Apixaban-impurities | Pharmaffiliates

apixaban

Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
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    [pname] => Apixaban - API Standards 
    [catalogue_number] => PA 28 11000
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 459.50
    [form] => C25H25N5O4
    [cas] => 503612-47-3
    [pslug] => 503612-47-3-apixaban-api-pa2811000
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PA 28 11000

Apixaban - API Standards


  • Catalogue No.:PA 28 11000

  • CAS :

    503612-47-3

  • Molecular Formula : C25H25N5O4

  • Molecular Weight : 459.50

stdClass Object
(
    [pname] => O-Desmethyl Apixaban
    [catalogue_number] => PA 28 11510
    [category_ids] => ,80,71,81,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 445.47
    [form] => C24H23N5O4
    [cas] => 503612-76-8
    [pslug] => 503612-76-8-o-desmethyl-apixaban-pa2811510
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PA 28 11510

O-Desmethyl Apixaban


  • Catalogue No.:PA 28 11510

  • CAS :

    503612-76-8

  • Molecular Formula : C24H23N5O4

  • Molecular Weight : 445.47

stdClass Object
(
    [pname] => 1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one
    [catalogue_number] => PA 28 0111057
    [category_ids] => ,80,71,81,78,82,
    [chemical_name] => 
    [weight] => 222.67
    [form] => C11H11ClN2O
    [cas] => 1801881-15-1
    [pslug] => 1801881-15-1-1-4-aminophenyl-3-chloro-5-6-dihydropyridin-2-1h-one-pa280111057
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PA 28 0111057

1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 0111057

  • CAS :

    1801881-15-1

  • Molecular Formula : C11H11ClN2O

  • Molecular Weight : 222.67

stdClass Object
(
    [pname] => 1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
    [catalogue_number] => PA 28 0111060
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 546.63
    [form] => C29H34N6O5
    [cas] => NA
    [pslug] => 1-4-methoxyphenyl-7a-morpholino-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-3a-4-5-6-7-7a-hexahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxamide-pa280111060
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PA 28 0111060

1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 0111060

  • CAS :

    NA

  • Molecular Formula : C29H34N6O5

  • Molecular Weight : 546.63

stdClass Object
(
    [pname] => 1-(3-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
    [catalogue_number] => PA 28 0111061
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 273.34
    [form] => C15H19N3O2
    [cas] => 2437650-75-2
    [pslug] => 2437650-75-2-1-3-aminophenyl-3-morpholino-5-6-dihydropyridin-2-1h-one-pa280111061
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PA 28 0111061

1-(3-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 0111061

  • CAS :

    2437650-75-2

  • Molecular Formula : C15H19N3O2

  • Molecular Weight : 273.34

stdClass Object
(
    [pname] => 1-(4-Aminophenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111062
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 190.25
    [form] => C11H14N2O
    [cas] => 438056-68-9
    [pslug] => 438056-68-9-1-4-aminophenyl-piperidin-2-one-pa280111062
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PA 28 0111062

1-(4-Aminophenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111062

  • CAS :

    438056-68-9

  • Molecular Formula : C11H14N2O

  • Molecular Weight : 190.25

stdClass Object
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    [pname] => Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111065
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 488.54
    [form] => C27H28N4O5
    [cas] => 1801881-20-8
    [pslug] => 1801881-20-8-ethyl-1-2-methoxyphenyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111065
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PA 28 0111065

Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111065

  • CAS :

    1801881-20-8

  • Molecular Formula : C27H28N4O5

  • Molecular Weight : 488.54

stdClass Object
(
    [pname] => Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111066
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 458.52
    [form] => C26H26N4O4
    [cas] => 1801881-21-9
    [pslug] => 1801881-21-9-ethyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-1-phenyl-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111066
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PA 28 0111066

Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111066

  • CAS :

    1801881-21-9

  • Molecular Formula : C26H26N4O4

  • Molecular Weight : 458.52

stdClass Object
(
    [pname] => 5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid
    [catalogue_number] => PA 28 0111067
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 402.45
    [form] => C20H26N4O5
    [cas] => NA
    [pslug] => 5-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-nitroso-amino-pentanoic-acid-pa280111067
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PA 28 0111067

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid


  • Catalogue No.:PA 28 0111067

  • CAS :

    NA

  • Molecular Formula : C20H26N4O5

  • Molecular Weight : 402.45

stdClass Object
(
    [pname] => 5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide
    [catalogue_number] => PA 28 0111068
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 420.89
    [form] => C20H25ClN4O4
    [cas] => NA
    [pslug] => 5-chloro-n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-n-nitrosopentanamide-pa280111068
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PA 28 0111068

5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide


  • Catalogue No.:PA 28 0111068

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

stdClass Object
(
    [pname] => N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide
    [catalogue_number] => PA 28 0111071
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 301.35
    [form] => C16H19N3O3
    [cas] => NA
    [pslug] => n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-formamide-pa280111071
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PA 28 0111071

N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide


  • Catalogue No.:PA 28 0111071

  • CAS :

    NA

  • Molecular Formula : C16H19N3O3

  • Molecular Weight : 301.35

stdClass Object
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    [pname] => 3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111072
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 357.45
    [form] => C20H27N3O3
    [cas] => NA
    [pslug] => 3-morpholino-1-3-2-oxopiperidin-1-yl-phenyl-piperidin-2-one-pa280111072
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PA 28 0111072

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111072

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

stdClass Object
(
    [pname] => 3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111073
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 357.45
    [form] => C20H27N3O3
    [cas] => NA
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PA 28 0111073

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111073

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

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    [pname] => Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111074
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 486.53
    [form] => C27H26N4O5
    [cas] => 2514951-00-7
    [pslug] => 2514951-00-7-ethyl-1-4-methoxyphenyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-6-7-dihydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111074
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PA 28 0111074

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111074

  • CAS :

    2514951-00-7

  • Molecular Formula : C27H26N4O5

  • Molecular Weight : 486.53