carfilzomib
Fine chemicals
- Carfilzomib is derived from epoxomicin, a natural product that was shown by the laboratory of Craig Crews at Yale University to inhibit the proteasome. It is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.. Reference standards of Carfilzomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[pname] => (S)-2-Amino-N-methoxy-N,4-dimethylpentanamide
[catalogue_number] => PA 30 0631076
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[weight] => 174.24
[form] => C8H18N2O2
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(S)-2-Amino-N-methoxy-N,4-dimethylpentanamide
Catalogue No.:PA 30 0631076
Molecular Formula : C8H18N2O2
Molecular Weight : 174.24
stdClass Object
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[catalogue_number] => PA 30 0631077
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[weight] => 739.91
[form] => C39H57N5O9
[cas] => NA
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4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide
Catalogue No.:PA 30 0631077
Molecular Formula : C39H57N5O9
Molecular Weight : 739.91
stdClass Object
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[pname] => 4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
[catalogue_number] => PA 30 0631078
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[weight] => 719.92
[form] => C40H57N5O7
[cas] => NA
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4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Catalogue No.:PA 30 0631078
Molecular Formula : C40H57N5O7
Molecular Weight : 719.92
stdClass Object
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[pname] => ((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid
[catalogue_number] => PA 30 0631079
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[weight] => 394.42
[form] => C19H26N2O7
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((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid
Catalogue No.:PA 30 0631079
Molecular Formula : C19H26N2O7
Molecular Weight : 394.42
stdClass Object
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[pname] => 2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid
[catalogue_number] => PA 30 0631080
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[chemical_name] =>
[weight] => 276.29
[form] => C14H16N2O4
[cas] => NA
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2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid
Catalogue No.:PA 30 0631080
Molecular Formula : C14H16N2O4
Molecular Weight : 276.29
stdClass Object
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[pname] => ((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid
[catalogue_number] => PA 30 0631081
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[weight] => 294.31
[form] => C14H18N2O5
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((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid
Catalogue No.:PA 30 0631081
Molecular Formula : C14H18N2O5
Molecular Weight : 294.31
stdClass Object
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[pname] => N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine
[catalogue_number] => PA 30 0631082
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[weight] => 294.31
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N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine
Catalogue No.:PA 30 0631082
Molecular Formula : C14H18N2O5
Molecular Weight : 294.31
stdClass Object
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[pname] => (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid
[catalogue_number] => PA 30 0631083
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[weight] => 440.54
[form] => C25H32N2O5
[cas] => NA
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(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid
Catalogue No.:PA 30 0631083
Molecular Formula : C25H32N2O5
Molecular Weight : 440.54
stdClass Object
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[catalogue_number] => PA 30 0631084
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[weight] => 719.92
[form] => C40H57N5O7
[cas] => NA
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(2S)-4-Methyl-N-(1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Catalogue No.:PA 30 0631084
Molecular Formula : C40H57N5O7
Molecular Weight : 719.92
stdClass Object
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[pname] => (2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
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[weight] => 719.92
[form] => C40H57N5O7
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(2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Catalogue No.:PA 30 0631085
Molecular Formula : C40H57N5O7
Molecular Weight : 719.92
stdClass Object
(
[pname] => Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate
[catalogue_number] => PA 30 0631086
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 629.8
[form] => C37H47N3O6
[cas] => 868540-15-2
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Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate