Ruxolitinib-impurities | Pharmaffiliates

ruxolitinib

Ruxolitinib is used to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body's ability to produce blood cells. Reference standards of Ruxolitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Ruxolitinib - API Standards 
    [catalogue_number] => PA 18 82000
    [category_ids] => ,80,69,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941678-49-5
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PA 18 82000

Ruxolitinib - API Standards


  • Catalogue No.:PA 18 82000

  • CAS :

    941678-49-5

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
(
    [pname] => 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 18 0821002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 315.45
    [form] => C15H21N5OSi
    [cas] => 941685-27-4
    [pslug] => 941685-27-4-4-1h-pyrazol-4-yl-7-2-trimethylsilyl-ethoxy-methyl-7h-pyrrolo-2-3-d-pyrimidine-pa180821002
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PA 18 0821002

4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 18 0821002

  • CAS :

    941685-27-4

  • Molecular Formula : C15H21N5OSi

  • Molecular Weight : 315.45

20% OFF
stdClass Object
(
    [pname] => rac-Ruxolitinib-13C,15N2
    [catalogue_number] => PA STI 078620
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 309.34
    [form] => C1613CH18N415N2
    [cas] => NA
    [pslug] => rac-ruxolitinib-13c-15n2-pasti078620
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PA STI 078620

rac-Ruxolitinib-13C,15N2


  • Catalogue No.:PA STI 078620

  • CAS :

    NA

  • Molecular Formula : C1613CH18N415N2

  • Molecular Weight : 309.34

stdClass Object
(
    [pname] => rac-Ruxolitinib-d8
    [catalogue_number] => PA STI 078630
    [category_ids] => ,80,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 314.41
    [form] => C17H10D8N6
    [cas] => NA
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PA STI 078630

rac-Ruxolitinib-d8


  • Catalogue No.:PA STI 078630

  • CAS :

    NA

  • Molecular Formula : C17H10D8N6

  • Molecular Weight : 314.41

stdClass Object
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    [pname] => Ruxolitinib-amide
    [catalogue_number] => PA 18 0821000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 324.39
    [form] => C17H20N6O
    [cas] => 1911644-32-0
    [pslug] => 1911644-32-0-ruxolitinib-amide-pa180821000
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PA 18 0821000

Ruxolitinib-amide


  • Catalogue No.:PA 18 0821000

  • CAS :

    1911644-32-0

  • Molecular Formula : C17H20N6O

  • Molecular Weight : 324.39

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    [pname] => (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanamide
    [catalogue_number] => PA 18 0821001
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    [weight] => 324.39
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    [cas] => 2102675-42-1
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PA 18 0821001

(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanamide


  • Catalogue No.:PA 18 0821001

  • CAS :

    2102675-42-1

  • Molecular Formula : C17H20N6O

  • Molecular Weight : 324.39

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    [pname] => 3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 436.64
    [form] => C23H32N6OSi
    [cas] => 941685-39-8
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PA 18 0821003

3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821003

  • CAS :

    941685-39-8

  • Molecular Formula : C23H32N6OSi

  • Molecular Weight : 436.64

stdClass Object
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    [pname] => (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
    [catalogue_number] => PA 18 0821004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 306.37
    [form] => C17H18N6
    [cas] => 941685-37-6
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PA 18 0821004

(S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile


  • Catalogue No.:PA 18 0821004

  • CAS :

    941685-37-6

  • Molecular Formula : C17H18N6

  • Molecular Weight : 306.37

stdClass Object
(
    [pname] => (R)-4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid
    [catalogue_number] => PA 18 0821005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 326.36
    [form] => C16H18N6O2
    [cas] => 2606144-44-7
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PA 18 0821005

(R)-4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid


  • Catalogue No.:PA 18 0821005

  • CAS :

    2606144-44-7

  • Molecular Formula : C16H18N6O2

  • Molecular Weight : 326.36

stdClass Object
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    [pname] => (R)-3-(4-(6-Amino-5-formylpyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
    [catalogue_number] => PA 18 0821006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 310.36
    [form] => C16H18N6O
    [cas] => 2606144-45-8
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PA 18 0821006

(R)-3-(4-(6-Amino-5-formylpyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile


  • Catalogue No.:PA 18 0821006

  • CAS :

    2606144-45-8

  • Molecular Formula : C16H18N6O

  • Molecular Weight : 310.36

stdClass Object
(
    [pname] => 3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid
    [catalogue_number] => PA 18 0821007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 325.37
    [form] => C17H19N5O2
    [cas] => NA
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PA 18 0821007

