rivaroxaban
Chiral standards
- An anticoagulant drug used to prevent blood clots. A direct factor Xa inhibitor which is taken by mouth. An oxazolidinone derivative and structurally similar to anibiotic Linezolid.Reference standards of Rivaroxaban API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Rivaroxaban
[catalogue_number] => PA 18 38000
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[weight] => 435.88
[form] => C19H18ClN3O5S
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Catalogue No.:PA 18 38000
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
(
[pname] => Rivaroxaban - Impurity E
[catalogue_number] => PA 18 38510
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[chemical_name] =>
[weight] => 401.44
[form] => C19H19N3O5S
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Catalogue No.:PA 18 38510
Molecular Formula : C19H19N3O5S
Molecular Weight : 401.44
stdClass Object
(
[pname] => Rivaroxaban - Impurity G
[catalogue_number] => PA 18 38540
[category_ids] => ,69,71,82,78,70,
[chemical_name] =>
[weight] => 421.4
[form] => C22H19N3O6
[cas] => 446292-08-6
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stdClass Object
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[pname] => 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
[catalogue_number] => PA 18 38670
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 395.41
[form] => C21H21N3O5
[cas] => 446292-07-5
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4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
Catalogue No.:PA 18 38670
Molecular Formula : C21H21N3O5
Molecular Weight : 395.41
stdClass Object
(
[pname] => (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
[catalogue_number] => PA 18 38680
[category_ids] => ,69,71,76,75,78,70,82,88,
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[weight] => 453.9
[form] => C19H20ClN3O6S
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(S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
stdClass Object
(
[pname] => Rivaroxaban Open-Ring N-Methyl Impurity
[catalogue_number] => PA 18 38690
[category_ids] => ,88,82,78,76,75,71,70,69,
[chemical_name] =>
[weight] => 611.52
[form] => C25H24Cl2N4O6S2
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Rivaroxaban Open-Ring N-Methyl Impurity
Catalogue No.:PA 18 38690
Molecular Formula : C25H24Cl2N4O6S2
Molecular Weight : 611.52
stdClass Object
(
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[catalogue_number] => PA STI 050560
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[weight] => 399.43
[form] => C21H17D4N3O5
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4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone-d4
Catalogue No.:PA STI 050560
Molecular Formula : C21H17D4N3O5
Molecular Weight : 399.43
stdClass Object
(
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[catalogue_number] => PA STI 073540
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[weight] => 425.43
[form] => C22H15D4N3O6
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4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4
Catalogue No.:PA STI 073540
Molecular Formula : C22H15D4N3O6
Molecular Weight : 425.43
stdClass Object
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[pname] => Rivaroxaban-d4
[catalogue_number] => PA STI 078220
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[weight] => 439.91
[form] => C19H14D4ClN3O5S
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Catalogue No.:PA STI 078220
Molecular Formula : C19H14D4ClN3O5S
Molecular Weight : 439.91
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[pname] => Rivaroxaban Diol (Mixture of Diastereomers)
[catalogue_number] => PA 18 38565
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[weight] => 453.9
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Rivaroxaban Diol (Mixture of Diastereomers)
stdClass Object
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[catalogue_number] => PA 18 0381003
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[weight] => 239.66
[form] => C11H10ClNO3
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2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
Catalogue No.:PA 18 0381003
Molecular Formula : C11H10ClNO3
Molecular Weight : 239.66
stdClass Object
(
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[catalogue_number] => PA 18 0381058
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5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
Catalogue No.:PA 18 0381058
Molecular Formula : C18H19ClN4O5S
Molecular Weight : 438.88
stdClass Object
(
[pname] => Contezolid
[catalogue_number] => PA 18 0381066
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[weight] => 408.34
[form] => C18H15F3N4O4
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Catalogue No.:PA 18 0381066
Molecular Formula : C18H15F3N4O4
Molecular Weight : 408.34
stdClass Object
(
[pname] => 5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
[catalogue_number] => PA 18 0381070
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[chemical_name] =>
[weight] => 853.32
[form] => C38H37ClN6O11S2
[cas] => NA
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5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
Catalogue No.:PA 18 0381070
Molecular Formula : C38H37ClN6O11S2
Molecular Weight : 853.32
stdClass Object
(
[pname] => N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide
[catalogue_number] => PA 18 0381071
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[chemical_name] =>
[weight] => 393.84
[form] => C17H16ClN3O4S
[cas] => 482306-93-4
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N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide
Catalogue No.:PA 18 0381071
Molecular Formula : C17H16ClN3O4S
Molecular Weight : 393.84
stdClass Object
(
[pname] => 2-Chloroisoindoline-1,3-dione
[catalogue_number] => PA 18 0381072
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[chemical_name] =>
[weight] => 181.58
[form] => C8H4ClNO2
[cas] => 3481-09-2
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2-Chloroisoindoline-1,3-dione
Catalogue No.:PA 18 0381072
Molecular Formula : C8H4ClNO2
Molecular Weight : 181.58
stdClass Object
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[pname] => Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
[catalogue_number] => PA 18 0381075
