lopinavir

Chiral standards - Lopinavir is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir. It is an antiretroviral of the protease inhibitor class. Reference standards of Lopinavir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Lopinavir
    [catalogue_number] => PA 12 32000
    [category_ids] => ,77,69,113,78,70,82,
    [chemical_name] => 
    [weight] => 628.80
    [form] => C37H48N4O5
    [cas] => 192725-17-0
    [pslug] => 192725-17-0-lopinavir-api-pa1232000
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Lopinavir

Catalogue No.:PA 12 32000
CAS :
192725-17-0
Molecular Formula : C₃₇H₄₈N₄O₅
Molecular Weight : 628.80

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Details

stdClass Object
(
    [pname] => 4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir
    [catalogue_number] => PA 12 32510
    [category_ids] => ,77,69,113,78,70,82,
    [chemical_name] => 
    [weight] => 626.78
    [form] => C37H46N4O5
    [cas] => NA
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4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir

Catalogue No.:PA 12 32510
CAS :
NA
Molecular Formula : C₃₇H₄₆N₄O₅
Molecular Weight : 626.78

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Details

stdClass Object
(
    [pname] => (S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid-d8
    [catalogue_number] => PA STI 082120
    [category_ids] => ,97,69,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 208.28
    [form] => C9H8D8N2O3
    [cas] => 1323257-58-4
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(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid-d8

Catalogue No.:PA STI 082120
CAS :
1323257-58-4
Molecular Formula : C₉H₈D₈N₂O₃
Molecular Weight : 208.28

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Details

stdClass Object
(
    [pname] => (S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetyl Chloride
    [catalogue_number] => PA STI 082250
    [category_ids] => ,97,69,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 218.68
    [form] => C9H15ClN2O2
    [cas] => 192800-77-4_x0000_
    [pslug] => 192800-77-4-x0000-s-tetrahydro-alpha-1-methylethyl-2-oxo-1-2h-pyrimidineacetyl-chloride-pasti082250
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(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetyl Chloride

Catalogue No.:PA STI 082250
CAS :
192800-77-4_x0000_
Molecular Formula : C₉H₁₅ClN₂O₂
Molecular Weight : 218.68

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Details

stdClass Object
(
    [pname] => Lopinavir - Impurity T
    [catalogue_number] => PA 12 32200
    [category_ids] => ,77,69,75,78,70,82,
    [chemical_name] => 
    [weight] => 919.18
    [form] => C57H66N4O7
    [cas] => 1797024-56-6
    [pslug] => 1797024-56-6-lopinavir-impurity-t-pa1232200
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Lopinavir - Impurity T

Catalogue No.:PA 12 32200
CAS :
1797024-56-6
Molecular Formula : C₅₇H₆₆N₄O₇
Molecular Weight : 919.18

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Details

stdClass Object
(
    [pname] => (2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane
    [catalogue_number] => PA 12 32550
    [category_ids] => ,80,70,69,
    [chemical_name] => 
    [weight] => 384.51
    [form] => C23H32N2O3
    [cas] => 144163-85-9
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(2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane

Catalogue No.:PA 12 32550
CAS :
144163-85-9
Molecular Formula : C₂₃H₃₂N₂O₃
Molecular Weight : 384.51

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Lopinavir - Impurity A

Catalogue No.:PA 12 32010
CAS :
192726-05-9
Molecular Formula : C₂₇H₃₈N₄O₃
Molecular Weight : 466.63

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Details

stdClass Object
(
    [pname] => Lopinavir - Impurity I
    [catalogue_number] => PA 12 32090
    [category_ids] => ,80,69,70,
    [chemical_name] => 
    [weight] => 628.81
    [form] => C37H48N4O5
    [cas] => NA
    [pslug] => lopinavir-impurity-i-pa1232090
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Lopinavir - Impurity I

Catalogue No.:PA 12 32090
CAS :
NA
Molecular Formula : C₃₇H₄₈N₄O₅
Molecular Weight : 628.81

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Details

stdClass Object
(
    [pname] => Lopinavir - Impurity M
    [catalogue_number] => PA 12 32130
    [category_ids] => ,80,69,70,
    [chemical_name] => 
    [weight] => 628.81
    [form] => C37H48N4O5
    [cas] => NA
    [pslug] => lopinavir-impurity-m-pa1232130
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Lopinavir - Impurity M

