nintedanib
Aromatics
- A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => (3Z,3'Z)-Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(2-oxoindoline-6-carboxylate)
[catalogue_number] => PA 14 54580
[category_ids] => ,80,75,70,78,82,79,71,
[chemical_name] =>
[weight] => 965.06
[form] => C56H52N8O8
[cas] => 2410284-90-9
[pslug] => 2410284-90-9-3z-3z-dimethyl-3-3-2-2-piperazine-1-4-diyl-bis-acetyl-bis-methylazanediyl-bis-4-1-phenylene-bis-azanediyl-bis-phenylmethanylylidene-bis-2-oxoindoline-6-carboxylate-pa1454580
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(3Z,3'Z)-Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(2-oxoindoline-6-carboxylate)
Catalogue No.:PA 14 54580
Molecular Formula : C56H52N8O8
Molecular Weight : 965.06
stdClass Object
(
[pname] => Methyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 0541086
[category_ids] => ,71,78,80,88,89,162,
[chemical_name] =>
[weight] => 610.67
[form] => C33H34N6O6
[cas] => NA
[pslug] => methyl-z-1-acetyl-3-4-n-methyl-2-4-methylpiperazin-1-yl-acetamido-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541086
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Methyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541086
Molecular Formula : C33H34N6O6
Molecular Weight : 610.67
stdClass Object
(
[pname] => (Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid
[catalogue_number] => PA 14 0541087
[category_ids] => ,71,78,80,88,89,162,
[chemical_name] =>
[weight] => 554.61
[form] => C30H30N6O5
[cas] => NA
[pslug] => z-3-4-n-methyl-2-4-methylpiperazin-1-yl-acetamido-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-6-carboxylic-acid-pa140541087
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(Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid
Catalogue No.:PA 14 0541087
Molecular Formula : C30H30N6O5
Molecular Weight : 554.61
stdClass Object
(
[pname] => Methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 0541088
[category_ids] => ,71,78,80,88,89,162,
[chemical_name] =>
[weight] => 554.61
[form] => C30H30N6O5
[cas] => NA
[pslug] => methyl-z-3-4-2-4-methylpiperazin-1-yl-acetamido-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541088
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Methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541088
Molecular Formula : C30H30N6O5
Molecular Weight : 554.61
stdClass Object
(
[pname] => Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
[catalogue_number] => PA 14 0541089
[category_ids] => ,71,78,80,88,89,162,
[chemical_name] =>
[weight] => 568.63
[form] => C31H32N6O5
[cas] => NA
[pslug] => methyl-z-3-4-n-methyl-2-4-methylpiperazin-1-yl-acetamido-phenyl-nitroso-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541089
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Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541089
Molecular Formula : C31H32N6O5
Molecular Weight : 568.63