3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid


  • Catalogue No.:PA 18 0821007

  • CAS :

    NA

  • Molecular Formula : C17H19N5O2

  • Molecular Weight : 325.37

stdClass Object
(
    [pname] => (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid
    [catalogue_number] => PA 18 0821008
    [category_ids] => ,75,76,78,70,82,
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    [weight] => 325.37
    [form] => C17H19N5O2
    [cas] => 2102675-40-9
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PA 18 0821008

(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid


  • Catalogue No.:PA 18 0821008

  • CAS :

    2102675-40-9

  • Molecular Formula : C17H19N5O2

  • Molecular Weight : 325.37

stdClass Object
(
    [pname] => (R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
    [catalogue_number] => PA 18 0821009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 268.16
    [form] => C11H14BrN3
    [cas] => 1146629-83-5
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PA 18 0821009

(R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile


  • Catalogue No.:PA 18 0821009

  • CAS :

    1146629-83-5

  • Molecular Formula : C11H14BrN3

  • Molecular Weight : 268.16

stdClass Object
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    [pname] => (R)-3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821010
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 335.37
    [form] => C17H17N7O
    [cas] => NA
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PA 18 0821010

(R)-3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821010

  • CAS :

    NA

  • Molecular Formula : C17H17N7O

  • Molecular Weight : 335.37

stdClass Object
(
    [pname] => (3R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxycyclopentyl)propanenitrile
    [catalogue_number] => PA 18 0821011
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 322.37
    [form] => C17H18N6O
    [cas] => 1809535-63-4
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PA 18 0821011

(3R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxycyclopentyl)propanenitrile


  • Catalogue No.:PA 18 0821011

  • CAS :

    1809535-63-4

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

stdClass Object
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    [pname] => (R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 1-oxide
    [catalogue_number] => PA 18 0821012
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    [weight] => 322.37
    [form] => C17H18N6O
    [cas] => NA
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PA 18 0821012

(R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 1-oxide


  • Catalogue No.:PA 18 0821012

  • CAS :

    NA

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

stdClass Object
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    [pname] => (R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 3-oxide
    [catalogue_number] => PA 18 0821013
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PA 18 0821013

(R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 3-oxide


  • Catalogue No.:PA 18 0821013

  • CAS :

    NA

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

stdClass Object
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    [pname] => Methyl (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoate
    [catalogue_number] => PA 18 0821014
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    [weight] => 339.4
    [form] => C18H21N5O2
    [cas] => NA
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PA 18 0821014

Methyl (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoate


  • Catalogue No.:PA 18 0821014

  • CAS :

    NA

  • Molecular Formula : C18H21N5O2

  • Molecular Weight : 339.4

stdClass Object
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    [pname] => Ruxolitinib Hydroxy Pyrimidine Impurity
    [catalogue_number] => PA 18 0821015
    [category_ids] => ,76,78,70,80,69,82,
    [chemical_name] => 
    [weight] => 336.4
    [form] => C18H20N6O
    [cas] => NA
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PA 18 0821015

Ruxolitinib Hydroxy Pyrimidine Impurity


  • Catalogue No.:PA 18 0821015

  • CAS :

    NA

  • Molecular Formula : C18H20N6O

  • Molecular Weight : 336.4

stdClass Object
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    [pname] => (R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821016
    [category_ids] => ,76,78,70,80,69,82,
    [chemical_name] => 
    [weight] => 436.64
    [form] => C23H32N6OSi
    [cas] => 941685-40-1
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PA 18 0821016

(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821016

  • CAS :

    941685-40-1

  • Molecular Formula : C23H32N6OSi

  • Molecular Weight : 436.64

stdClass Object
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    [pname] => Ruxolitinib Acetamide Impurity
    [catalogue_number] => PA 18 0821017
    [category_ids] => ,80,69,71,78,82,117,76,
    [chemical_name] => 
    [weight] => 377.45
    [form] => C20H23N7O
    [cas] => NA
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PA 18 0821017

Ruxolitinib Acetamide Impurity


  • Catalogue No.:PA 18 0821017

  • CAS :

    NA

  • Molecular Formula : C20H23N7O

  • Molecular Weight : 377.45

stdClass Object
(
    [pname] => 7-Nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-ol
    [catalogue_number] => PA 18 0821018
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 164.12
    [form] => C6H4N4O2
    [cas] => NA
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PA 18 0821018

7-Nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-ol


  • Catalogue No.:PA 18 0821018

  • CAS :

