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PA 04 40560
PA 04 40560

Deoxy Donepezil Hydrochloride


  • Catalogue No.:PA 04 40560

  • CAS :

    1034439-57-0

  • Molecular Formula : C24H32ClNO2

  • Molecular Weight : 401.97

stdClass Object
(
    [pname] => Donepezil Pyridine N-Oxide
    [catalogue_number] => PA 04 40620
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 299.32
    [form] => C17H17NO4
    [cas] => 896134-07-9
    [pslug] => 896134-07-9-donepezil-pyridine-n-oxide-pa0440620
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PA 04 40620
PA 04 40620

Donepezil Pyridine N-Oxide


  • Catalogue No.:PA 04 40620

  • CAS :

    896134-07-9

  • Molecular Formula : C17H17NO4

  • Molecular Weight : 299.32

stdClass Object
(
    [pname] => 4,5-Dimethoxy-1-indanone
    [catalogue_number] => PA 04 40630
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 6342-80-9
    [pslug] => 6342-80-9-4-5-dimethoxy-1-indanone-pa0440630
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PA 04 40630
PA 04 40630

4,5-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40630

  • CAS :

    6342-80-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 4,6-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40640
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 13336-32-8
    [pslug] => 13336-32-8-4-6-dimethoxy-2-3-dihydroinden-1-one-pa0440640
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PA 04 40640
PA 04 40640

4,6-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40640

  • CAS :

    13336-32-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
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    [pname] => 4,7-Dimethoxy-1-indanone
    [catalogue_number] => PA 04 40650
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    [weight] => 192.21
    [form] => C11H12O3
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PA 04 40650
PA 04 40650

4,7-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40650

  • CAS :

    52428-09-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
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    [pname] => 5,7-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40660
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    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 880-87-5
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PA 04 40660
PA 04 40660

5,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40660

  • CAS :

    880-87-5

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
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    [pname] => 6,7-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40670
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    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 57441-74-4
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PA 04 40670
PA 04 40670

6,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40670

  • CAS :

    57441-74-4

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
    [catalogue_number] => PA 04 40680
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 379.49
    [form] => C24H29NO3
    [cas] => 736104-42-0
    [pslug] => 736104-42-0-1-benzyl-4-6-7-dimethoxy-1-oxoindan-2-yl-methyl-piperidine-pa0440680
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PA 04 40680
PA 04 40680

1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine


  • Catalogue No.:PA 04 40680

  • CAS :

    736104-42-0

  • Molecular Formula : C24H29NO3

  • Molecular Weight : 379.49

stdClass Object
(
    [pname] => Donepezil Dehydro Impurity (E/Z mixture)
    [catalogue_number] => PA 04 40690
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 377.48
    [form] => C24H27NO3
    [cas] => 120014-07-5
    [pslug] => 120014-07-5-donepezil-dehydro-impurity-e-z-mixture-pa0440690
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PA 04 40690
PA 04 40690

Donepezil Dehydro Impurity (E/Z mixture)


  • Catalogue No.:PA 04 40690

  • CAS :

    120014-07-5

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

stdClass Object
(
    [pname] => Donepezil Hydrochloride Monohydrate - Impurity G
    [catalogue_number] => PA 04 40700
    [category_ids] => ,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 377.48
    [form] => C24H27NO3
    [cas] => 2452407-72-4
    [pslug] => 2452407-72-4-donepezil-hydrochloride-monohydrate-impurity-g-pa0440700
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PA 04 40700
PA 04 40700

Donepezil Hydrochloride Monohydrate - Impurity G


  • Catalogue No.:PA 04 40700

  • CAS :

    2452407-72-4

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

stdClass Object
(
    [pname] => 5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one
    [catalogue_number] => PA 04 40720
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 287.35
    [form] => C17H21NO3
    [cas] => 149874-91-9
    [pslug] => 149874-91-9-5-6-dimethoxy-2-4-piperidinyl-methyleneindan-1-one-pa0440720
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PA 04 40720
PA 04 40720

