Ivacaftor-impurities | Pharmaffiliates

ivacaftor

Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ivacaftor - API Standards 
    [catalogue_number] => PA 09 40000
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 392.49
    [form] => C24H28N2O3
    [cas] => 873054-44-5
    [pslug] => 873054-44-5-ivacaftor-api-pa0940000
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PA 09 40000

Ivacaftor - API Standards


  • Catalogue No.:PA 09 40000

  • CAS :

    873054-44-5

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.49

20% OFF
stdClass Object
(
    [pname] => 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid
    [catalogue_number] => PA 09 40510
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 189.17
    [form] => C10H7NO3
    [cas] => 13721-01-2
    [pslug] => 13721-01-2-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa0940510
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    [offers_product_code] => PA 09 40510
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PA 09 40510

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid


  • Catalogue No.:PA 09 40510

  • CAS :

    13721-01-2

  • Molecular Formula : C10H7NO3

  • Molecular Weight : 189.17

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stdClass Object
(
    [pname] => 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
    [catalogue_number] => PA 09 40520
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 217.22
    [form] => C12H11NO3
    [cas] => 52980-28-6
    [pslug] => 52980-28-6-1-4-dihydro-4-oxo-3-quinolinecarboxylic-acid-ethyl-ester-pa0940520
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    [offers_product_id] => 2413
    [offers_product_code] => PA 09 40520
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PA 09 40520

1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester


  • Catalogue No.:PA 09 40520

  • CAS :

    52980-28-6

  • Molecular Formula : C12H11NO3

  • Molecular Weight : 217.22

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stdClass Object
(
    [pname] => 5-Amino-2,4-di-tert-butylphenol
    [catalogue_number] => PA 09 40530
    [category_ids] => ,80,
    [chemical_name] => 
    [weight] => 221.34
    [form] => C14H23NO
    [cas] => 873055-58-4
    [pslug] => 873055-58-4-5-amino-2-4-di-tert-butylphenol-pa0940530
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    [offers_product_id] => 2414
    [offers_product_code] => PA 09 40530
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PA 09 40530

5-Amino-2,4-di-tert-butylphenol


  • Catalogue No.:PA 09 40530

  • CAS :

    873055-58-4

  • Molecular Formula : C14H23NO

  • Molecular Weight : 221.34

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stdClass Object
(
    [pname] => 2,4-Di-tert-butyl-6-nitrophenol
    [catalogue_number] => PA 09 0401003
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 251.33
    [form] => C14H21NO3
    [cas] => 20039-94-5
    [pslug] => 20039-94-5-2-4-di-tert-butyl-6-nitrophenol-pa090401003
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    [offers_product_code] => PA 09 0401003
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PA 09 0401003

2,4-Di-tert-butyl-6-nitrophenol


  • Catalogue No.:PA 09 0401003

  • CAS :

    20039-94-5

  • Molecular Formula : C14H21NO3

  • Molecular Weight : 251.33

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stdClass Object
(
    [pname] => 5-Amino-2,4-di-tert-butylphenyl methyl carbonate
    [catalogue_number] => PA 09 0401009
    [category_ids] => ,80,78,82,
    [chemical_name] => 
    [weight] => 279.38
    [form] => C16H25NO3
    [cas] => 1182822-31-6
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PA 09 0401009

5-Amino-2,4-di-tert-butylphenyl methyl carbonate


  • Catalogue No.:PA 09 0401009

  • CAS :

    1182822-31-6

  • Molecular Formula : C16H25NO3

  • Molecular Weight : 279.38

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stdClass Object
(
    [pname] => Ivacaftor N-glucuronide
    [catalogue_number] => PA 09 40550
    [category_ids] => ,71,75,79,80,95,
    [chemical_name] => 
    [weight] => 568.61
    [form] => C30H36N2O9
    [cas] => NA
    [pslug] => ivacaftor-n-glucuronide-pa0940550
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PA 09 40550

Ivacaftor N-glucuronide


  • Catalogue No.:PA 09 40550

  • CAS :

    NA

  • Molecular Formula : C30H36N2O9

  • Molecular Weight : 568.61

stdClass Object
(
    [pname] => Ivacaftor Carboxylic Acid
    [catalogue_number] => PA 09 40560
    [category_ids] => ,80,79,71,75,
    [chemical_name] => 
    [weight] => 422.47
    [form] => C24H26N2O5
    [cas] => 1246213-24-0
    [pslug] => 1246213-24-0-ivacaftor-carboxylic-acid-pa0940560
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PA 09 40560

Ivacaftor Carboxylic Acid


  • Catalogue No.:PA 09 40560

  • CAS :

