sunitinib
An oral anti cancer drug. Works by inhibiting cellular signals by targeting multiple receptor tyrosine kinases (RTKs). Sunitinib is approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) Reference standards of Sunitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Sunitinib - API Standards
Catalogue No.:PA 19 75000
Molecular Formula : C22H27FN4O2
Molecular Weight : 398.47
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(Z)-N-Ethyl-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]- 2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75520
Molecular Formula : C18H18FN3O2
Molecular Weight : 327.35
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[pname] => Sunitinib L-Malate - API Standards
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Sunitinib L-Malate - API Standards
Catalogue No.:PA 19 75530
Molecular Formula : C26H33FN4O7
Molecular Weight : 532.56
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Catalogue No.:PA 19 75540
Molecular Formula : C22H27FN4O3
Molecular Weight : 414.47
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N-[2-(Diethylamino)ethyl]-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75590
Molecular Formula : C14H23N3O2
Molecular Weight : 265.36
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Sunitinib (Mixture of E and Z Isomer)
Catalogue No.:PA 19 75580
Molecular Formula : C22H27FN4O2
Molecular Weight : 398.48
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Catalogue No.:PA 19 75510
Molecular Formula : C20H23FN4O2
Molecular Weight : 370.42
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Catalogue No.:PA 19 75570
Molecular Formula : C22H27FN4O2
Molecular Weight : 398.47
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N-Boc-N-desethyl Sunitinib-d5
Catalogue No.:PA STI 013910
Molecular Formula : C25H26D5FN4O4
Molecular Weight : 475.57
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Catalogue No.:PA STI 027510
Molecular Formula : C20H18D5FN4O2
Molecular Weight : 375.45
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N,N-Didesethyl Sunitinib-d4 Hydrochloride
Catalogue No.:PA STI 030950
Molecular Formula : C18H16D4ClFN4O2
Molecular Weight : 382.85
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Catalogue No.:PA STI 080680
Molecular Formula : C22H17D10FN4O2
Molecular Weight : 408.54
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Catalogue No.:PA STI 080690
Molecular Formula : C22H23D4FN4O2
Molecular Weight : 402.50
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N,N-Didesethyl Sunitinib Hydrochloride
Catalogue No.:PA 19 75610
Molecular Formula : C18H20ClFN4O2
Molecular Weight : 378.83
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Catalogue No.:PA 19 75620
Molecular Formula : C22H25FN4O3
Molecular Weight : 412.47
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N-Boc-N,N-didesethyl Sunitinib
Catalogue No.:PA 19 75630
Molecular Formula : C23H27FN4O4
Molecular Weight : 442.49
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Catalogue No.:PA 19 75640
Molecular Formula : C20H23FN4O2
Molecular Weight : 370.43
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N-Boc-N-desethyl Sunitinib
Catalogue No.:PA 19 75650
Molecular Formula : C25H31FN4O4
Molecular Weight : 470.55
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(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxyethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75660
Molecular Formula : C18H18FN3O3
Molecular Weight : 343.36
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Catalogue No.:PA 19 75670
Molecular Formula : C28H35FN4O8
Molecular Weight : 574.61
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(Z)-3-((3,5-Dimethyl-4-(pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-5-fluoroindolin-2-one
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(Z)-N-(2-(Ethylamino)ethyl)-5-((6-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75690
Molecular Formula : C20H23FN4O2
Molecular Weight : 370.43
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(E)-N-(2-(Diethylamino)ethyl)-5-((4-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75700
Molecular Formula : C22H27FN4O2
Molecular Weight : 398.48
stdClass Object
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Catalogue No.:PA 19 75710
Molecular Formula : C23H29FN4O2
Molecular Weight : 412.51
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(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N,N,2,4-tetramethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 75720
