rivaroxaban

Chiral standards - An anticoagulant drug used to prevent blood clots. A direct factor Xa inhibitor which is taken by mouth. An oxazolidinone derivative and structurally similar to anibiotic Linezolid.Reference standards of Rivaroxaban API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Rivaroxaban
    [catalogue_number] => PA 18 38000
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 366789-02-8
    [pslug] => 366789-02-8-rivaroxaban-api-standards-pa1838000
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PA 18 38000
PA 18 38000

Rivaroxaban


  • Catalogue No.:PA 18 38000

  • CAS :

    366789-02-8

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => Rivaroxaban - Impurity E
    [catalogue_number] => PA 18 38510
    [category_ids] => ,69,70,71,78,82,88,
    [chemical_name] => 
    [weight] => 401.44
    [form] => C19H19N3O5S
    [cas] => 1415566-28-7
    [pslug] => 1415566-28-7-rivaroxaban-impurity-e-pa1838510
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PA 18 38510
PA 18 38510

Rivaroxaban - Impurity E


  • Catalogue No.:PA 18 38510

  • CAS :

    1415566-28-7

  • Molecular Formula : C19H19N3O5S

  • Molecular Weight : 401.44

stdClass Object
(
    [pname] => Rivaroxaban - Impurity G
    [catalogue_number] => PA 18 38540
    [category_ids] => ,69,71,82,78,70,
    [chemical_name] => 
    [weight] => 421.4
    [form] => C22H19N3O6
    [cas] => 446292-08-6
    [pslug] => 446292-08-6-rivaroxaban-impurity-g-pa1838540
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PA 18 38540
PA 18 38540

Rivaroxaban - Impurity G


  • Catalogue No.:PA 18 38540

  • CAS :

    446292-08-6

  • Molecular Formula : C22H19N3O6

  • Molecular Weight : 421.4

stdClass Object
(
    [pname] => 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
    [catalogue_number] => PA 18 38670
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 395.41
    [form] => C21H21N3O5
    [cas] => 446292-07-5
    [pslug] => 446292-07-5-4-2r-hydroxy-3-phthalimido-propylamine-phenyl-3-morpholinone-pa1838670
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PA 18 38670
PA 18 38670

4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone


  • Catalogue No.:PA 18 38670

  • CAS :

    446292-07-5

  • Molecular Formula : C21H21N3O5

  • Molecular Weight : 395.41

stdClass Object
(
    [pname] => (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
    [catalogue_number] => PA 18 38680
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 931204-39-6
    [pslug] => 931204-39-6-s-2-2-4-5-5-chlorothiophene-2-carboxamido-methyl-2-oxooxazolidin-3-yl-phenyl-amino-ethoxy-acetic-acid-pa1838680
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PA 18 38680
PA 18 38680

(S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid


  • Catalogue No.:PA 18 38680

  • CAS :

    931204-39-6

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
(
    [pname] => Rivaroxaban Open-Ring N-Methyl Impurity
    [catalogue_number] => PA 18 38690
    [category_ids] => ,88,82,78,76,75,71,70,69,
    [chemical_name] => 
    [weight] => 611.52
    [form] => C25H24Cl2N4O6S2
    [cas] => 1807455-76-0
    [pslug] => 1807455-76-0-rivaroxaban-open-ring-n-methyl-impurity-pa1838690
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PA 18 38690
PA 18 38690

Rivaroxaban Open-Ring N-Methyl Impurity


  • Catalogue No.:PA 18 38690

  • CAS :

    1807455-76-0

  • Molecular Formula : C25H24Cl2N4O6S2

  • Molecular Weight : 611.52

stdClass Object
(
    [pname] => 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone-d4
    [catalogue_number] => PA STI 050560
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 399.43
    [form] => C21H17D4N3O5
    [cas] => 1329838-35-8
    [pslug] => 1329838-35-8-4-2r-hydroxy-3-phthalimido-propylamine-phenyl-3-morpholinone-d4-pasti050560
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PA STI 050560
PA STI 050560

4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone-d4


  • Catalogue No.:PA STI 050560

  • CAS :

    1329838-35-8

  • Molecular Formula : C21H17D4N3O5

  • Molecular Weight : 399.43

stdClass Object
(
    [pname] => 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4
    [catalogue_number] => PA STI 073540
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 425.43
    [form] => C22H15D4N3O6
    [cas] => 1330180-09-0
    [pslug] => 1330180-09-0-4-4-5s-5-phthalimidomethyl-2-oxo-3-oxazolidinyl-phenyl-3-morpholinone-d4-pasti073540
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PA STI 073540
PA STI 073540

4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4


  • Catalogue No.:PA STI 073540

  • CAS :

    1330180-09-0

  • Molecular Formula : C22H15D4N3O6

  • Molecular Weight : 425.43

stdClass Object
(
    [pname] => Rivaroxaban-d4
    [catalogue_number] => PA STI 078220
    [category_ids] => ,69,71,98,78,70,82,88,
    [chemical_name] => 
    [weight] => 439.91
    [form] => C19H14D4ClN3O5S
    [cas] => 1132681-38-9
    [pslug] => 1132681-38-9-rivaroxaban-d4-pasti078220
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PA STI 078220
PA STI 078220

Rivaroxaban-d4


  • Catalogue No.:PA STI 078220

  • CAS :

    1132681-38-9

  • Molecular Formula : C19H14D4ClN3O5S

  • Molecular Weight : 439.91

stdClass Object
(
    [pname] => Rivaroxaban Diol (Mixture of Diastereomers)
    [catalogue_number] => PA 18 38565
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 1160170-00-2
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PA 18 38565
PA 18 38565

Rivaroxaban Diol (Mixture of Diastereomers)


  • Catalogue No.:PA 18 38565

  • CAS :

    1160170-00-2

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
(
    [pname] => 2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
    [catalogue_number] => PA 18 0381003
    [category_ids] => ,75,76,70,78,82,69,
    [chemical_name] => 
    [weight] => 239.66
    [form] => C11H10ClNO3
    [cas] => 148857-42-5
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PA 18 0381003
PA 18 0381003

2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione


  • Catalogue No.:PA 18 0381003

  • CAS :

    148857-42-5

  • Molecular Formula : C11H10ClNO3

  • Molecular Weight : 239.66

stdClass Object
(
    [pname] => 5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381058
    [category_ids] => ,69,70,71,78,82,88,162,
    [chemical_name] => 
    [weight] => 438.88
    [form] => C18H19ClN4O5S
    [cas] => NA
    [pslug] => 5-chloro-n-2-hydroxy-3-nitroso-4-3-oxomorpholino-phenyl-amino-propyl-thiophene-2-carboxamide-pa180381058
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PA 18 0381058
PA 18 0381058

5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381058

  • CAS :

    NA

  • Molecular Formula : C18H19ClN4O5S

  • Molecular Weight : 438.88

stdClass Object
(
    [pname] => Contezolid
    [catalogue_number] => PA 18 0381066
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 408.34
    [form] => C18H15F3N4O4
    [cas] => 1112968-42-9
    [pslug] => 1112968-42-9-contezolid-pa180381066
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PA 18 0381066
PA 18 0381066

Contezolid


  • Catalogue No.:PA 18 0381066

  • CAS :

    1112968-42-9

  • Molecular Formula : C18H15F3N4O4

  • Molecular Weight : 408.34

stdClass Object
(
    [pname] => 5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381070
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 853.32
    [form] => C38H37ClN6O11S2
    [cas] => NA
    [pslug] => 5-chloro-n-4-s-5-5-hydroxythiophene-2-carboxamido-methyl-2-oxooxazolidin-3-yl-phenyl-n-2-2-oxo-2-s-2-oxo-3-4-3-oxomorpholino-phenyl-oxazolidin-5-yl-methyl-amino-ethoxy-ethyl-thiophene-2-carboxamide-pa180381070
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PA 18 0381070
PA 18 0381070

5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381070

  • CAS :

    NA

  • Molecular Formula : C38H37ClN6O11S2

  • Molecular Weight : 853.32

stdClass Object
(
    [pname] => N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide
    [catalogue_number] => PA 18 0381071
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 393.84
    [form] => C17H16ClN3O4S
    [cas] => 482306-93-4
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PA 18 0381071
PA 18 0381071

N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide


  • Catalogue No.:PA 18 0381071

  • CAS :