5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one


  • Catalogue No.:PA 04 40720

  • CAS :

    149874-91-9

  • Molecular Formula : C17H21NO3

  • Molecular Weight : 287.35

stdClass Object
(
    [pname] => 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3
    [catalogue_number] => PA STI 011340
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 380.45
    [form] => C2113C3H27NO3
    [cas] => 1185239-87-5
    [pslug] => 1185239-87-5-1-benzyl-4-5-6-dimethoxy-1-oxoindan-2-ylidene-methyl-piperidine-13c3-pasti011340
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PA STI 011340
PA STI 011340

1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3


  • Catalogue No.:PA STI 011340

  • CAS :

    1185239-87-5

  • Molecular Formula : C2113C3H27NO3

  • Molecular Weight : 380.45

stdClass Object
(
    [pname] => 4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide
    [catalogue_number] => PA STI 032760
    [category_ids] => ,70,71,78,80,81,82,98,
    [chemical_name] => 
    [weight] => 564.61
    [form] => C31H22D14BrNO3
    [cas] => NA
    [pslug] => 4-2-3-dihydro-5-6-dimethoxy-1-oxo-1h-inden-2-yl-methyl-1-1-bis-phenylmethyl-piperidinium-d14-bromide-pasti032760
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PA STI 032760
PA STI 032760

4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide


  • Catalogue No.:PA STI 032760

  • CAS :

    NA

  • Molecular Formula : C31H22D14BrNO3

  • Molecular Weight : 564.61

stdClass Object
(
    [pname] => 5,6-Dimethoxy-1-indanone-13C3
    [catalogue_number] => PA STI 033470
    [category_ids] => ,80,70,98,
    [chemical_name] => 
    [weight] => 195.19
    [form] => C813C3H12O3
    [cas] => 1185155-55-8
    [pslug] => 1185155-55-8-5-6-dimethoxy-1-indanone-13c3-pasti033470
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PA STI 033470
PA STI 033470

5,6-Dimethoxy-1-indanone-13C3


  • Catalogue No.:PA STI 033470

  • CAS :

    1185155-55-8

  • Molecular Formula : C813C3H12O3

  • Molecular Weight : 195.19

stdClass Object
(
    [pname] => Donepezil-d7 Hydrochloride
    [catalogue_number] => PA STI 036190
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 423.00
    [form] => C24H23D7ClNO3
    [cas] =>   1261394-20-0
    [pslug] => 1261394-20-0-donepezil-d7-hydrochloride-pasti036190
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PA STI 036190
PA STI 036190

Donepezil-d7 Hydrochloride


  • Catalogue No.:PA STI 036190

  • CAS :

    1261394-20-0

  • Molecular Formula : C24H23D7ClNO3

  • Molecular Weight : 423.00

stdClass Object
(
    [pname] => Donepezil-13C3 Hydrochloride
    [catalogue_number] => PA STI 036200
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 418.93
    [form] => C2113C3H30ClNO3
    [cas] => 1246814-90-3
    [pslug] => 1246814-90-3-donepezil-13c3-hydrochloride-pasti036200
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PA STI 036200
PA STI 036200

Donepezil-13C3 Hydrochloride


  • Catalogue No.:PA STI 036200

  • CAS :

    1246814-90-3

  • Molecular Formula : C2113C3H30ClNO3

  • Molecular Weight : 418.93

stdClass Object
(
    [pname] => Donepezil - Impurity E (Bromide Salt)
    [catalogue_number] => PA 04 40050
    [category_ids] => ,70,71,75,78,80,82,
    [chemical_name] => 
    [weight] => 454.36
    [form] => C24H24BrNO3
    [cas] => 231283-82-2
    [pslug] => 231283-82-2-donepezil-impurity-e-bromide-salt-pa0440050
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PA 04 40050
PA 04 40050

