Bictegravir-impurities | Pharmaffiliates

Bictegravir

Bictegravir (INN, BIC, formerly known as GS-9883) is an antiviral drug of the integrase inhibitor class that was structurally derived from an earlier compound dolutegravir by scientists at Gilead Sciences. Reference standards of Bictegravir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => (S)-3,9-Dihydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
    [catalogue_number] => PA 02 1911000
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 467.4
    [form] => C21H20F3N3O6
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PA 02 1911000

(S)-3,9-Dihydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide


  • Catalogue No.:PA 02 1911000

  • CAS :

    NA

  • Molecular Formula : C21H20F3N3O6

  • Molecular Weight : 467.4

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    [pname] => (R)-3,9-Dihydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
    [catalogue_number] => PA 02 1911001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 467.4
    [form] => C21H20F3N3O6
    [cas] => NA
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PA 02 1911001

(R)-3,9-Dihydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide


  • Catalogue No.:PA 02 1911001

  • CAS :

    NA

  • Molecular Formula : C21H20F3N3O6

  • Molecular Weight : 467.4

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    [pname] => (2R,5S)-8-Hydroxy-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine 6,12-dioxide
    [catalogue_number] => PA 02 1911002
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 481.38
    [form] => C21H18F3N3O7
    [cas] => NA
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PA 02 1911002

(2R,5S)-8-Hydroxy-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine 6,12-dioxide


  • Catalogue No.:PA 02 1911002

  • CAS :

    NA

  • Molecular Formula : C21H18F3N3O7

  • Molecular Weight : 481.38

stdClass Object
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    [pname] => Bictegravir - API Standards 
    [catalogue_number] => PA 02 1910000
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    [chemical_name] => 
    [weight] => 449.39
    [form] => C21H18F3N3O5
    [cas] => 1611493-60-7
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PA 02 1910000

Bictegravir - API Standards


  • Catalogue No.:PA 02 1910000

  • CAS :

    1611493-60-7

  • Molecular Formula : C21H18F3N3O5

  • Molecular Weight : 449.39

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    [pname] => (2S,5R,13aS)-8-Hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911003
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    [weight] => 449.39
    [form] => C21H18F3N3O5
    [cas] => 1616340-12-5
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PA 02 1911003

(2S,5R,13aS)-8-Hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911003

  • CAS :

    1616340-12-5

  • Molecular Formula : C21H18F3N3O5

  • Molecular Weight : 449.39

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    [catalogue_number] => PA 02 1911004
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    [weight] => 449.39
    [form] => C21H18F3N3O5
    [cas] => 1846582-14-6
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PA 02 1911004

(2R,5R,13aR)-8-Hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911004

  • CAS :

    1846582-14-6

  • Molecular Formula : C21H18F3N3O5

  • Molecular Weight : 449.39

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    [pname] => (2R,5S,13aR)-8-Methoxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911005
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    [chemical_name] => 
    [weight] => 463.41
    [form] => C22H20F3N3O5
    [cas] => 1616340-94-3
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PA 02 1911005

(2R,5S,13aR)-8-Methoxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911005

  • CAS :

    1616340-94-3

  • Molecular Formula : C22H20F3N3O5

  • Molecular Weight : 463.41

stdClass Object
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    [pname] => (2R,5S,13aR)-N-(2,4-Difluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 431.4
    [form] => C21H19F2N3O5
    [cas] => 1611493-56-1
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PA 02 1911006

(2R,5S,13aR)-N-(2,4-Difluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911006

  • CAS :

    1611493-56-1

  • Molecular Formula : C21H19F2N3O5

  • Molecular Weight : 431.4

stdClass Object
(
    [pname] => (2S,5R,13aS)-N-(2-Fluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911007
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    [weight] => 413.41
    [form] => C21H20FN3O5
    [cas] => 1616339-90-2
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PA 02 1911007

(2S,5R,13aS)-N-(2-Fluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911007

  • CAS :

    1616339-90-2

  • Molecular Formula : C21H20FN3O5

  • Molecular Weight : 413.41

stdClass Object
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    [pname] => (2S,5R,13aS)-N-(4-Fluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 413.41
    [form] => C21H20FN3O5
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PA 02 1911008

(2S,5R,13aS)-N-(4-Fluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911008

  • CAS :

    1616339-82-2

  • Molecular Formula : C21H20FN3O5

  • Molecular Weight : 413.41

stdClass Object
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    [pname] => (2S,5R,13aS)-N-(2,6-Difluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
    [catalogue_number] => PA 02 1911009
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    [weight] => 431.4
    [form] => C21H19F2N3O5
    [cas] => 1616340-13-6
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PA 02 1911009

(2S,5R,13aS)-N-(2,6-Difluorobenzyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide


  • Catalogue No.:PA 02 1911009

  • CAS :

    1616340-13-6

  • Molecular Formula : C21H19F2N3O5

  • Molecular Weight : 431.4

stdClass Object
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    [pname] => (2S,3S,4S,5R,6S)-6-(((2R,5S,13aR)-7,9-Dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepin-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
    [catalogue_number] => PA 02 1911011
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    [chemical_name] => 
    [weight] => 625.51
    [form] => C27H26F3N3O11
    [cas] => 2365156-60-9
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PA 02 1911011

(2S,3S,4S,5R,6S)-6-(((2R,5S,13aR)-7,9-Dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepin-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid


  • Catalogue No.:PA 02 1911011

  • CAS :

    2365156-60-9

  • Molecular Formula : C27H26F3N3O11

  • Molecular Weight : 625.51

stdClass Object
(
    [pname] => Bictegravir-13C-15N-d2
    [catalogue_number] => PA STI 089238
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 453.38
    [form] => C2013CH16D2F3N215NO5
    [cas] => NA
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PA STI 089238

Bictegravir-13C-15N-d2


  • Catalogue No.:PA STI 089238

  • CAS :

    NA

  • Molecular Formula : C2013CH16D2F3N215NO5

  • Molecular Weight : 453.38

stdClass Object
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    [pname] => 9-Hydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
    [catalogue_number] => PA 02 1911012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 449.39
    [form] => C21H18F3N3O5
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PA 02 1911012

9-Hydroxy-2-((1S,3R)-3-hydroxycyclopentyl)-1,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide


  • Catalogue No.:PA 02 1911012

  • CAS :

    NA

  • Molecular Formula : C21H18F3N3O5

  • Molecular Weight : 449.39

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    [pname] => (2R,5S,13aR)-8-Hydroxy-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine 6,12-dioxide
    [catalogue_number] => PA 02 1911013
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 481.38
    [form] => C21H18F3N3O7
    [cas] => NA
    [pslug] => 2r-5s-13ar-8-hydroxy-7-9-dioxo-10-2-4-6-trifluorobenzyl-carbamoyl-2-3-4-5-7-9-13-13a-octahydro-2-5-methanopyrido-1-2-4-5-pyrazino-2-1-b-1-3-oxazepine-6-12-dioxide-pa021911013
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PA 02 1911013

(2R,5S,13aR)-8-Hydroxy-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine 6,12-dioxide


  • Catalogue No.:PA 02 1911013

  • CAS :

    NA

  • Molecular Formula : C21H18F3N3O7

  • Molecular Weight : 481.38