bendamustine hydrochloride
An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Bendamustine Hydrochloride
[catalogue_number] => PA 02 07000
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 394.72
[form] => C16H22Cl3N3O2
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Bendamustine Hydrochloride
Catalogue No.:PA 02 07000
Molecular Formula : C16H22Cl3N3O2
Molecular Weight : 394.72
stdClass Object
(
[pname] => Bendamustine Methyl Ester
[catalogue_number] => PA 02 07510
[category_ids] => ,75,78,70,82,
[chemical_name] =>
[weight] => 372.29
[form] => C17H23Cl2N3O2
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Bendamustine Methyl Ester
Catalogue No.:PA 02 07510
Molecular Formula : C17H23Cl2N3O2
Molecular Weight : 372.29
stdClass Object
(
[pname] => Bendamustine Isopropyl Ester
[catalogue_number] => PA 02 07530
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 400.34
[form] => C19H27Cl2N3O2
[cas] => 1313020-25-5
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Bendamustine Isopropyl Ester
Catalogue No.:PA 02 07530
Molecular Formula : C19H27Cl2N3O2
Molecular Weight : 400.34
stdClass Object
(
[pname] => Dihydroxy Bendamustine
[catalogue_number] => PA 02 07540
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[chemical_name] =>
[weight] => 321.37
[form] => C16H23N3O4
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Catalogue No.:PA 02 07540
Molecular Formula : C16H23N3O4
Molecular Weight : 321.37
stdClass Object
(
[pname] => 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
[catalogue_number] => PA 02 07600
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[chemical_name] =>
[weight] => 381.9
[form] => C19H28ClN3O3
[cas] => 1797008-41-3
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5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
stdClass Object
(
[pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
[catalogue_number] => PA 02 07610
[category_ids] => ,70,71,75,76,78,80,82,
[chemical_name] =>
[weight] => 353.87
[form] => C16H20ClN3O2S
[cas] => 191939-34-1
[pslug] => 191939-34-1-4-6-2-chloroethyl-3-methyl-3-6-7-8-tetrahydroimidazo-4-5-5-6-benzo-1-2-b-1-4-thiazin-2-yl-butanoic-acid-pa0207610
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4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
Catalogue No.:PA 02 07610
Molecular Formula : C16H20ClN3O2S
Molecular Weight : 353.87
stdClass Object
(
[pname] => Deschloroethyl Bendamustine
[catalogue_number] => PA 02 07680
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[chemical_name] =>
[weight] => 295.76
[form] => C14H18ClN3O2
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Deschloroethyl Bendamustine
Catalogue No.:PA 02 07680
Molecular Formula : C14H18ClN3O2
Molecular Weight : 295.76
stdClass Object
(
[pname] => Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
[catalogue_number] => PA 02 07690
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[chemical_name] =>
[weight] => 335.4
[form] => C17H25N3O4
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Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
stdClass Object
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[pname] => 2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
[catalogue_number] => PA 02 07700
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[chemical_name] =>
[weight] => 666.81
[form] => C35H50N6O7
[cas] => NA
[pslug] => 2-2-hydroxyethyl-2-4-isopropoxy-4-oxobutyl-1-methyl-1h-benzo-d-imidazol-5-yl-amino-ethyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207700
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2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
Catalogue No.:PA 02 07700
Molecular Formula : C35H50N6O7
Molecular Weight : 666.81
stdClass Object
(
[pname] => Bendamustine Chloro Dimer Impurity
[catalogue_number] => PA 02 07710
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[chemical_name] =>
[weight] => 680.06
[form] => C32H41Cl3N6O4
[cas] => 1228551-91-4
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Bendamustine Chloro Dimer Impurity
Catalogue No.:PA 02 07710
Molecular Formula : C32H41Cl3N6O4
Molecular Weight : 680.06
stdClass Object
(
[pname] => 4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
[catalogue_number] => PA 02 07720
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[chemical_name] =>
[weight] => 291.35
[form] => C15H21N3O3
[cas] => NA
[pslug] => 4-5-2-hydroxyethyl-methyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa0207720
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4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 07720
Molecular Formula : C15H21N3O3
Molecular Weight : 291.35
stdClass Object
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[pname] => Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
[catalogue_number] => PA 02 07730
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[weight] => 319.4
[form] => C17H25N3O3
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Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
stdClass Object
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[pname] => Bendamustine Deschloro Dimer Impurity
