Palbociclib-impurities | Pharmaffiliates

palbociclib

Palbociclib is a drug which is used to treat a certain type of breast cancer. Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.Reference standards of Palbociclib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Palbociclib - API Standards 
    [catalogue_number] => PA 43 06000
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 447.53
    [form] => C24H29N7O2
    [cas] => 571190-30-2
    [pslug] => 571190-30-2-palbociclib-api-pa4306000
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PA 43 06000

Palbociclib - API Standards


  • Catalogue No.:PA 43 06000

  • CAS :

    571190-30-2

  • Molecular Formula : C24H29N7O2

  • Molecular Weight : 447.53

stdClass Object
(
    [pname] => Palbociclib N-oxide
    [catalogue_number] => PA 43 06510
    [category_ids] => 82,81,79,78,75,71,70,80
    [chemical_name] => 
    [weight] => 463.53
    [form] => C24H29N7O3
    [cas] => 2174002-29-8
    [pslug] => 2174002-29-8-palbociclib-n-oxide-pa4306510
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PA 43 06510

Palbociclib N-oxide


  • Catalogue No.:PA 43 06510

  • CAS :

    2174002-29-8

  • Molecular Formula : C24H29N7O3

  • Molecular Weight : 463.53

stdClass Object
(
    [pname] => 2-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide
    [catalogue_number] => PA 43 06520
    [category_ids] => ,79,80,71,81,78,70,82,75,
    [chemical_name] => 
    [weight] => 463.53
    [form] => C24H29N7O3
    [cas] => 2098673-40-4
    [pslug] => 2098673-40-4-2-6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7-8-dihydropyrido-2-3-d-pyrimidin-2-yl-amino-5-piperazin-1-yl-pyridine-1-oxide-pa4306520
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PA 43 06520

2-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide


  • Catalogue No.:PA 43 06520

  • CAS :

    2098673-40-4

  • Molecular Formula : C24H29N7O3

  • Molecular Weight : 463.53

stdClass Object
(
    [pname] => Desoxo-palbociclib
    [catalogue_number] => PA 43 06530
    [category_ids] => ,79,80,71,81,78,70,82,75,
    [chemical_name] => 
    [weight] => 431.53
    [form] => C24H29N7O
    [cas] => 2204863-06-7
    [pslug] => 2204863-06-7-desoxo-palbociclib-pa4306530
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PA 43 06530

Desoxo-palbociclib


  • Catalogue No.:PA 43 06530

  • CAS :

    2204863-06-7

  • Molecular Formula : C24H29N7O

  • Molecular Weight : 431.53

stdClass Object
(
    [pname] => 2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic Acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
    [catalogue_number] => PA 43 06540
    [category_ids] => ,79,80,71,81,78,70,82,75,
    [chemical_name] => 
    [weight] => 603.75
    [form] => C33H45N7O4
    [cas] => 827022-35-5
    [pslug] => 827022-35-5-2-3-5-dichlorophenyl-1-3-benzoxazole-6-carboxylic-acid-2r-3r-4r-5s-6-methylamino-hexane-1-2-3-4-5-pentol-pa4306540
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PA 43 06540

2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic Acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol


  • Catalogue No.:PA 43 06540

  • CAS :

    827022-35-5

  • Molecular Formula : C33H45N7O4

  • Molecular Weight : 603.75

stdClass Object
(
    [pname] => Palbociclib-d8
    [catalogue_number] => PA STI 071181
    [category_ids] => ,79,80,71,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 455.58
    [form] => C24H21D8N7O2
    [cas] => 1628752-83-9
    [pslug] => 1628752-83-9-palbociclib-d8-pasti071181
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PA STI 071181

Palbociclib-d8


  • Catalogue No.:PA STI 071181

  • CAS :

    1628752-83-9

  • Molecular Formula : C24H21D8N7O2

  • Molecular Weight : 455.58

stdClass Object
(
    [pname] => 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
    [catalogue_number] => PA 43 06550
    [category_ids] => ,81,75,78,
    [chemical_name] => 
    [weight] => 276.56
    [form] => C9H11BrClN3
    [cas] => 1823404-28-9
    [pslug] => 1823404-28-9-5-bromo-4-chloro-n-cyclopentylpyrimidin-2-amine-pa4306550
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PA 43 06550