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[weight] => 435.88
[form] => C19H18ClN3O5S
[cas] => 1879903-65-7
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Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
Catalogue No.:PA 18 0381075
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
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[weight] => 313.74
[form] => C13H16ClN3O4
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N-(3-Chloro-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous Amide
Catalogue No.:PA 18 0381076
Molecular Formula : C13H16ClN3O4
Molecular Weight : 313.74
stdClass Object
(
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[catalogue_number] => PA 18 0381081
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[chemical_name] =>
[weight] => 424.41
[form] => C21H20N4O6
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N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
Catalogue No.:PA 18 0381081
Molecular Formula : C21H20N4O6
Molecular Weight : 424.41
stdClass Object
(
[pname] => 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)morpholine
[catalogue_number] => PA 18 0381084
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[chemical_name] =>
[weight] => 226.24
[form] => C9H14N4O3
[cas] => 241483-00-1
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4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)morpholine
Catalogue No.:PA 18 0381084
Molecular Formula : C9H14N4O3
Molecular Weight : 226.24
stdClass Object
(
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[catalogue_number] => PA 18 0381085
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[chemical_name] =>
[weight] => 395.42
[form] => C21H21N3O5
[cas] => 1257527-98-2
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2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione
Catalogue No.:PA 18 0381085
Molecular Formula : C21H21N3O5
Molecular Weight : 395.42
stdClass Object
(
[pname] => Rivaroxaban Isomer
[catalogue_number] => PA 18 0381086
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[chemical_name] =>
[weight] => 391.87
[form] => C18H18ClN3O3S
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Catalogue No.:PA 18 0381086
Molecular Formula : C18H18ClN3O3S
Molecular Weight : 391.87
stdClass Object
(
[pname] => Rivaroxaban Open Ring Methylamine
[catalogue_number] => PA 18 0381087
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[chemical_name] =>
[weight] => 279.34
[form] => C14H21N3O3
[cas] => 2459303-14-9
[pslug] => 2459303-14-9-rivaroxaban-open-ring-methylamine-pa180381087
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Rivaroxaban Open Ring Methylamine
Catalogue No.:PA 18 0381087
Molecular Formula : C14H21N3O3
Molecular Weight : 279.34
stdClass Object
(
[pname] => Rivaroxaban Phthalimido Ethyl Ester Analog
[catalogue_number] => PA 18 0381088
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 612.05
[form] => C29H26ClN3O8S
[cas] => 2206826-56-2
[pslug] => 2206826-56-2-rivaroxaban-phthalimido-ethyl-ester-analog-pa180381088
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Rivaroxaban Phthalimido Ethyl Ester Analog
Catalogue No.:PA 18 0381088
Molecular Formula : C29H26ClN3O8S
Molecular Weight : 612.05
stdClass Object
(
[pname] => (S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)-N-methylacetamide
[catalogue_number] => PA 18 0381090
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 322.37
[form] => C15H22N4O4
[cas] => NA
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(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)-N-methylacetamide
Catalogue No.:PA 18 0381090
Molecular Formula : C15H22N4O4
Molecular Weight : 322.37
stdClass Object
(
[pname] => (S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)(nitroso)amino)ethoxy)-N-methylacetamide
[catalogue_number] => PA 18 0381091
[category_ids] => ,69,70,78,80,82,88,
[chemical_name] =>
[weight] => 351.36
[form] => C15H21N5O5
[cas] => NA
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(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)(nitroso)amino)ethoxy)-N-methylacetamide
Catalogue No.:PA 18 0381091
Molecular Formula : C15H21N5O5
Molecular Weight : 351.36
stdClass Object
(
[pname] => 1-(4-Chlorothiophen-2-yl)ethan-1-one
[catalogue_number] => PA 18 0381092
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 160.62
[form] => C6H5ClOS
[cas] => 34730-20-6
[pslug] => 34730-20-6-1-4-chlorothiophen-2-yl-ethan-1-one-pa180381092
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1-(4-Chlorothiophen-2-yl)ethan-1-one
Catalogue No.:PA 18 0381092
Molecular Formula : C6H5ClOS
Molecular Weight : 160.62
stdClass Object
(
[pname] => (S)-N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
[catalogue_number] => PA 18 0381095
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[chemical_name] =>
[weight] => 424.41
[form] => C21H20N4O6
[cas] => NA
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(S)-N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
Catalogue No.:PA 18 0381095
Molecular Formula : C21H20N4O6
Molecular Weight : 424.41
stdClass Object
(
[pname] => (S)-2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione
[catalogue_number] => PA 18 0381096
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 221.21
[form] => C11H11NO4
[cas] => 119835-88-0
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(S)-2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione
Catalogue No.:PA 18 0381096
Molecular Formula : C11H11NO4
Molecular Weight : 221.21
stdClass Object
(
[pname] => 2,4-Dimethoxy-5-nitroaniline
[catalogue_number] => PA 18 0381098
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 198.18
[form] => C8H10N2O4
[cas] => 70904-65-3
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2,4-Dimethoxy-5-nitroaniline
Catalogue No.:PA 18 0381098
Molecular Formula : C8H10N2O4
Molecular Weight : 198.18
stdClass Object
(
[pname] => (E)-5-Chloro-N-(3-((4-(3-oxomorpholino)phenyl)amino)prop-1-en-1-yl)thiophene-2-carboxamide
[catalogue_number] => PA 18 0381099
[category_ids] => ,69,71,78,70,82,
[chemical_name] =>
[weight] => 391.87
[form] => C18H18ClN3O3S
[cas] => NA
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(E)-5-Chloro-N-(3-((4-(3-oxomorpholino)phenyl)amino)prop-1-en-1-yl)thiophene-2-carboxamide
Catalogue No.:PA 18 0381099
Molecular Formula : C18H18ClN3O3S
Molecular Weight : 391.87