Larotrectinib-impurities | Pharmaffiliates

Larotrectinib

Larotrectinib (tradename Vitrakvi) is a drug for the treatment of cancer.It is an inhibitor of tropomyosin kinase receptors TrkA, TrkB, and TrkC. It was discovered by Array BioPharma and licensed to Loxo Oncology in 2013. Reference standards of Larotrectinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Larotrectinib - API Standards 
    [catalogue_number] => PA 12 1480000
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 428.44
    [form] => C21H22F2N6O2
    [cas] => 1223403-58-4
    [pslug] => 1223403-58-4-larotrectinib-api-pa121480000
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 1480000

Larotrectinib - API Standards


  • Catalogue No.:PA 12 1480000

  • CAS :

    1223403-58-4

  • Molecular Formula : C21H22F2N6O2

  • Molecular Weight : 428.44

stdClass Object
(
    [pname] => (S)-N-(5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
    [catalogue_number] => PA 12 1481000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 281.7
    [form] => C11H12ClN5O2
    [cas] => 2226370-52-9
    [pslug] => 2226370-52-9-s-n-5-chloropyrazolo-1-5-a-pyrimidin-3-yl-3-hydroxypyrrolidine-1-carboxamide-pa121481000
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 1481000

(S)-N-(5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide


  • Catalogue No.:PA 12 1481000

  • CAS :

    2226370-52-9

  • Molecular Formula : C11H12ClN5O2

  • Molecular Weight : 281.7

stdClass Object
(
    [pname] => (S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione
    [catalogue_number] => PA 12 1481002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 205.21
    [form] => C11H11NO3
    [cas] => 101469-91-4
    [pslug] => 101469-91-4-s-1-benzyl-3-hydroxypyrrolidine-2-5-dione-pa121481002
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 1481002

(S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione


  • Catalogue No.:PA 12 1481002

  • CAS :

    101469-91-4

  • Molecular Formula : C11H11NO3

  • Molecular Weight : 205.21

stdClass Object
(
    [pname] => (S)-1-benzylpyrrolidin-3-ol
    [catalogue_number] => PA 12 1481001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 177.25
    [form] => C11H15NO
    [cas] => 101385-90-4
    [pslug] => 101385-90-4-s-1-benzylpyrrolidin-3-ol-pa121481001
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 12 1481001

(S)-1-benzylpyrrolidin-3-ol


  • Catalogue No.:PA 12 1481001

  • CAS :

    101385-90-4

  • Molecular Formula : C11H15NO

  • Molecular Weight : 177.25