5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine


  • Catalogue No.:PA 43 06550

  • CAS :

    1823404-28-9

  • Molecular Formula : C9H11BrClN3

  • Molecular Weight : 276.56

stdClass Object
(
    [pname] => 6-Bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 06560
    [category_ids] => ,81,75,78,
    [chemical_name] => 
    [weight] => 324.18
    [form] => C13H14BrN3O2
    [cas] => 1922954-32-2
    [pslug] => 1922954-32-2-6-bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-pa4306560
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PA 43 06560

6-Bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one


  • Catalogue No.:PA 43 06560

  • CAS :

    1922954-32-2

  • Molecular Formula : C13H14BrN3O2

  • Molecular Weight : 324.18

stdClass Object
(
    [pname] => 6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione
    [catalogue_number] => PA 43 0061000
    [category_ids] => ,79,80,75,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 287.32
    [form] => C15H17N3O3
    [cas] => 2172256-78-7
    [pslug] => 2172256-78-7-6-acetyl-8-cyclopentyl-5-methylpyrido-2-3-d-pyrimidine-2-7-3h-8h-dione-pa430061000
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PA 43 0061000

6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione


  • Catalogue No.:PA 43 0061000

  • CAS :

    2172256-78-7

  • Molecular Formula : C15H17N3O3

  • Molecular Weight : 287.32

stdClass Object
(
    [pname] => Palbociclib Tri-O-isobutyryl-β-D-glucuronic Acid Methyl Ester
    [catalogue_number] => PA 43 0061048
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 847.97
    [form] => C43H57N7O11
    [cas] => NA
    [pslug] => palbociclib-tri-o-isobutyryl-beta-d-glucuronic-acid-methyl-ester-pa430061048
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PA 43 0061048

Palbociclib Tri-O-isobutyryl-β-D-glucuronic Acid Methyl Ester


  • Catalogue No.:PA 43 0061048

  • CAS :

    NA

  • Molecular Formula : C43H57N7O11

  • Molecular Weight : 847.97

stdClass Object
(
    [pname] => 6-Acetyl-2-((5-aminopyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061049
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 378.44
    [form] => C20H22N6O2
    [cas] => 2363172-64-7
    [pslug] => 2363172-64-7-6-acetyl-2-5-aminopyridin-2-yl-amino-8-cyclopentyl-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-pa430061049
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PA 43 0061049

6-Acetyl-2-((5-aminopyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one


  • Catalogue No.:PA 43 0061049

  • CAS :

    2363172-64-7

  • Molecular Formula : C20H22N6O2

  • Molecular Weight : 378.44

stdClass Object
(
    [pname] => Tert-butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate
    [catalogue_number] => PA 43 0061050
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 308.34
    [form] => C14H20N4O4
    [cas] => 1779124-68-3
    [pslug] => 1779124-68-3-tert-butyl-4-2-nitropyridin-3-yl-piperazine-1-carboxylate-pa430061050
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PA 43 0061050

Tert-butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate


  • Catalogue No.:PA 43 0061050

  • CAS :

    1779124-68-3

  • Molecular Formula : C14H20N4O4

  • Molecular Weight : 308.34

stdClass Object
(
    [pname] => 4,4'-Bis(6-nitropyridin-3-yl)-1,1'-bipiperazine
    [catalogue_number] => PA 43 0061051
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 414.43
    [form] => C18H22N8O4
    [cas] => NA
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PA 43 0061051

4,4'-Bis(6-nitropyridin-3-yl)-1,1'-bipiperazine


  • Catalogue No.:PA 43 0061051

  • CAS :

    NA

  • Molecular Formula : C18H22N8O4

  • Molecular Weight : 414.43

stdClass Object
(
    [pname] => Di-tert-butyl 4,4'-(diazene-1,2-diylbis(pyridine-6,3-diyl))bis(piperazine-1-carboxylate)
    [catalogue_number] => PA 43 0061052
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 552.68
    [form] => C28H40N8O4
    [cas] => 2399424-46-3
    [pslug] => 2399424-46-3-di-tert-butyl-4-4-diazene-1-2-diylbis-pyridine-6-3-diyl-bis-piperazine-1-carboxylate-pa430061052
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PA 43 0061052

Di-tert-butyl 4,4'-(diazene-1,2-diylbis(pyridine-6,3-diyl))bis(piperazine-1-carboxylate)


  • Catalogue No.:PA 43 0061052

  • CAS :

    2399424-46-3

  • Molecular Formula : C28H40N8O4

  • Molecular Weight : 552.68

stdClass Object
(
    [pname] => tert-Butyl 4-(6-(hydroxyamino)pyridin-3-yl)piperazine-1-carboxylate
    [catalogue_number] => PA 43 0061053
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 294.36
    [form] => C14H22N4O3
    [cas] => NA
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PA 43 0061053

tert-Butyl 4-(6-(hydroxyamino)pyridin-3-yl)piperazine-1-carboxylate


  • Catalogue No.:PA 43 0061053

  • CAS :

    NA

  • Molecular Formula : C14H22N4O3

  • Molecular Weight : 294.36

stdClass Object
(
    [pname] => N-(5-(Piperazin-1-yl)pyridin-2-yl)hydroxylamine
    [catalogue_number] => PA 43 0061054
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 194.24
    [form] => C9H14N4O
    [cas] => NA
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PA 43 0061054

N-(5-(Piperazin-1-yl)pyridin-2-yl)hydroxylamine


  • Catalogue No.:PA 43 0061054

  • CAS :

    NA

  • Molecular Formula : C9H14N4O

  • Molecular Weight : 194.24

stdClass Object
(
    [pname] => 5-Brom-2-nitro-pyridin-1-Oxide
    [catalogue_number] => PA 43 0061055
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 218.99
    [form] => C5H3BrN2O3
    [cas] => 27412-69-7
    [pslug] => 27412-69-7-5-brom-2-nitro-pyridin-1-oxide-pa430061055
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PA 43 0061055

5-Brom-2-nitro-pyridin-1-Oxide


  • Catalogue No.:PA 43 0061055

  • CAS :

    27412-69-7

  • Molecular Formula : C5H3BrN2O3

  • Molecular Weight : 218.99

stdClass Object
(
    [pname] => 3,5-Dibromo-2-nitropyridine
    [catalogue_number] => PA 43 0061056
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 281.89
    [form] => C5H2Br2N2O2
    [cas] => 610261-34-2
    [pslug] => 610261-34-2-3-5-dibromo-2-nitropyridine-pa430061056
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PA 43 0061056

3,5-Dibromo-2-nitropyridine


  • Catalogue No.:PA 43 0061056

  • CAS :

    610261-34-2

  • Molecular Formula : C5H2Br2N2O2

  • Molecular Weight : 281.89

stdClass Object
(
    [pname] => Palbociclib Maleic Acid Adduct
    [catalogue_number] => PA 43 0061062
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 545.6
    [form] => C28H31N7O5
    [cas] => NA
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PA 43 0061062

Palbociclib Maleic Acid Adduct


  • Catalogue No.:PA 43 0061062

  • CAS :

    NA

  • Molecular Formula : C28H31N7O5

  • Molecular Weight : 545.6

stdClass Object
(
    [pname] => 1-(6-Nitropyridin-3-yl)-4-nitrosopiperazine
    [catalogue_number] => PA 43 0061063
    [category_ids] => ,70,71,78,79,80,81,82,162,
    [chemical_name] => 
    [weight] => 237.22
    [form] => C9H11N5O3
    [cas] => 2089333-12-8
    [pslug] => 2089333-12-8-1-6-nitropyridin-3-yl-4-nitrosopiperazine-pa430061063
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PA 43 0061063

1-(6-Nitropyridin-3-yl)-4-nitrosopiperazine


  • Catalogue No.:PA 43 0061063

  • CAS :

    2089333-12-8

  • Molecular Formula : C9H11N5O3

  • Molecular Weight : 237.22