Bortezomib-impurities | Pharmaffiliates

bortezomib

Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.. Reference standards of Bortezomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
    [catalogue_number] => PA 02 79560
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 340.42
    [form] => C19H24N4O2
    [cas] => 1446194-56-4
    [pslug] => 1446194-56-4-n-1s-2-3-methylbutyl-amino-2-oxo-1-phenylmethyl-ethyl-2-pyrazinecarboxamide-pa0279560
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79560

N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide


  • Catalogue No.:PA 02 79560

  • CAS :

    1446194-56-4

  • Molecular Formula : C19H24N4O2

  • Molecular Weight : 340.42

stdClass Object
(
    [pname] => N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 79580
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 340.42
    [form] => C19H24N4O2
    [cas] => NA
    [pslug] => n-1-isopentylamino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa0279580
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79580

N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 79580

  • CAS :

    NA

  • Molecular Formula : C19H24N4O2

  • Molecular Weight : 340.42

stdClass Object
(
    [pname] => (4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
    [catalogue_number] => PA 02 79590
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 386.21
    [form] => C18H23BN4O5
    [cas] => NA
    [pslug] => 4-hydroxy-1-s-3-phenyl-2-pyrazine-2-carboxamido-propanamido-butyl-boronic-acid-pa0279590
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79590

(4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid


  • Catalogue No.:PA 02 79590

  • CAS :

    NA

  • Molecular Formula : C18H23BN4O5

  • Molecular Weight : 386.21

stdClass Object
(
    [pname] => N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 79600
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 504.43
    [form] => C28H37BN4O4
    [cas] => NA
    [pslug] => n-1-1-3a-5-dimethylhexahydro-4-6-methanobenzo-d-1-3-2-dioxaborol-2-yl-3-methylbutyl-amino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa0279600
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79600

N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 79600

  • CAS :

    NA

  • Molecular Formula : C28H37BN4O4

  • Molecular Weight : 504.43

stdClass Object
(
    [pname] => (R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
    [catalogue_number] => PA 02 79610
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 285.3
    [form] => C15H15N3O3
    [cas] => NA
    [pslug] => r-2-n-methylpyrazine-2-carboxamido-3-phenylpropanoic-acid-pa0279610
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79610

(R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid


  • Catalogue No.:PA 02 79610

  • CAS :

    NA

  • Molecular Formula : C15H15N3O3

  • Molecular Weight : 285.3

stdClass Object
(
    [pname] => Bortezomib ((1R,2S)-Bortezomib)
    [catalogue_number] => PA 02 79690
    [category_ids] => ,90,69,70,
    [chemical_name] => 
    [weight] => 1098.67
    [form] => C57H69B3N12O9
    [cas] => 390800-88-1
    [pslug] => 390800-88-1-bortezomib-1r-2s-bortezomib-pa0279690
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79690

Bortezomib ((1R,2S)-Bortezomib)


  • Catalogue No.:PA 02 79690

  • CAS :

    390800-88-1

  • Molecular Formula : C57H69B3N12O9

  • Molecular Weight : 1098.67

stdClass Object
(
    [pname] => (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
    [catalogue_number] => PA 02 79700
    [category_ids] => ,90,69,70,82,78,
    [chemical_name] => 
    [weight] => 518.46
    [form] => C29H39BN4O4
    [cas] => 205393-22-2
    [pslug] => 205393-22-2-1r-1s-2s-3r-5s-pinanediol-n-n-pyrazinylphenylalaninoyl-1-amino-3-methyl-butane-1-boronate-pa0279700
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79700

(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate


  • Catalogue No.:PA 02 79700

  • CAS :

    205393-22-2

  • Molecular Formula : C29H39BN4O4

  • Molecular Weight : 518.46

stdClass Object
(
    [pname] => (R,R)-Hydroxy Des(boric Acid) Bortezomib
    [catalogue_number] => PA 02 79710
    [category_ids] => ,90,69,70,
    [chemical_name] => 
    [weight] => 356.42
    [form] => C19H24N4O3
    [cas] => NA
    [pslug] => r-r-hydroxy-des-boric-acid-bortezomib-pa0279710
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79710

(R,R)-Hydroxy Des(boric Acid) Bortezomib


  • Catalogue No.:PA 02 79710

  • CAS :

    NA

  • Molecular Formula : C19H24N4O3

  • Molecular Weight : 356.42

stdClass Object
(
    [pname] => Bortezomib-D8 (Major)
    [catalogue_number] => PA STI 014210
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 392.29
    [form] => C19H17D8BN4O4
    [cas] => NA
    [pslug] => bortezomib-d8-major-pasti014210
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 014210

