avanafil

Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer.  Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Avanafil
    [catalogue_number] => PA 28 44000
    [category_ids] => ,80,69,71,78,70,82,92,
    [chemical_name] => 
    [weight] => 483.95
    [form] => C23H26ClN7O3
    [cas] => 330784-47-9
    [pslug] => 330784-47-9-avanafil-api-pa2844000
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PA 28 44000

Avanafil

  • Catalogue No.:PA 28 44000

  • CAS :

    330784-47-9

  • Molecular Formula : C23H26ClN7O3

  • Molecular Weight : 483.95

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Details 
stdClass Object
(
    [pname] => Avanafil-13C5,15N
    [catalogue_number] => PA STI 009310
    [category_ids] => ,80,69,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 489.91
    [form] => C1813C5H26ClN615NO3
    [cas] => 1276495-36-3
    [pslug] => 1276495-36-3-avanafil-13c5-15n-pasti009310
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PA STI 009310

Avanafil-13C5,15N

  • Catalogue No.:PA STI 009310

  • CAS :

    1276495-36-3

  • Molecular Formula : C1813C5H26ClN615NO3

  • Molecular Weight : 489.91

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Details 
stdClass Object
(
    [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid
    [catalogue_number] => PA 28 0441017
    [category_ids] => 92,71,69,70,78,80,82
    [chemical_name] => 
    [weight] => 392.84
    [form] => C18H21ClN4O4
    [cas] => 330785-84-7
    [pslug] => 330785-84-7-s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylic-acid-pa280441017
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PA 28 0441017

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid

  • Catalogue No.:PA 28 0441017

  • CAS :

    330785-84-7

  • Molecular Formula : C18H21ClN4O4

  • Molecular Weight : 392.84

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Details 
stdClass Object
(
    [pname] => 4-(Diethylamino)-4'-sulfoazobenzene
    [catalogue_number] => PA 28 0441018
    [category_ids] => ,80,69,71,78,82,92,
    [chemical_name] => 
    [weight] => 333.41
    [form] => C16H19N3O3S
    [cas] => 6287-12-3
    [pslug] => 6287-12-3-4-diethylamino-4-sulfoazobenzene-pa280441018
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PA 28 0441018

4-(Diethylamino)-4'-sulfoazobenzene

  • Catalogue No.:PA 28 0441018

  • CAS :

    6287-12-3

  • Molecular Formula : C16H19N3O3S

  • Molecular Weight : 333.41

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Details 
stdClass Object
(
    [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
    [catalogue_number] => PA 28 0441019
    [category_ids] => 82,78,71,70,69,162
    [chemical_name] => 
    [weight] => 512.96
    [form] => C23H25ClN8O4
    [cas] => 3050754-67-8
    [pslug] => 3050754-67-8-s-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-n-pyrimidin-2-ylmethyl-pyrimidine-5-carboxamide-pa280441019
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PA 28 0441019

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441019

  • CAS :

    3050754-67-8

  • Molecular Formula : C23H25ClN8O4

  • Molecular Weight : 512.96

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Details 
stdClass Object
(
    [pname] => (1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441020
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 858.78
    [form] => C41H45Cl2N11O6
    [cas] => NA
    [pslug] => 1-4-3-chloro-4-methoxybenzyl-amino-5-pyrimidin-2-ylmethyl-carbamoyl-pyrimidin-2-yl-pyrrolidin-2-yl-methyl-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441020
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PA 28 0441020

(1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441020

  • CAS :

    NA

  • Molecular Formula : C41H45Cl2N11O6

  • Molecular Weight : 858.78

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Details 
stdClass Object
(
    [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxamide
    [catalogue_number] => PA 28 0441021
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 420.85
    [form] => C18H21ClN6O4
    [cas] => NA
    [pslug] => s-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxamide-pa280441021
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PA 28 0441021

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441021

  • CAS :

    NA

  • Molecular Formula : C18H21ClN6O4

  • Molecular Weight : 420.85

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Details 
stdClass Object
(
    [pname] => 4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
    [catalogue_number] => PA 28 0441022
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 459.91
    [form] => C19H18ClN7O3S
    [cas] => NA
    [pslug] => 4-3-chloro-4-methoxybenzyl-nitroso-amino-2-methylthio-n-pyrimidin-2-ylmethyl-pyrimidine-5-carboxamide-pa280441022
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PA 28 0441022

4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441022

  • CAS :

    NA

  • Molecular Formula : C19H18ClN7O3S

  • Molecular Weight : 459.91

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Details 
stdClass Object
(
    [pname] => Ethyl (S)-4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441023
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 449.89
    [form] => C20H24ClN5O5
    [cas] => NA
    [pslug] => ethyl-s-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441023
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PA 28 0441023

Ethyl (S)-4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441023

  • CAS :

    NA

  • Molecular Formula : C20H24ClN5O5

  • Molecular Weight : 449.89

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Details 
stdClass Object
(
    [pname] => ((S)-1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441024
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 887.78
    [form] => C41H44Cl2N12O7
    [cas] => NA
    [pslug] => s-1-4-3-chloro-4-methoxybenzyl-amino-5-pyrimidin-2-ylmethyl-carbamoyl-pyrimidin-2-yl-pyrrolidin-2-yl-methyl-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-s-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441024
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PA 28 0441024

((S)-1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441024

  • CAS :

    NA

  • Molecular Formula : C41H44Cl2N12O7

  • Molecular Weight : 887.78

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Details 
stdClass Object
(
    [pname] => ((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441025
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 887.78
    [form] => C41H44Cl2N12O7
    [cas] => NA
    [pslug] => s-1-4-3-chloro-4-methoxybenzyl-nitroso-amino-5-pyrimidin-2-ylmethyl-carbamoyl-pyrimidin-2-yl-pyrrolidin-2-yl-methyl-4-3-chloro-4-methoxybenzyl-amino-2-s-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441025
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PA 28 0441025

((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441025

  • CAS :

    NA

  • Molecular Formula : C41H44Cl2N12O7

  • Molecular Weight : 887.78

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Details 
stdClass Object
(
    [pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441026
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 396.85
    [form] => C16H17ClN4O4S
    [cas] => NA
    [pslug] => ethyl-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-methylthio-pyrimidine-5-carboxylate-pa280441026
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PA 28 0441026

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441026

  • CAS :

    NA

  • Molecular Formula : C16H17ClN4O4S

  • Molecular Weight : 396.85

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Details 
stdClass Object
(
    [pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
    [catalogue_number] => PA 28 0441027
    [category_ids] => ,69,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 412.85
    [form] => C16H17ClN4O5S
    [cas] => NA
    [pslug] => ethyl-4-3-chloro-4-methoxybenzyl-nitroso-amino-2-methylsulfinyl-pyrimidine-5-carboxylate-pa280441027
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PA 28 0441027

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441027

  • CAS :

    NA

  • Molecular Formula : C16H17ClN4O5S

  • Molecular Weight : 412.85

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CPHI INDIA- 28, 30 November