Catalogue No.:PA 12 32130
CAS :
NA
Molecular Formula : C₃₇H₄₈N₄O₅
Molecular Weight : 628.81

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Details

stdClass Object
(
    [pname] => (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-trifluromethylcarbonylamino-1,6-diphenylhexane
    [catalogue_number] => PA 12 32540
    [category_ids] => ,80,69,70,
    [chemical_name] => 
    [weight] => 542.6
    [form] => C30H33F3N2O4
    [cas] => NA
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(2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-trifluromethylcarbonylamino-1,6-diphenylhexane

Catalogue No.:PA 12 32540
CAS :
NA
Molecular Formula : C₃₀H₃₃F₃N₂O₄
Molecular Weight : 542.6

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Details

stdClass Object
(
    [pname] => Lopinavir - Impurity S
    [catalogue_number] => PA 12 32570
    [category_ids] => ,77,69,75,78,70,82,
    [chemical_name] => 
    [weight] => 790.99
    [form] => C47H58N4O7
    [cas] => 943250-65-5
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Lopinavir - Impurity S

Catalogue No.:PA 12 32570
CAS :
943250-65-5
Molecular Formula : C₄₇H₅₈N₄O₇
Molecular Weight : 790.99

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Details

stdClass Object
(
    [pname] => (R)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic Acid
    [catalogue_number] => PA 12 0321006
    [category_ids] => ,77,69,113,78,70,82,
    [chemical_name] => 
    [weight] => 200.24
    [form] => C9H16N2O3
    [cas] => 1370045-08-1
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(R)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic Acid

Catalogue No.:PA 12 0321006
CAS :
1370045-08-1
Molecular Formula : C₉H₁₆N₂O₃
Molecular Weight : 200.24

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Details

stdClass Object
(
    [pname] => Sulfolopinavir
    [catalogue_number] => PA 12 0321007
    [category_ids] => ,77,69,113,78,70,82,
    [chemical_name] => 
    [weight] => 708.87
    [form] => C37H48N4O8S
    [cas] => NA
    [pslug] => sulfolopinavir-pa120321007
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Sulfolopinavir

Catalogue No.:PA 12 0321007
CAS :
NA
Molecular Formula : C₃₇H₄₈N₄O₈S
Molecular Weight : 708.87

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Details

stdClass Object
(
    [pname] => (S)-N-((2S,4S,5S)-4-Hydroxy-5-(2-(4-(2-(((2S,3S,5S)-3-hydroxy-5-((S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamido)-1,6-diphenylhexan-2-yl)amino)-2-oxoethoxy)-3,5-dimethylphenyl)acetamido)-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
    [catalogue_number] => PA 12 0321009
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 1135.46
    [form] => C66H86N8O9
    [cas] => 1989516-33-7
    [pslug] => 1989516-33-7-s-n-2s-4s-5s-4-hydroxy-5-2-4-2-2s-3s-5s-3-hydroxy-5-s-3-methyl-2-2-oxotetrahydropyrimidin-1-2h-yl-butanamido-1-6-diphenylhexan-2-yl-amino-2-oxoethoxy-3-5-dimethylphenyl-acetamido-1-6-diphenylhexan-2-yl-3-methyl-2-2-oxotetrahydropyrimidin-1-2h-yl-butanamide-pa120321009
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(S)-N-((2S,4S,5S)-4-Hydroxy-5-(2-(4-(2-(((2S,3S,5S)-3-hydroxy-5-((S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamido)-1,6-diphenylhexan-2-yl)amino)-2-oxoethoxy)-3,5-dimethylphenyl)acetamido)-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide

Catalogue No.:PA 12 0321009
CAS :
1989516-33-7
Molecular Formula : C₆₆H₈₆N₈O₉
Molecular Weight : 1135.46

