dolutegravir
Dolutegravir is a HIV-1 intergrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell.. Reference standards of Dolutegravir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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Dolutegravir - API Standards
Catalogue No.:PA 04 95000
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
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[pname] => Dolutegravir Sodium Salt - API Standards
[catalogue_number] => PA 04 95600
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[weight] => 441.36
[form] => C20H18F2N3NaO5
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Dolutegravir Sodium Salt - API Standards
Catalogue No.:PA 04 95600
Molecular Formula : C20H18F2N3NaO5
Molecular Weight : 441.36
stdClass Object
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[pname] => 4-Fluoro Dolutegravir
[catalogue_number] => PA 04 95510
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[weight] => 401.39
[form] => C20H20FN3O5
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Catalogue No.:PA 04 95510
Molecular Formula : C20H20FN3O5
Molecular Weight : 401.39
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Catalogue No.:PA 04 95520
Molecular Formula : C20H20FN3O5
Molecular Weight : 401.39
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[catalogue_number] => PA 04 95540
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Catalogue No.:PA 04 95540
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
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(4S,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalogue No.:PA 04 95550
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
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(4R,12aS)-N-(2,4-Difluorobenzyl)-7-((2,4-difluorobenzyl)amino)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
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[pname] => Bis(2,4-difluorobenzyl)amine
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Bis(2,4-difluorobenzyl)amine
Catalogue No.:PA 04 95580
Molecular Formula : C14H11F4N
Molecular Weight : 269.24
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[pname] => (R)-7-(2,4-Difluorobenzylcarbamoyl)-2-(4-(2,4-difluorobenzylcarbamoyloxy)butan-2-yl)-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-9-olate Sodium Salt
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[weight] => 610.49
[form] => C28H23F4N4NaO6
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(R)-7-(2,4-Difluorobenzylcarbamoyl)-2-(4-(2,4-difluorobenzylcarbamoyloxy)butan-2-yl)-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-9-olate Sodium Salt
Catalogue No.:PA 04 95590
Molecular Formula : C28H23F4N4NaO6
Molecular Weight : 610.49
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[pname] => Dolutegravir-d3
[catalogue_number] => PA STI 036152
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[form] => C20H16D3F2N3O5
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Catalogue No.:PA STI 036152
Molecular Formula : C20H16D3F2N3O5
Molecular Weight : 422.40
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Catalogue No.:PA 04 0951000
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
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[catalogue_number] => PA 04 0951002
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[weight] => 447.44
[form] => C22H23F2N3O5
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(R)-N-(2,4-Difluorobenzyl)-9-ethoxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
Catalogue No.:PA 04 0951002
Molecular Formula : C22H23F2N3O5
Molecular Weight : 447.44
stdClass Object
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[pname] => Sodium (4S,12aS)-9-((2,4-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate
[catalogue_number] => PA 04 95610
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[weight] => 441.37
[form] => C20H18F2N3NaO5
[cas] => NA
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Sodium (4S,12aS)-9-((2,4-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate
Catalogue No.:PA 04 95610
Molecular Formula : C20H18F2N3NaO5
Molecular Weight : 441.37
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[pname] => Dolutegravir SR Isomer
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Catalogue No.:PA 04 95620
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
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(S)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
Catalogue No.:PA 04 95630
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
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[weight] => 421.4
[form] => C20H21F2N3O5
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(R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,3,4,8-tetrahydro-1H-pyrido[1,2-a]pyrazine-7-carboxamide
stdClass Object
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[catalogue_number] => PA 04 0951003
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[weight] => 267.22
[form] => C14H9F4N
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(E)-N-(2,4-Difluorobenzylidene)-1-(2,4-difluorophenyl)methanamine
Catalogue No.:PA 04 0951003
Molecular Formula : C14H9F4N
Molecular Weight : 267.22
stdClass Object
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[pname] => (R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
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[weight] => 308.29
[form] => C14H16N2O6
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(R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
Catalogue No.:PA 04 0951004
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
stdClass Object
(
[pname] => O-Methyl ent-Dolutegravir
[catalogue_number] => PA 04 0951007
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[chemical_name] =>
[weight] => 433.41
[form] => C21H21F2N3O5
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O-Methyl ent-Dolutegravir
Catalogue No.:PA 04 0951007
Molecular Formula : C21H21F2N3O5
