Bendamustine Hydrochloride-Impurities | Pharmaffiliates

bendamustine hydrochloride

An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Bendamustine Hydrochloride - API Standards 
    [catalogue_number] => PA 02 07000
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 394.72
    [form] => C16H22Cl3N3O2
    [cas] => 3543-75-7
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PA 02 07000

Bendamustine Hydrochloride - API Standards


  • Catalogue No.:PA 02 07000

  • CAS :

    3543-75-7

  • Molecular Formula : C16H22Cl3N3O2

  • Molecular Weight : 394.72

stdClass Object
(
    [pname] => Bendamustine Methyl Ester
    [catalogue_number] => PA 02 07510
    [category_ids] => ,75,78,70,82,
    [chemical_name] => 
    [weight] => 372.29
    [form] => C17H23Cl2N3O2
    [cas] => 109882-25-9
    [pslug] => 109882-25-9-bendamustine-methyl-ester-pa0207510
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PA 02 07510

Bendamustine Methyl Ester


  • Catalogue No.:PA 02 07510

  • CAS :

    109882-25-9

  • Molecular Formula : C17H23Cl2N3O2

  • Molecular Weight : 372.29

stdClass Object
(
    [pname] => Bendamustine Ethyl Ester
    [catalogue_number] => PA 02 07520
    [category_ids] => ,70,71,75,78,79,82,
    [chemical_name] => 
    [weight] => 386.32
    [form] => C18H25Cl2N3O2
    [cas] => 87475-54-5
    [pslug] => 87475-54-5-bendamustine-ethyl-ester-pa0207520
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PA 02 07520

Bendamustine Ethyl Ester


  • Catalogue No.:PA 02 07520

  • CAS :

    87475-54-5

  • Molecular Formula : C18H25Cl2N3O2

  • Molecular Weight : 386.32

stdClass Object
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    [pname] => Bendamustine Isopropyl Ester
    [catalogue_number] => PA 02 07530
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 400.34
    [form] => C19H27Cl2N3O2
    [cas] => 1313020-25-5
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PA 02 07530

Bendamustine Isopropyl Ester


  • Catalogue No.:PA 02 07530

  • CAS :

    1313020-25-5

  • Molecular Formula : C19H27Cl2N3O2

  • Molecular Weight : 400.34

stdClass Object
(
    [pname] => Dihydroxy Bendamustine
    [catalogue_number] => PA 02 07540
    [category_ids] => ,70,71,75,78,79,82,
    [chemical_name] => 
    [weight] => 321.37
    [form] => C16H23N3O4
    [cas] => 109882-30-6
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PA 02 07540

Dihydroxy Bendamustine


  • Catalogue No.:PA 02 07540

  • CAS :

    109882-30-6

  • Molecular Formula : C16H23N3O4

  • Molecular Weight : 321.37

stdClass Object
(
    [pname] => 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
    [catalogue_number] => PA 02 07600
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 381.9
    [form] => C19H28ClN3O3
    [cas] => 1797008-41-3
    [pslug] => 1797008-41-3-5-2-chloroethyl-2-hydroxyethyl-amino-1-methyl-1h-benzimidazole-2-butanoic-acid-1-methylethyl-ester-pa0207600
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PA 02 07600

5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester


  • Catalogue No.:PA 02 07600

  • CAS :

    1797008-41-3

  • Molecular Formula : C19H28ClN3O3

  • Molecular Weight : 381.9

stdClass Object
(
    [pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07610
    [category_ids] => ,70,71,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 353.87
    [form] => C16H20ClN3O2S
    [cas] => 191939-34-1
    [pslug] => 191939-34-1-4-6-2-chloroethyl-3-methyl-3-6-7-8-tetrahydroimidazo-4-5-5-6-benzo-1-2-b-1-4-thiazin-2-yl-butanoic-acid-pa0207610
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PA 02 07610

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07610

  • CAS :

    191939-34-1

  • Molecular Formula : C16H20ClN3O2S

  • Molecular Weight : 353.87

stdClass Object
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    [pname] => Deschloroethyl Bendamustine
    [catalogue_number] => PA 02 07680
    [category_ids] => ,70,78,80,82,98,
    [chemical_name] => 
    [weight] => 295.76
    [form] => C14H18ClN3O2
    [cas] => 1219709-86-0
    [pslug] => 1219709-86-0-deschloroethyl-bendamustine-pa0207680
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PA 02 07680

Deschloroethyl Bendamustine


  • Catalogue No.:PA 02 07680

  • CAS :

    1219709-86-0

  • Molecular Formula : C14H18ClN3O2

  • Molecular Weight : 295.76

stdClass Object
(
    [pname] => Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07690
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 335.4
    [form] => C17H25N3O4
    [cas] => 109882-31-7
    [pslug] => 109882-31-7-methyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207690
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PA 02 07690

Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07690

  • CAS :

    109882-31-7

  • Molecular Formula : C17H25N3O4

  • Molecular Weight : 335.4

stdClass Object
(
    [pname] => 2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07700
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 666.81
    [form] => C35H50N6O7
    [cas] => NA
    [pslug] => 2-2-hydroxyethyl-2-4-isopropoxy-4-oxobutyl-1-methyl-1h-benzo-d-imidazol-5-yl-amino-ethyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207700
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PA 02 07700

2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07700

  • CAS :

    NA

  • Molecular Formula : C35H50N6O7

  • Molecular Weight : 666.81

stdClass Object
(
    [pname] => Bendamustine Chloro Dimer Impurity
    [catalogue_number] => PA 02 07710
    [category_ids] => ,70,71,75,78,79,82,
    [chemical_name] => 
    [weight] => 680.06
    [form] => C32H41Cl3N6O4
    [cas] => 1228551-91-4
    [pslug] => 1228551-91-4-bendamustine-chloro-dimer-impurity-pa0207710
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PA 02 07710

Bendamustine Chloro Dimer Impurity


  • Catalogue No.:PA 02 07710

  • CAS :

    1228551-91-4

  • Molecular Formula : C32H41Cl3N6O4

  • Molecular Weight : 680.06

stdClass Object
(
    [pname] => 4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07720
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 291.35
    [form] => C15H21N3O3
    [cas] => NA
    [pslug] => 4-5-2-hydroxyethyl-methyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa0207720
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PA 02 07720

4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07720

  • CAS :

    NA

  • Molecular Formula : C15H21N3O3

  • Molecular Weight : 291.35

stdClass Object
(
    [pname] => Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07730
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 319.4
    [form] => C17H25N3O3
    [cas] => NA
    [pslug] => isopropyl-4-5-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207730
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PA 02 07730

Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07730

  • CAS :

    NA

  • Molecular Formula : C17H25N3O3

  • Molecular Weight : 319.4

stdClass Object
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    [pname] => Bendamustine Deschloro Dimer Impurity
    [catalogue_number] => PA 02 07740
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 624.73
    [form] =>  C32H44N6O7
    [cas] => 1391052-61-1
    [pslug] => 1391052-61-1-bendamustine-deschloro-dimer-impurity-pa0207740
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PA 02 07740

Bendamustine Deschloro Dimer Impurity


  • Catalogue No.:PA 02 07740

  • CAS :

    1391052-61-1

  • Molecular Formula : C32H44N6O7

  • Molecular Weight : 624.73

stdClass Object
(
    [pname] => Bendamustine Dimer 2'-Allyl Ester
    [catalogue_number] => PA 02 07750
    [category_ids] => ,79,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 720.13
    [form] => C35H45Cl3N6O4
    [cas] => NA
    [pslug] => bendamustine-dimer-2-allyl-ester-pa0207750
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PA 02 07750

Bendamustine Dimer 2'-Allyl Ester


  • Catalogue No.:PA 02 07750

  • CAS :

    NA

  • Molecular Formula : C35H45Cl3N6O4

  • Molecular Weight : 720.13

stdClass Object
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    [pname] => 4-Chlorobenzene-1,3-diamine
    [catalogue_number] => PA 02 07780
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 142.59
    [form] => C6H7ClN2
    [cas] => 5131-60-2
    [pslug] => 5131-60-2-4-chlorobenzene-1-3-diamine-pa0207780
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PA 02 07780

4-Chlorobenzene-1,3-diamine


  • Catalogue No.:PA 02 07780

  • CAS :

    5131-60-2

  • Molecular Formula : C6H7ClN2

  • Molecular Weight : 142.59

stdClass Object
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    [pname] => N1-Methylbenzene-1,2,4-triamine
    [catalogue_number] => PA 02 07790
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 137.19
    [form] => C7H11N3
    [cas] => 60651-29-8
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PA 02 07790

N1-Methylbenzene-1,2,4-triamine


  • Catalogue No.:PA 02 07790

  • CAS :

    60651-29-8

  • Molecular Formula : C7H11N3

  • Molecular Weight : 137.19

stdClass Object
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    [pname] => Bendamustine Dihydroxy
    [catalogue_number] => PA 02 07810
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 357.84
    [form] => C16H24ClN3O4
    [cas] => 109882-29-3
    [pslug] => 109882-29-3-bendamustine-dihydroxy-pa0207810
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PA 02 07810

Bendamustine Dihydroxy


  • Catalogue No.:PA 02 07810

  • CAS :