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stdClass Object
(
    [pname] => (S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide
    [catalogue_number] => PA 12 0321010
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 642.84
    [form] => C38H50N4O5
    [cas] => 1132765-60-6
    [pslug] => 1132765-60-6-s-n-2s-4s-5s-5-2-2-6-dimethylphenoxy-acetamido-4-hydroxy-1-6-diphenylhexan-2-yl-4-methyl-2-2-oxotetrahydropyrimidin-1-2h-yl-pentanamide-pa120321010
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(S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide

Catalogue No.:PA 12 0321010
CAS :
1132765-60-6
Molecular Formula : C₃₈H₅₀N₄O₅
Molecular Weight : 642.84

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Details

stdClass Object
(
    [pname] => tert-Butyl ((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate
    [catalogue_number] => PA 12 0321011
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 546.71
    [form] => C33H42N2O5
    [cas] => 192725-45-4
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tert-Butyl ((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Catalogue No.:PA 12 0321011
CAS :
192725-45-4
Molecular Formula : C₃₃H₄₂N₂O₅
Molecular Weight : 546.71

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Details

stdClass Object
(
    [pname] => Abacavir Lopinavir Methylene Conjugation Impurity
    [catalogue_number] => PA 12 0321012
    [category_ids] => ,77,69,78,70,82,
    [chemical_name] => 
    [weight] => 927.16
    [form] => C52H66N10O6
    [cas] => NA
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Abacavir Lopinavir Methylene Conjugation Impurity

Catalogue No.:PA 12 0321012
CAS :
NA
Molecular Formula : C₅₂H₆₆N₁₀O₆
Molecular Weight : 927.16

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Details

stdClass Object
(
    [pname] => rel N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2,2,2-trifluoroacetamide
    [catalogue_number] => PA 12 0321013
    [category_ids] => ,77,69,113,78,70,82,
    [chemical_name] => 
    [weight] => 542.6
    [form] => C30H33F3N2O4
    [cas] => 2125942-48-3
    [pslug] => 2125942-48-3-rel-n-2s-4s-5s-5-2-2-6-dimethylphenoxy-acetamido-4-hydroxy-1-6-diphenylhexan-2-yl-2-2-2-trifluoroacetamide-pa120321013
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rel N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2,2,2-trifluoroacetamide

Catalogue No.:PA 12 0321013
CAS :
2125942-48-3
Molecular Formula : C₃₀H₃₃F₃N₂O₄
Molecular Weight : 542.6

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Details

stdClass Object
(
    [pname] => 1-(9-Benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol
    [catalogue_number] => PA 12 0321014
    [category_ids] => ,77,69,78,70,82,
    [chemical_name] => 
    [weight] => 494.5
    [form] => C30H33Cl2NO
    [cas] => 1276121-35-7
    [pslug] => 1276121-35-7-1-9-benzylidene-2-7-dichloro-9h-fluoren-4-yl-2-dibutylamino-ethan-1-ol-pa120321014
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1-(9-Benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol

Catalogue No.:PA 12 0321014
CAS :
1276121-35-7
Molecular Formula : C₃₀H₃₃Cl₂NO
Molecular Weight : 494.5

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Details

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lopinavir

Lopinavir

192725-17-0

4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir

NA

(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid-d8

1323257-58-4

(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetyl Chloride

192800-77-4_x0000_

Lopinavir - Impurity T

1797024-56-6

(2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane

144163-85-9

Lopinavir - Impurity A

192726-05-9

Lopinavir - Impurity I

NA

Lopinavir - Impurity M

NA

(2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-trifluromethylcarbonylamino-1,6-diphenylhexane

NA

Lopinavir - Impurity S

943250-65-5

(R)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic Acid

1370045-08-1

Sulfolopinavir

NA

(S)-N-((2S,4S,5S)-4-Hydroxy-5-(2-(4-(2-(((2S,3S,5S)-3-hydroxy-5-((S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamido)-1,6-diphenylhexan-2-yl)amino)-2-oxoethoxy)-3,5-dimethylphenyl)acetamido)-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide

1989516-33-7

(S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)pentanamide

1132765-60-6

tert-Butyl ((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

192725-45-4

Abacavir Lopinavir Methylene Conjugation Impurity

NA

rel N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2,2,2-trifluoroacetamide

2125942-48-3

1-(9-Benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol

1276121-35-7

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