Molecular Weight : 433.41
stdClass Object
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[pname] => (4S,12aR)-N-(5-Benzyl-2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
[catalogue_number] => PA 04 0951009
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[chemical_name] =>
[weight] => 509.51
[form] => C27H25F2N3O5
[cas] => NA
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(4S,12aR)-N-(5-Benzyl-2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951009
Molecular Formula : C27H25F2N3O5
Molecular Weight : 509.51
stdClass Object
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1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic acid methyl ester
Catalogue No.:PA 04 0951011
Molecular Formula : C17H19NO6
Molecular Weight : 333.34
stdClass Object
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[weight] => 304.35
[form] => C20H16O3
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2-[(1E)-2-Phenylethenyl]-3-(phenylmethoxy)-4H-pyran-4-one
Catalogue No.:PA 04 0951012
Molecular Formula : C20H16O3
Molecular Weight : 304.35
stdClass Object
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[weight] => 319.31
[form] => C16H17NO6
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1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic acid
Catalogue No.:PA 04 0951013
Molecular Formula : C16H17NO6
Molecular Weight : 319.31
stdClass Object
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[weight] => 246.22
[form] => C13H10O5
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4-Oxo-3-[(Phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
Catalogue No.:PA 04 0951010
Molecular Formula : C13H10O5
Molecular Weight : 246.22
stdClass Object
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[weight] => 293.28
[form] => C13H15N3O5
[cas] => 1485081-26-2
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(4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951014
Molecular Formula : C13H15N3O5
Molecular Weight : 293.28
stdClass Object
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[weight] => 294.26
[form] => C13H14N2O6
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(3S,7R)-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxylic acid
Catalogue No.:PA 04 0951015
Molecular Formula : C13H14N2O6
Molecular Weight : 294.26
stdClass Object
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[weight] => 509.51
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(4R,12aS)-N-(5-benzyl-2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951016
Molecular Formula : C27H25F2N3O5
Molecular Weight : 509.51
stdClass Object
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(4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951017
Molecular Formula : C27H25F2N3O5
Molecular Weight : 509.51
stdClass Object
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[pname] => O-Methyl Dolutegravir
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[weight] => 433.41
[form] => C21H21F2N3O5
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Catalogue No.:PA 04 0951018
Molecular Formula : C21H21F2N3O5
Molecular Weight : 433.41
stdClass Object
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[weight] => 447.44
[form] => C22H23F2N3O5
[cas] => 1802141-49-6
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(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951019
Molecular Formula : C22H23F2N3O5
Molecular Weight : 447.44
stdClass Object
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[pname] => 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid
[catalogue_number] => PA 04 0951020
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[weight] => 215.16
[form] => C9H7F2NO3
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2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid
Catalogue No.:PA 04 0951020
Molecular Formula : C9H7F2NO3
Molecular Weight : 215.16
stdClass Object
(
[pname] => (R)-N-(2,4-difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
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[weight] => 419.38
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[cas] => 1973402-05-9
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(R)-N-(2,4-difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
Catalogue No.:PA 04 0951021
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
stdClass Object
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[pname] => N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
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N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
Catalogue No.:PA 04 0951022
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
stdClass Object
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[pname] => Desdifluoro Dolutegravir Sodium Salt
[catalogue_number] => PA 04 0951023
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[weight] => 405.39
[form] => C20H20N3NaO5
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Desdifluoro Dolutegravir Sodium Salt
Catalogue No.:PA 04 0951023
Molecular Formula : C20H20N3NaO5
Molecular Weight : 405.39
stdClass Object
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(4R,12aR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid
Catalogue No.:PA 04 0951024
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
stdClass Object
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[weight] => 269.21
[form] => C11H11NO7
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5-Methoxy-6-(methoxycarbonyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-3-carboxylic acid
Catalogue No.:PA 04 0951026
Molecular Formula : C11H11NO7
Molecular Weight : 269.21
stdClass Object
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[weight] => 423.38
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[cas] => NA
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Sodium (4R,12aS)-9-((4-fluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate
Catalogue No.:PA 04 0951027
Molecular Formula : C20H19FN3NaO5