    109882-29-3

  • Molecular Formula : C16H24ClN3O4

  • Molecular Weight : 357.84

stdClass Object
(
    [pname] => Bendamustine Ether  Hydrochloride Impurity
    [catalogue_number] => PA 02 07820
    [category_ids] => ,82,80,78,70,
    [chemical_name] => 
    [weight] => 339.82
    [form] => C16H22ClN3O3
    [cas] => 2173004-95-8
    [pslug] => 2173004-95-8-bendamustine-ether-hydrochloride-impurity-pa0207820
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PA 02 07820

Bendamustine Ether Hydrochloride Impurity


  • Catalogue No.:PA 02 07820

  • CAS :

    2173004-95-8

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

stdClass Object
(
    [pname] => Bendamustine Mannitol Ester
    [catalogue_number] => PA 02 07840
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 522.42
    [form] => C22H33Cl2N3O7
    [cas] => 1869075-89-7
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PA 02 07840

Bendamustine Mannitol Ester


  • Catalogue No.:PA 02 07840

  • CAS :

    1869075-89-7

  • Molecular Formula : C22H33Cl2N3O7

  • Molecular Weight : 522.42

stdClass Object
(
    [pname] => 5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid
    [catalogue_number] => PA 02 07850
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 374.26
    [form] => C16H21Cl2N3O3
    [cas] => 1138238-08-0
    [pslug] => 1138238-08-0-5-bis-2-chloroethyl-amino-gamma-hydroxy-1-methyl-1h-benzimidazole-2-butanoic-acid-pa0207850
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PA 02 07850

5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid


  • Catalogue No.:PA 02 07850

  • CAS :

    1138238-08-0

  • Molecular Formula : C16H21Cl2N3O3

  • Molecular Weight : 374.26

stdClass Object
(
    [pname] => N-Desmethylbendamustine
    [catalogue_number] => PA 02 07860
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 344.24
    [form] => C15H19Cl2N3O2
    [cas] => 41515-13-3
    [pslug] => 41515-13-3-n-desmethylbendamustine-pa0207860
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PA 02 07860

N-Desmethylbendamustine


  • Catalogue No.:PA 02 07860

  • CAS :

    41515-13-3

  • Molecular Formula : C15H19Cl2N3O2

  • Molecular Weight : 344.24

stdClass Object
(
    [pname] => 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 0071001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 263.25
    [form] => C12H13N3O4
    [cas] => 31349-48-1
    [pslug] => 31349-48-1-4-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa020071001
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PA 02 0071001

4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 0071001

  • CAS :

    31349-48-1

  • Molecular Formula : C12H13N3O4

  • Molecular Weight : 263.25

stdClass Object
(
    [pname] => N-Methyl-2,4-dinitroaniline
    [catalogue_number] => PA 02 0071002
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 197.15
    [form] => C7H7N3O4
    [cas] => 2044-88-4
    [pslug] => 2044-88-4-n-methyl-2-4-dinitroaniline-pa020071002
    [latest_product] => 0
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PA 02 0071002

N-Methyl-2,4-dinitroaniline


  • Catalogue No.:PA 02 0071002

  • CAS :

    2044-88-4

  • Molecular Formula : C7H7N3O4

  • Molecular Weight : 197.15

stdClass Object
(
    [pname] => [1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester
    [catalogue_number] => PA 02 07830
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 349.43
    [form] => C18H27N3O4
    [cas] => 3543-74-6
    [pslug] => 3543-74-6-1-methyl-5-bis-2-hydroxyethyl-aminobenzimidazolyl-2-butanoic-acid-ethyl-ester-pa0207830
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PA 02 07830

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester


  • Catalogue No.:PA 02 07830

  • CAS :

    3543-74-6

  • Molecular Formula : C18H27N3O4

  • Molecular Weight : 349.43

stdClass Object
(
    [pname] => Bendamustine Ether Impurity
    [catalogue_number] => PA 02 0071003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 303.36
    [form] => C16H21N3O3
    [cas] => 1228552-02-0
    [pslug] => 1228552-02-0-bendamustine-ether-impurity-pa020071003
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PA 02 0071003

Bendamustine Ether Impurity


  • Catalogue No.:PA 02 0071003

  • CAS :

    1228552-02-0

  • Molecular Formula : C16H21N3O3

  • Molecular Weight : 303.36

stdClass Object
(
    [pname] => Bendamustine Dideschloroethyl Acid Hydrochloride
    [catalogue_number] => PA 02 0071004
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 269.73
    [form] => C12H16ClN3O2
    [cas] => 1179363-38-2
    [pslug] => 1179363-38-2-bendamustine-dideschloroethyl-acid-hydrochloride-pa020071004
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PA 02 0071004

Bendamustine Dideschloroethyl Acid Hydrochloride


  • Catalogue No.:PA 02 0071004

  • CAS :

    1179363-38-2

  • Molecular Formula : C12H16ClN3O2

  • Molecular Weight : 269.73