carfilzomib

Fine chemicals - Carfilzomib is derived from epoxomicin, a natural product that was shown by the laboratory of Craig Crews at Yale University to inhibit the proteasome. It is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.. Reference standards of Carfilzomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => (S)-2-Amino-N-methoxy-N,4-dimethylpentanamide
    [catalogue_number] => PA 30 0631076
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 174.24
    [form] => C8H18N2O2
    [cas] => 102837-29-6
    [pslug] => 102837-29-6-s-2-amino-n-methoxy-n-4-dimethylpentanamide-pa300631076
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PA 30 0631076
PA 30 0631076

(S)-2-Amino-N-methoxy-N,4-dimethylpentanamide


  • Catalogue No.:PA 30 0631076

  • CAS :

    102837-29-6

  • Molecular Formula : C8H18N2O2

  • Molecular Weight : 174.24

stdClass Object
(
    [pname] => 4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide
    [catalogue_number] => PA 30 0631077
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 739.91
    [form] => C39H57N5O9
    [cas] => NA
    [pslug] => 4-methyl-2-2-2-morpholinoacetamido-4-phenylbutanamido-n-1-oxo-3-phenyl-1-1-2-2-trihydroxy-6-methyl-3-oxoheptan-4-yl-amino-propan-2-yl-pentanamide-pa300631077
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PA 30 0631077
PA 30 0631077

4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide


  • Catalogue No.:PA 30 0631077

  • CAS :

    NA

  • Molecular Formula : C39H57N5O9

  • Molecular Weight : 739.91

stdClass Object
(
    [pname] => 4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631078
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
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PA 30 0631078
PA 30 0631078

4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631078

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => ((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid
    [catalogue_number] => PA 30 0631079
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 394.42
    [form] => C19H26N2O7
    [cas] => NA
    [pslug] => s-2-tert-butoxycarbonyl-amino-4-phenylbutanoyl-l-aspartic-acid-pa300631079
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PA 30 0631079
PA 30 0631079

((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631079

  • CAS :

    NA

  • Molecular Formula : C19H26N2O7

  • Molecular Weight : 394.42

stdClass Object
(
    [pname] => 2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid
    [catalogue_number] => PA 30 0631080
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 276.29
    [form] => C14H16N2O4
    [cas] => NA
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PA 30 0631080
PA 30 0631080

2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid


  • Catalogue No.:PA 30 0631080

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

stdClass Object
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    [pname] => ((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid
    [catalogue_number] => PA 30 0631081
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
    [cas] => 3066865-52-6
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PA 30 0631081
PA 30 0631081

((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631081

  • CAS :

    3066865-52-6

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

stdClass Object
(
    [pname] => N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine
    [catalogue_number] => PA 30 0631082
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
    [cas] => NA
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PA 30 0631082
PA 30 0631082

N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine


  • Catalogue No.:PA 30 0631082

  • CAS :

    NA

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

stdClass Object
(
    [pname] => (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid
    [catalogue_number] => PA 30 0631083
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 440.54
    [form] => C25H32N2O5
    [cas] => NA
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PA 30 0631083
PA 30 0631083

(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid


  • Catalogue No.:PA 30 0631083

  • CAS :

    NA

  • Molecular Formula : C25H32N2O5

  • Molecular Weight : 440.54

stdClass Object
(
    [pname] => (2S)-4-Methyl-N-(1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631084
    [category_ids] => ,82,80,78,71,70,
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    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
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PA 30 0631084
PA 30 0631084

(2S)-4-Methyl-N-(1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631084

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => (2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
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    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
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PA 30 0631085
PA 30 0631085

(2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631085

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate
    [catalogue_number] => PA 30 0631086
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 629.8
    [form] => C37H47N3O6
    [cas] => 868540-15-2
    [pslug] => 868540-15-2-benzyl-s-2-tert-butoxycarbonyl-amino-4-phenylbutanoyl-l-leucyl-l-phenylalaninate-pa300631086
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PA 30 0631086
PA 30 0631086

Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate


  • Catalogue No.:PA 30 0631086

  • CAS :

    868540-15-2

  • Molecular Formula : C37H47N3O6

  • Molecular Weight : 629.8

Details
stdClass Object
(
    [pname] => 4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide
    [catalogue_number] => PA 30 0631077
    [category_ids] => ,82,80,78,71,70,
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    [weight] => 739.91
    [form] => C39H57N5O9
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PA 30 0631077
PA 30 0631077

4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide


  • Catalogue No.:PA 30 0631077

  • CAS :

    NA

  • Molecular Formula : C39H57N5O9

  • Molecular Weight : 739.91

stdClass Object
(
    [pname] => 4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631078
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
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PA 30 0631078
PA 30 0631078

4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631078

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => ((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid
    [catalogue_number] => PA 30 0631079
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 394.42
    [form] => C19H26N2O7
    [cas] => NA
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PA 30 0631079
PA 30 0631079

((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631079

  • CAS :

    NA

  • Molecular Formula : C19H26N2O7

  • Molecular Weight : 394.42

stdClass Object
(
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    [chemical_name] => 
    [weight] => 276.29
    [form] => C14H16N2O4
    [cas] => NA
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PA 30 0631080
PA 30 0631080

2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid


  • Catalogue No.:PA 30 0631080

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

stdClass Object
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    [pname] => ((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid
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    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
    [cas] => 3066865-52-6
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PA 30 0631081
PA 30 0631081

((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631081

  • CAS :

    3066865-52-6

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

stdClass Object
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    [catalogue_number] => PA 30 0631082
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
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PA 30 0631082
PA 30 0631082

N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine


  • Catalogue No.:PA 30 0631082

  • CAS :

    NA

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

stdClass Object
(
    [pname] => (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid
    [catalogue_number] => PA 30 0631083
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 440.54
    [form] => C25H32N2O5
    [cas] => NA
    [pslug] => s-2-s-2-tert-butoxycarbonyl-amino-4-phenylbutanamido-4-phenylbutanoic-acid-pa300631083
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PA 30 0631083
PA 30 0631083

(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid


  • Catalogue No.:PA 30 0631083

  • CAS :

    NA

  • Molecular Formula : C25H32N2O5

  • Molecular Weight : 440.54

stdClass Object
(
    [pname] => (2S)-4-Methyl-N-(1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631084
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
    [pslug] => 2s-4-methyl-n-1-s-4-methyl-1-r-2-methyloxiran-2-yl-1-oxopentan-2-yl-amino-1-oxo-3-phenylpropan-2-yl-2-s-2-2-morpholinoacetamido-4-phenylbutanamido-pentanamide-pa300631084
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PA 30 0631084
PA 30 0631084

(2S)-4-Methyl-N-(1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631084

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => (2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631085
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
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PA 30 0631085
PA 30 0631085

(2S)-4-Methyl-N-(1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631085

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

stdClass Object
(
    [pname] => Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate
    [catalogue_number] => PA 30 0631086
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 629.8
    [form] => C37H47N3O6
    [cas] => 868540-15-2
    [pslug] => 868540-15-2-benzyl-s-2-tert-butoxycarbonyl-amino-4-phenylbutanoyl-l-leucyl-l-phenylalaninate-pa300631086
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PA 30 0631086
PA 30 0631086

Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate


  • Catalogue No.:PA 30 0631086

  • CAS :

    868540-15-2

  • Molecular Formula : C37H47N3O6

  • Molecular Weight : 629.8

pharmaffiliates
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