    NA

  • Molecular Formula : C6H4N4O2

  • Molecular Weight : 164.12

stdClass Object
(
    [pname] => 4-(1-Nitroso-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
    [catalogue_number] => PA 18 0821019
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 344.45
    [form] => C15H20N6O2Si
    [cas] => NA
    [pslug] => 4-1-nitroso-1h-pyrazol-4-yl-7-2-trimethylsilyl-ethoxy-methyl-7h-pyrrolo-2-3-d-pyrimidine-pa180821019
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PA 18 0821019

4-(1-Nitroso-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine


  • Catalogue No.:PA 18 0821019

  • CAS :

    NA

  • Molecular Formula : C15H20N6O2Si

  • Molecular Weight : 344.45

stdClass Object
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    [pname] => Ruxolitinib N-Methanol
    [catalogue_number] => PA 18 0821020
    [category_ids] => ,76,78,70,80,69,82,
    [chemical_name] => 
    [weight] => 336.4
    [form] => C18H20N6O
    [cas] => 1236033-03-6
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PA 18 0821020

Ruxolitinib N-Methanol


  • Catalogue No.:PA 18 0821020

  • CAS :

    1236033-03-6

  • Molecular Formula : C18H20N6O

  • Molecular Weight : 336.4

stdClass Object
(
    [pname] => 3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide
    [catalogue_number] => PA 18 0821021
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 353.39
    [form] => C17H19N7O2
    [cas] => NA
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PA 18 0821021

3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide


  • Catalogue No.:PA 18 0821021

  • CAS :

    NA

  • Molecular Formula : C17H19N7O2

  • Molecular Weight : 353.39

stdClass Object
(
    [pname] => Ruxolitinib M18 Metabolite
    [catalogue_number] => PA 18 0821022
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 322.37
    [form] => C17H18N6O
    [cas] => 1315607-85-2
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PA 18 0821022

Ruxolitinib M18 Metabolite


  • Catalogue No.:PA 18 0821022

  • CAS :

    1315607-85-2

  • Molecular Formula : C17H18N6O

  • Molecular Weight : 322.37

stdClass Object
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    [pname] => (+)-Di-p-anisoyl-D-tartaric Acid
    [catalogue_number] => PA 18 0821023
    [category_ids] => ,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 418.35
    [form] => C20H18O10
    [cas] => 191605-10-4
    [pslug] => 191605-10-4-di-p-anisoyl-d-tartaric-acid-pa180821023
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PA 18 0821023

(+)-Di-p-anisoyl-D-tartaric Acid


  • Catalogue No.:PA 18 0821023

  • CAS :

    191605-10-4

  • Molecular Formula : C20H18O10

  • Molecular Weight : 418.35

stdClass Object
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    [pname] => 3-Cyclopentylacrylonitrile
    [catalogue_number] => PA 18 0821024
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 121.18
    [form] => C8H11N
    [cas] => 591769-05-0
    [pslug] => 591769-05-0-3-cyclopentylacrylonitrile-pa180821024
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PA 18 0821024

3-Cyclopentylacrylonitrile


  • Catalogue No.:PA 18 0821024

  • CAS :

    591769-05-0

  • Molecular Formula : C8H11N

  • Molecular Weight : 121.18

stdClass Object
(
    [pname] => (R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate
    [catalogue_number] => PA 18 0821025
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 794.94
    [form] => C41H46N6O9Si
    [cas] => 1236033-04-7
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PA 18 0821025

(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate


  • Catalogue No.:PA 18 0821025

  • CAS :

    1236033-04-7

  • Molecular Formula : C41H46N6O9Si

  • Molecular Weight : 794.94

stdClass Object
(
    [pname] => 3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821026
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.22
    [form] => C17H26BN3O2
    [cas] => 1153949-38-2
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PA 18 0821026

3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821026

  • CAS :

    1153949-38-2

  • Molecular Formula : C17H26BN3O2

  • Molecular Weight : 315.22

stdClass Object
(
    [pname] => 3-Cyclopentyl-3-(4-(5-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
    [catalogue_number] => PA 18 0821027
    [category_ids] => ,76,78,70,80,69,82,
    [chemical_name] => 
    [weight] => 336.4
    [form] => C18H20N6O
    [cas] => NA
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PA 18 0821027

3-Cyclopentyl-3-(4-(5-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile


  • Catalogue No.:PA 18 0821027

  • CAS :

    NA

  • Molecular Formula : C18H20N6O

  • Molecular Weight : 336.4