Bortezomib-D8 (Major)


  • Catalogue No.:PA STI 014210

  • CAS :

    NA

  • Molecular Formula : C19H17D8BN4O4

  • Molecular Weight : 392.29

stdClass Object
(
    [pname] => (1R,2R)-Bortezomib-d5
    [catalogue_number] => PA STI 014220
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 389.27
    [form] => C19H20D5BN4O4
    [cas] => NA
    [pslug] => 1r-2r-bortezomib-d5-pasti014220
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 014220

(1R,2R)-Bortezomib-d5


  • Catalogue No.:PA STI 014220

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => (1S,2R)-Bortezomib-d5
    [catalogue_number] => PA STI 014230
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 389.27
    [form] => C19H20D5BN4O4
    [cas] => NA
    [pslug] => 1s-2r-bortezomib-d5-pasti014230
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 014230

(1S,2R)-Bortezomib-d5


  • Catalogue No.:PA STI 014230

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => (1S,2S)-Bortezomib-d5
    [catalogue_number] => PA STI 014240
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 389.27
    [form] => C19H20D5BN4O4
    [cas] => NA
    [pslug] => 1s-2s-bortezomib-d5-pasti014240
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 014240

(1S,2S)-Bortezomib-d5


  • Catalogue No.:PA STI 014240

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate-d8
    [catalogue_number] => PA STI 073740
    [category_ids] => ,90,69,70,98,
    [chemical_name] => 
    [weight] => 526.50
    [form] => C29H31D8BN4O4
    [cas] => NA
    [pslug] => 1r-1s-2s-3r-5s-pinanediol-n-n-pyrazinylphenylalaninoyl-1-amino-3-methylbutane-1-boronate-d8-pasti073740
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA STI 073740

(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate-d8


  • Catalogue No.:PA STI 073740

  • CAS :

    NA

  • Molecular Formula : C29H31D8BN4O4

  • Molecular Weight : 526.50

stdClass Object
(
    [pname] => Bortezomib L-Phenylalanyl Analog
    [catalogue_number] => PA 02 79720
    [category_ids] => 76,71,90,69,70,78,82,79,75
    [chemical_name] => 
    [weight] => 531.42
    [form] => C28H34BN5O5
    [cas] => 1194235-41-0
    [pslug] => 1194235-41-0-bortezomib-l-phenylalanyl-analog-pa0279720
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79720

Bortezomib L-Phenylalanyl Analog


  • Catalogue No.:PA 02 79720

  • CAS :

    1194235-41-0

  • Molecular Formula : C28H34BN5O5

  • Molecular Weight : 531.42

stdClass Object
(
    [pname] => (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
    [catalogue_number] => PA 02 79750
    [category_ids] => ,79,90,69,70,
    [chemical_name] => 
    [weight] => 379.23
    [form] => C17H29BF3NO4
    [cas] => 179324-87-9
    [pslug] => 179324-87-9-alpha-r-1s-2s-3r-5s-pinanediol-1-amino-3-methylbutane-1-boronate-trifluoroacetic-acid-salt-pa0279750
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79750

(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt


  • Catalogue No.:PA 02 79750

  • CAS :

    179324-87-9

  • Molecular Formula : C17H29BF3NO4

  • Molecular Weight : 379.23

stdClass Object
(
    [pname] => (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride
    [catalogue_number] => PA 02 79840
    [category_ids] => ,79,90,69,70,82,
    [chemical_name] => 
    [weight] => 434.81
    [form] => C23H36BClN2O3
    [cas] => 205393-21-1
    [pslug] => 205393-21-1-alpha-s-alpha-amino-n-1r-1-3as-4s-6s-7ar-hexahydro-3a-5-5-trimethyl-4-6-methano-1-3-2-benzodioxaborol-2-yl-3-methylbutyl-benzenepropanamide-monohydrochloride-pa0279840
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 79840

(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride


  • Catalogue No.:PA 02 79840

  • CAS :

    205393-21-1

  • Molecular Formula : C23H36BClN2O3

  • Molecular Weight : 434.81

stdClass Object
(
    [pname] => N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 0791038
    [category_ids] => ,90,82,81,78,70,69,
    [chemical_name] => 
    [weight] => 356.43
    [form] => C19H24N4O3
    [cas] => NA
    [pslug] => n-r-1-r-1-hydroxy-3-methylbutyl-amino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa020791038
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 02 0791038

N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 0791038

  • CAS :

    NA

  • Molecular Formula : C19H24N4O3

  • Molecular Weight : 356.43