[catalogue_number] => PA 02 07740
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 624.73
[form] => C32H44N6O7
[cas] => 1391052-61-1
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Bendamustine Deschloro Dimer Impurity
Catalogue No.:PA 02 07740
Molecular Formula : C32H44N6O7
Molecular Weight : 624.73
stdClass Object
(
[pname] => Bendamustine Dimer 2'-Allyl Ester
[catalogue_number] => PA 02 07750
[category_ids] => ,79,71,75,78,70,82,
[chemical_name] =>
[weight] => 720.13
[form] => C35H45Cl3N6O4
[cas] => NA
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Bendamustine Dimer 2'-Allyl Ester
Catalogue No.:PA 02 07750
Molecular Formula : C35H45Cl3N6O4
Molecular Weight : 720.13
stdClass Object
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[pname] => 4-Chlorobenzene-1,3-diamine
[catalogue_number] => PA 02 07780
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 142.59
[form] => C6H7ClN2
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4-Chlorobenzene-1,3-diamine
Catalogue No.:PA 02 07780
Molecular Formula : C6H7ClN2
Molecular Weight : 142.59
stdClass Object
(
[pname] => N1-Methylbenzene-1,2,4-triamine
[catalogue_number] => PA 02 07790
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 137.19
[form] => C7H11N3
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N1-Methylbenzene-1,2,4-triamine
Catalogue No.:PA 02 07790
Molecular Formula : C7H11N3
Molecular Weight : 137.19
stdClass Object
(
[pname] => Bendamustine Dihydroxy
[catalogue_number] => PA 02 07810
[category_ids] => ,70,78,80,82,
[chemical_name] =>
[weight] => 357.84
[form] => C16H24ClN3O4
[cas] => 109882-29-3
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Catalogue No.:PA 02 07810
Molecular Formula : C16H24ClN3O4
Molecular Weight : 357.84
stdClass Object
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[pname] => Bendamustine Ether Hydrochloride Impurity
[catalogue_number] => PA 02 07820
[category_ids] => ,82,80,78,70,
[chemical_name] =>
[weight] => 339.82
[form] => C16H22ClN3O3
[cas] => 2173004-95-8
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Bendamustine Ether Hydrochloride Impurity
Catalogue No.:PA 02 07820
Molecular Formula : C16H22ClN3O3
Molecular Weight : 339.82
stdClass Object
(
[pname] => Bendamustine Mannitol Ester
[catalogue_number] => PA 02 07840
[category_ids] => ,70,78,80,82,
[chemical_name] =>
[weight] => 522.42
[form] => C22H33Cl2N3O7
[cas] => 1869075-89-7
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Bendamustine Mannitol Ester
Catalogue No.:PA 02 07840
Molecular Formula : C22H33Cl2N3O7
Molecular Weight : 522.42
stdClass Object
(
[pname] => 5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid
[catalogue_number] => PA 02 07850
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[chemical_name] =>
[weight] => 374.26
[form] => C16H21Cl2N3O3
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5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid
Catalogue No.:PA 02 07850
Molecular Formula : C16H21Cl2N3O3
Molecular Weight : 374.26
stdClass Object
(
[pname] => N-Desmethylbendamustine
[catalogue_number] => PA 02 07860
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 344.24
[form] => C15H19Cl2N3O2
[cas] => 41515-13-3
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Catalogue No.:PA 02 07860
Molecular Formula : C15H19Cl2N3O2
Molecular Weight : 344.24
stdClass Object
(
[pname] => 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
[catalogue_number] => PA 02 0071001
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[chemical_name] =>
[weight] => 263.25
[form] => C12H13N3O4
[cas] => 31349-48-1
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4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 0071001
Molecular Formula : C12H13N3O4
Molecular Weight : 263.25
stdClass Object
(
[pname] => N-Methyl-2,4-dinitroaniline
[catalogue_number] => PA 02 0071002
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 197.15
[form] => C7H7N3O4
[cas] => 2044-88-4
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N-Methyl-2,4-dinitroaniline
Catalogue No.:PA 02 0071002
Molecular Formula : C7H7N3O4
Molecular Weight : 197.15
stdClass Object
(
[pname] => Bendamustine Ether Impurity
[catalogue_number] => PA 02 0071003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 303.36
[form] => C16H21N3O3
[cas] => 1228552-02-0
[pslug] => 1228552-02-0-bendamustine-ether-impurity-pa020071003
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Bendamustine Ether Impurity
Catalogue No.:PA 02 0071003
Molecular Formula : C16H21N3O3
Molecular Weight : 303.36
stdClass Object
(
[pname] => Bendamustine Dideschloroethyl Acid Hydrochloride
[catalogue_number] => PA 02 0071004
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 269.73
[form] => C12H16ClN3O2
[cas] => 1179363-38-2
[pslug] => 1179363-38-2-bendamustine-dideschloroethyl-acid-hydrochloride-pa020071004
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Bendamustine Dideschloroethyl Acid Hydrochloride
Catalogue No.:PA 02 0071004
Molecular Formula : C12H16ClN3O2
Molecular Weight : 269.73