Donepezil - Impurity E (Bromide Salt)


  • Catalogue No.:PA 04 40050

  • CAS :

    231283-82-2

  • Molecular Formula : C24H24BrNO3

  • Molecular Weight : 454.36

stdClass Object
(
    [pname] => 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
    [catalogue_number] => PA 04 40740
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 281.31
    [form] => C17H15NO3
    [cas] => 4803-74-1
    [pslug] => 4803-74-1-5-6-dimethoxy-2-4-pyridylmethylene-1-indanone-pa0440740
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PA 04 40740
PA 04 40740

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone


  • Catalogue No.:PA 04 40740

  • CAS :

    4803-74-1

  • Molecular Formula : C17H15NO3

  • Molecular Weight : 281.31

stdClass Object
(
    [pname] => 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one
    [catalogue_number] => PA 04 40750
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 297.31
    [form] => C17H15NO4
    [cas] => 896134-06-8
    [pslug] => 896134-06-8-2-3-dihydro-5-6-dimethoxy-2-1-oxido-4-pyridinyl-methylene-1h-inden-1-one-pa0440750
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PA 04 40750
PA 04 40750

2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one


  • Catalogue No.:PA 04 40750

  • CAS :

    896134-06-8

  • Molecular Formula : C17H15NO4

  • Molecular Weight : 297.31

stdClass Object
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    [catalogue_number] => PA 04 40760
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    [chemical_name] => 
    [weight] => 399.96
    [form] => C24H30ClNO2
    [cas] => 130927-68-3
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PA 04 40760
PA 04 40760

Dehydrodeoxy Donepezil Hydrochloride


  • Catalogue No.:PA 04 40760

  • CAS :

    130927-68-3

  • Molecular Formula : C24H30ClNO2

  • Molecular Weight : 399.96

stdClass Object
(
    [pname] => Donepezil Keto Acid Sodium Salt
    [catalogue_number] => PA 04 40770
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 433.48
    [form] => C24H28NNaO5
    [cas] => NA
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PA 04 40770
PA 04 40770

Donepezil Keto Acid Sodium Salt


  • Catalogue No.:PA 04 40770

  • CAS :

    NA

  • Molecular Formula : C24H28NNaO5

  • Molecular Weight : 433.48

stdClass Object
(
    [pname] => Donepezil Open-Ring Hydroxy Acid
    [catalogue_number] => PA 04 40780
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 413.51
    [form] => C24H31NO5
    [cas] => NA
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PA 04 40780
PA 04 40780

Donepezil Open-Ring Hydroxy Acid


  • Catalogue No.:PA 04 40780

  • CAS :

    NA

  • Molecular Formula : C24H31NO5

  • Molecular Weight : 413.51

stdClass Object
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    [pname] => 2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
    [catalogue_number] => PA 04 40790
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => NA
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PA 04 40790
PA 04 40790

2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40790

  • CAS :

    NA

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

stdClass Object
(
    [pname] => 2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
    [catalogue_number] => PA 04 40800
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => 2514735-34-1
    [pslug] => 2514735-34-1-2-1-benzyl-3-hydroxypiperidin-4-yl-methyl-5-6-dimethoxy-2-3-dihydro-1h-inden-1-one-pa0440800
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PA 04 40800
PA 04 40800

2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40800

  • CAS :

    2514735-34-1

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

stdClass Object
(
    [pname] => Donepezil Hydrochloride Monohydrate - Impurity C
    [catalogue_number] => PA 04 40030
    [category_ids] => ,70,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => 2452407-76-8
    [pslug] => 2452407-76-8-donepezil-hydrochloride-monohydrate-impurity-c-pa0440030
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PA 04 40030
PA 04 40030

Donepezil Hydrochloride Monohydrate - Impurity C


  • Catalogue No.:PA 04 40030

  • CAS :

    2452407-76-8

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

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