Molecular Weight : 423.38
stdClass Object
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(4R,12aS)-N-Benzyl-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951028
Molecular Formula : C21H23N3O5
Molecular Weight : 397.43
stdClass Object
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[catalogue_number] => PA STI 089160
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Catalogue No.:PA STI 089160
Molecular Formula : C20H15D4F2N3O5
Molecular Weight : 423.41
stdClass Object
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Sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-9-olate
Catalogue No.:PA 04 0951029
Molecular Formula : C20H18F2N3NaO5
Molecular Weight : 441.37
stdClass Object
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(4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalogue No.:PA 04 0951030
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
stdClass Object
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N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951031
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
stdClass Object
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[form] => C12H15NO8
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1-(2,2-Dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylic Acid
Catalogue No.:PA 04 0951032
Molecular Formula : C12H15NO8
Molecular Weight : 301.25
stdClass Object
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Sodium (4R,12aS)-9-((2-fluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate
Catalogue No.:PA 04 0951033
Molecular Formula : C20H19FN3NaO5
Molecular Weight : 423.38
stdClass Object
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[weight] => 308.29
[form] => C14H16N2O6
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(4S,12aR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalogue No.:PA 04 0951034
Molecular Formula : C14H16N2O6
Molecular Weight : 308.29
stdClass Object
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[catalogue_number] => PA 04 0951035
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[weight] => 595.51
[form] => C26H27F2N3O11
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Dolutegravir O-beta-D-Glucuronide
Catalogue No.:PA 04 0951035
Molecular Formula : C26H27F2N3O11
Molecular Weight : 595.51
stdClass Object
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[weight] => 297.26
[form] => C13H15NO7
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5-Ethoxy-6-(ethoxycarbonyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-3-carboxylic Acid
Catalogue No.:PA 04 0951036
Molecular Formula : C13H15NO7
Molecular Weight : 297.26
stdClass Object
(
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[weight] => 322.32
[form] => C15H18N2O6
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(4R,12aR)-7-Ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalogue No.:PA 04 0951037
Molecular Formula : C15H18N2O6
Molecular Weight : 322.32
stdClass Object
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[pname] => Dolutegravir Isopropyl Analouge
[catalogue_number] => PA 04 0951038
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[weight] => 461.47
[form] => C23H25F2N3O5
[cas] => NA
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Dolutegravir Isopropyl Analouge
Catalogue No.:PA 04 0951038
Molecular Formula : C23H25F2N3O5
Molecular Weight : 461.47
stdClass Object
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[pname] => (R)-3-(7-((2,4-Difluorobenzyl)carbamoyl)-9-hydroxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-2-yl)butyl (2,4-difluorobenzyl)carbamate
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[weight] => 588.52
[form] => C28H24F4N4O6
[cas] => 2244161-73-5
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(R)-3-(7-((2,4-Difluorobenzyl)carbamoyl)-9-hydroxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazin-2-yl)butyl (2,4-difluorobenzyl)carbamate
Catalogue No.:PA 04 0951039
Molecular Formula : C28H24F4N4O6
Molecular Weight : 588.52
stdClass Object
(
[pname] => Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate
[catalogue_number] => PA 04 0951040
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[weight] => 322.32
[form] => C15H18N2O6
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Ethyl (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate
Catalogue No.:PA 04 0951040
Molecular Formula : C15H18N2O6
Molecular Weight : 322.32
stdClass Object
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[pname] => (R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
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[weight] => 294.26
[form] => C13H14N2O6
[cas] => NA
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(R)-9-Hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
Catalogue No.:PA 04 0951041
Molecular Formula : C13H14N2O6
Molecular Weight : 294.26
stdClass Object
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[catalogue_number] => PA 04 0951042
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[weight] => 312.27
[form] => C15H12F4N2O
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1,3-Bis(2,4-difluorobenzyl)urea
Catalogue No.:PA 04 0951042
Molecular Formula : C15H12F4N2O
Molecular Weight : 312.27
stdClass Object
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[pname] => O-Methyl Dolutegravir Ring Open Chain
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[weight] => 433.41
[form] => C21H21F2N3O5
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O-Methyl Dolutegravir Ring Open Chain
Catalogue No.:PA 04 0951043
Molecular Formula : C21H21F2N3O5
Molecular Weight : 433.41
stdClass Object
(
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[weight] => 433.41
[form] => C21H21F2N3O5
[cas] => 2968897-85-8
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rel-(4R,12aR)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalogue No.:PA 04 0951044
Molecular Formula : C21H21F2N3O5
Molecular Weight : 433.41