Molecular Formula : C18H18FN3O2
Molecular Weight : 327.36
stdClass Object
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Catalogue No.:PA 19 0751000
Molecular Formula : C18H19FN4O2
Molecular Weight : 342.37
stdClass Object
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4-(Ethoxycarbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid
Catalogue No.:PA 19 0751002
Molecular Formula : C10H13NO4
Molecular Weight : 211.22
stdClass Object
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2-(Hydroxymethyl)-4-methyl Sunitinib
Catalogue No.:PA 19 0751003
Molecular Formula : C22H27FN4O3
Molecular Weight : 414.48
stdClass Object
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(Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2-formyl-4-methyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 0751004
Molecular Formula : C22H25FN4O3
Molecular Weight : 412.47
stdClass Object
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N-(4-fluorophenyl)-2-oxoacetamide
Catalogue No.:PA 19 0751005
Molecular Formula : C8H6FNO2
Molecular Weight : 167.14
stdClass Object
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5,5'-Difluoro-3,3'-dihydroxy-[3,3'-biindoline]-2,2'-dione
Catalogue No.:PA 19 0751006
Molecular Formula : C16H10F2N2O4
Molecular Weight : 332.26
stdClass Object
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4-Amino-2-bromocyclohexan-1-one
Catalogue No.:PA 19 0751007
Molecular Formula : C6H10BrNO
Molecular Weight : 192.06
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2,4-Dimethyl-1H-pyrrole-3-carbaldehyde
Catalogue No.:PA 19 0751008
Molecular Formula : C7H9NO
Molecular Weight : 123.16
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3,5-Dimethyl-1H-pyrrole-2,4-dicarbaldehyde
Catalogue No.:PA 19 0751009
Molecular Formula : C8H9NO2
Molecular Weight : 151.17
stdClass Object
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[weight] => 179.15
[form] => C8H6FN3O
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5-Fluoro-1H-indole-2,3-dione 3-Hydrazone
Catalogue No.:PA 19 0751010
Molecular Formula : C8H6FN3O
Molecular Weight : 179.15
stdClass Object
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[weight] => 282.26
[form] => C13H10N6O2
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Bis((1H-benzo[d][1,2,3]triazol-1-yl)oxy)methane
Catalogue No.:PA 19 0751011
Molecular Formula : C13H10N6O2
Molecular Weight : 282.26
stdClass Object
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[weight] => 166.18
[form] => C8H10N2O2
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5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 0751012
Molecular Formula : C8H10N2O2
Molecular Weight : 166.18
stdClass Object
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[weight] => 316.26
[form] => C16H10F2N2O3
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5,5'-Difluoro-3-hydroxy-[3,3'-biindoline]-2,2'-dione
Catalogue No.:PA 19 0751014
Molecular Formula : C16H10F2N2O3
Molecular Weight : 316.26
stdClass Object
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Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid
Catalogue No.:PA 19 0751015
Molecular Formula : C16H13FN2O3
Molecular Weight : 300.29
stdClass Object
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3-((3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-5-fluoroindolin-2-one
Catalogue No.:PA 19 0751016
Molecular Formula : C15H13FN2O
Molecular Weight : 256.28
stdClass Object
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(Z)-N-(3-(Dimethylamino)propyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 0751017
Molecular Formula : C21H25FN4O2
Molecular Weight : 384.46
stdClass Object
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N-Ethyl-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 0751018
Molecular Formula : C18H18FN3O2
Molecular Weight : 327.36
stdClass Object
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[weight] => 399.43
[form] => C20H22FN5O3
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N-Nitroso N-Desethyl Sunitinib
Catalogue No.:PA 19 0751019
Molecular Formula : C20H22FN5O3
Molecular Weight : 399.43
stdClass Object
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[weight] => 427.48
[form] => C22H26FN5O3
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(Z)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1-nitroso-1H-pyrrole-3-carboxamide
Catalogue No.:PA 19 0751020
Molecular Formula : C22H26FN5O3
Molecular Weight : 427.48