bortezomib
Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.. Reference standards of Bortezomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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Bortezomib - API Standards
Catalogue No.:PA 02 79000
Molecular Formula : C19H25BN4O4
Molecular Weight : 384.24
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Bortezomib (1S,2R)-Isomer
Catalogue No.:PA 02 79530
Molecular Formula : C19H25BN4O4
Molecular Weight : 384.24
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Bortezomib Amide analog (R-Isomer)
Catalogue No.:PA 02 0791040
Molecular Formula : C14H14N4O2
Molecular Weight : 270.29
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N-(1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79540
Molecular Formula : C19H24N4O3
Molecular Weight : 356.42
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Bortezomib Amide analog (Mixture of isomers)
Catalogue No.:PA 02 79550
Molecular Formula : C14H14N4O2
Molecular Weight : 270.29
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N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Catalogue No.:PA 02 79560
Molecular Formula : C19H24N4O2
Molecular Weight : 340.42
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(R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid
Catalogue No.:PA 02 79570
Molecular Formula : C10H16BN3O3
Molecular Weight : 237.06
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N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79580
Molecular Formula : C19H24N4O2
Molecular Weight : 340.42
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(4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
Catalogue No.:PA 02 79590
Molecular Formula : C18H23BN4O5
Molecular Weight : 386.21
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N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79600
Molecular Formula : C28H37BN4O4
Molecular Weight : 504.43
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(R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
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Catalogue No.:PA 02 79630
Molecular Formula : C19H25BN4O5
Molecular Weight : 400.24
stdClass Object
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[pname] => Bortezomib-D8 (Major)
[catalogue_number] => PA STI 014210
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Catalogue No.:PA STI 014210
Molecular Formula : C19H17D8BN4O4
Molecular Weight : 392.29
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[catalogue_number] => PA STI 014220
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Catalogue No.:PA STI 014220
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
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Catalogue No.:PA STI 014230
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
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Catalogue No.:PA STI 014240
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
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N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791038
Molecular Formula : C19H24N4O3
Molecular Weight : 356.43