    1246213-24-0

  • Molecular Formula : C24H26N2O5

  • Molecular Weight : 422.47

stdClass Object
(
    [pname] => Hydroxymethyl Ivacaftor
    [catalogue_number] => PA 09 40570
    [category_ids] => ,80,79,71,75,
    [chemical_name] => 
    [weight] => 408.49
    [form] => C24H28N2O4
    [cas] => 1246213-23-9
    [pslug] => 1246213-23-9-hydroxymethyl-ivacaftor-pa0940570
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PA 09 40570

Hydroxymethyl Ivacaftor


  • Catalogue No.:PA 09 40570

  • CAS :

    1246213-23-9

  • Molecular Formula : C24H28N2O4

  • Molecular Weight : 408.49

stdClass Object
(
    [pname] => 4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid
    [catalogue_number] => PA 09 0401004
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 492.57
    [form] => C28H32N2O6
    [cas] => NA
    [pslug] => 4-3-2-4-di-tert-butyl-5-hydroxyphenyl-carbamoyl-4-oxoquinolin-1-4h-yl-4-oxobutanoic-acid-pa090401004
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PA 09 0401004

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid


  • Catalogue No.:PA 09 0401004

  • CAS :

    NA

  • Molecular Formula : C28H32N2O6

  • Molecular Weight : 492.57

stdClass Object
(
    [pname] => 1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
    [catalogue_number] => PA 09 0401005
    [category_ids] => ,70,78,80,82,162,
    [chemical_name] => 
    [weight] => 218.17
    [form] => C10H6N2O4
    [cas] => NA
    [pslug] => 1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa090401005
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PA 09 0401005

1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid


  • Catalogue No.:PA 09 0401005

  • CAS :

    NA

  • Molecular Formula : C10H6N2O4

  • Molecular Weight : 218.17

stdClass Object
(
    [pname] => 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
    [catalogue_number] => PA 09 0401006
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 563.65
    [form] => C34H33N3O5
    [cas] => 2760759-55-3
    [pslug] => 2760759-55-3-2-4-di-tert-butyl-5-4-oxo-1-4-dihydroquinoline-3-carboxamido-phenyl-4-oxo-1-4-dihydroquinoline-3-carboxylate-pa090401006
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PA 09 0401006

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate


  • Catalogue No.:PA 09 0401006

  • CAS :

    2760759-55-3

  • Molecular Formula : C34H33N3O5

  • Molecular Weight : 563.65

stdClass Object
(
    [pname] => N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide
    [catalogue_number] => PA 09 0401007
    [category_ids] => ,70,78,80,82,162,
    [chemical_name] => 
    [weight] => 365.39
    [form] => C20H19N3O4
    [cas] => NA
    [pslug] => n-4-tert-butyl-3-hydroxyphenyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401007
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PA 09 0401007

N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide


  • Catalogue No.:PA 09 0401007

  • CAS :

    NA

  • Molecular Formula : C20H19N3O4

  • Molecular Weight : 365.39

stdClass Object
(
    [pname] => Ivacaftor Nitroso Impurity
    [catalogue_number] => PA 09 0401008
    [category_ids] => ,70,78,80,82,162,
    [chemical_name] => 
    [weight] => 421.5
    [form] => C24H27N3O4
    [cas] => NA
    [pslug] => ivacaftor-nitroso-impurity-pa090401008
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PA 09 0401008

Ivacaftor Nitroso Impurity


  • Catalogue No.:PA 09 0401008

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

stdClass Object
(
    [pname] => N-Nitroso Ivacaftor Ortho Isomer
    [catalogue_number] => PA 09 0401010
    [category_ids] => ,70,78,80,82,162,
    [chemical_name] => 
    [weight] => 421.5
    [form] => C24H27N3O4
    [cas] => NA
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PA 09 0401010

N-Nitroso Ivacaftor Ortho Isomer


  • Catalogue No.:PA 09 0401010

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

stdClass Object
(
    [pname] => Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate
    [catalogue_number] => PA 09 0401011
    [category_ids] => ,70,78,80,82,162,
    [chemical_name] => 
    [weight] => 246.22
    [form] => C12H10N2O4
    [cas] => NA
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PA 09 0401011

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate


  • Catalogue No.:PA 09 0401011

  • CAS :

    NA

  • Molecular Formula : C12H10N2O4

  • Molecular Weight : 246.22

stdClass Object
(
    [pname] => 2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate
    [catalogue_number] => PA 09 0401012
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 309.36
    [form] => C16H23NO5
    [cas] => 873055-56-2
    [pslug] => 873055-56-2-2-4-di-tert-butyl-6-nitrophenyl-methyl-carbonate-pa090401012
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PA 09 0401012

2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate


  • Catalogue No.:PA 09 0401012

  • CAS :

    873055-56-2

  • Molecular Formula : C16H23NO5

  • Molecular Weight : 309.36