    482306-93-4

  • Molecular Formula : C17H16ClN3O4S

  • Molecular Weight : 393.84

stdClass Object
(
    [pname] => 2-Chloroisoindoline-1,3-dione
    [catalogue_number] => PA 18 0381072
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 181.58
    [form] => C8H4ClNO2
    [cas] => 3481-09-2
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PA 18 0381072
PA 18 0381072

2-Chloroisoindoline-1,3-dione


  • Catalogue No.:PA 18 0381072

  • CAS :

    3481-09-2

  • Molecular Formula : C8H4ClNO2

  • Molecular Weight : 181.58

stdClass Object
(
    [pname] => Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
    [catalogue_number] => PA 18 0381075
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 1879903-65-7
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PA 18 0381075
PA 18 0381075

Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity


  • Catalogue No.:PA 18 0381075

  • CAS :

    1879903-65-7

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => N-(3-Chloro-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous Amide
    [catalogue_number] => PA 18 0381076
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 313.74
    [form] => C13H16ClN3O4
    [cas] => NA
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PA 18 0381076
PA 18 0381076

N-(3-Chloro-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous Amide


  • Catalogue No.:PA 18 0381076

  • CAS :

    NA

  • Molecular Formula : C13H16ClN3O4

  • Molecular Weight : 313.74

stdClass Object
(
    [pname] => N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
    [catalogue_number] => PA 18 0381081
    [category_ids] => ,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 424.41
    [form] => C21H20N4O6
    [cas] => NA
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PA 18 0381081
PA 18 0381081

N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide


  • Catalogue No.:PA 18 0381081

  • CAS :

    NA

  • Molecular Formula : C21H20N4O6

  • Molecular Weight : 424.41

stdClass Object
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    [pname] => 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)morpholine
    [catalogue_number] => PA 18 0381084
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 226.24
    [form] => C9H14N4O3
    [cas] => 241483-00-1
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PA 18 0381084
PA 18 0381084

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)morpholine


  • Catalogue No.:PA 18 0381084

  • CAS :

    241483-00-1

  • Molecular Formula : C9H14N4O3

  • Molecular Weight : 226.24

stdClass Object
(
    [pname] => 2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione
    [catalogue_number] => PA 18 0381085
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 395.42
    [form] => C21H21N3O5
    [cas] => 1257527-98-2
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PA 18 0381085
PA 18 0381085

2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione


  • Catalogue No.:PA 18 0381085

  • CAS :

    1257527-98-2

  • Molecular Formula : C21H21N3O5

  • Molecular Weight : 395.42

stdClass Object
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    [pname] => Rivaroxaban Isomer
    [catalogue_number] => PA 18 0381086
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 391.87
    [form] => C18H18ClN3O3S
    [cas] => 2310316-95-9
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PA 18 0381086
PA 18 0381086

Rivaroxaban Isomer


  • Catalogue No.:PA 18 0381086

  • CAS :

    2310316-95-9

  • Molecular Formula : C18H18ClN3O3S

  • Molecular Weight : 391.87

stdClass Object
(
    [pname] => Rivaroxaban Open Ring Methylamine
    [catalogue_number] => PA 18 0381087
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 279.34
    [form] => C14H21N3O3
    [cas] => 2459303-14-9
    [pslug] => 2459303-14-9-rivaroxaban-open-ring-methylamine-pa180381087
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PA 18 0381087
PA 18 0381087

Rivaroxaban Open Ring Methylamine


  • Catalogue No.:PA 18 0381087

  • CAS :

    2459303-14-9

  • Molecular Formula : C14H21N3O3

  • Molecular Weight : 279.34

stdClass Object
(
    [pname] => Rivaroxaban Phthalimido Ethyl Ester Analog
    [catalogue_number] => PA 18 0381088
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 612.05
    [form] => C29H26ClN3O8S
    [cas] => 2206826-56-2
    [pslug] => 2206826-56-2-rivaroxaban-phthalimido-ethyl-ester-analog-pa180381088
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PA 18 0381088
PA 18 0381088

Rivaroxaban Phthalimido Ethyl Ester Analog


  • Catalogue No.:PA 18 0381088

  • CAS :

    2206826-56-2

  • Molecular Formula : C29H26ClN3O8S

  • Molecular Weight : 612.05

stdClass Object
(
    [pname] => (S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)-N-methylacetamide
    [catalogue_number] => PA 18 0381090
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 322.37
    [form] => C15H22N4O4
    [cas] => NA
    [pslug] => s-2-2-4-5-aminomethyl-2-oxooxazolidin-3-yl-phenyl-amino-ethoxy-n-methylacetamide-pa180381090
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PA 18 0381090
PA 18 0381090

(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)-N-methylacetamide


  • Catalogue No.:PA 18 0381090

  • CAS :

    NA

  • Molecular Formula : C15H22N4O4

  • Molecular Weight : 322.37

stdClass Object
(
    [pname] => (S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)(nitroso)amino)ethoxy)-N-methylacetamide
    [catalogue_number] => PA 18 0381091
    [category_ids] => ,69,70,78,80,82,88,
    [chemical_name] => 
    [weight] => 351.36
    [form] => C15H21N5O5
    [cas] => NA
    [pslug] => s-2-2-4-5-aminomethyl-2-oxooxazolidin-3-yl-phenyl-nitroso-amino-ethoxy-n-methylacetamide-pa180381091
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PA 18 0381091
PA 18 0381091

(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)(nitroso)amino)ethoxy)-N-methylacetamide


  • Catalogue No.:PA 18 0381091

  • CAS :

    NA

  • Molecular Formula : C15H21N5O5

  • Molecular Weight : 351.36

stdClass Object
(
    [pname] => 1-(4-Chlorothiophen-2-yl)ethan-1-one
    [catalogue_number] => PA 18 0381092
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 160.62
    [form] => C6H5ClOS
    [cas] => 34730-20-6
    [pslug] => 34730-20-6-1-4-chlorothiophen-2-yl-ethan-1-one-pa180381092
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PA 18 0381092
PA 18 0381092

1-(4-Chlorothiophen-2-yl)ethan-1-one


  • Catalogue No.:PA 18 0381092

  • CAS :

    34730-20-6

  • Molecular Formula : C6H5ClOS

  • Molecular Weight : 160.62

stdClass Object
(
    [pname] => (S)-N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
    [catalogue_number] => PA 18 0381095
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 424.41
    [form] => C21H20N4O6
    [cas] => NA
    [pslug] => s-n-3-1-3-dioxoisoindolin-2-yl-2-hydroxypropyl-n-4-3-oxomorpholino-phenyl-nitrous-amide-pa180381095
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PA 18 0381095
PA 18 0381095

(S)-N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide


  • Catalogue No.:PA 18 0381095

  • CAS :

    NA

  • Molecular Formula : C21H20N4O6

  • Molecular Weight : 424.41

stdClass Object
(
    [pname] => (S)-2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione
    [catalogue_number] => PA 18 0381096
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 221.21
    [form] => C11H11NO4
    [cas] => 119835-88-0
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PA 18 0381096
PA 18 0381096

(S)-2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione


  • Catalogue No.:PA 18 0381096

  • CAS :

    119835-88-0

  • Molecular Formula : C11H11NO4

  • Molecular Weight : 221.21

stdClass Object
(
    [pname] => 2,4-Dimethoxy-5-nitroaniline
    [catalogue_number] => PA 18 0381098
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 198.18
    [form] => C8H10N2O4
    [cas] => 70904-65-3
    [pslug] => 70904-65-3-2-4-dimethoxy-5-nitroaniline-pa180381098
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PA 18 0381098
PA 18 0381098

2,4-Dimethoxy-5-nitroaniline


  • Catalogue No.:PA 18 0381098

  • CAS :

    70904-65-3

  • Molecular Formula : C8H10N2O4

  • Molecular Weight : 198.18

stdClass Object
(
    [pname] => (E)-5-Chloro-N-(3-((4-(3-oxomorpholino)phenyl)amino)prop-1-en-1-yl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381099
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 391.87
    [form] => C18H18ClN3O3S
    [cas] => NA
    [pslug] => e-5-chloro-n-3-4-3-oxomorpholino-phenyl-amino-prop-1-en-1-yl-thiophene-2-carboxamide-pa180381099
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PA 18 0381099
PA 18 0381099

(E)-5-Chloro-N-(3-((4-(3-oxomorpholino)phenyl)amino)prop-1-en-1-yl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381099

  • CAS :

    NA

  • Molecular Formula : C18H18ClN3O3S

  • Molecular Weight : 391.87

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