cabozantinib
Cabozantinib is used in two forms. A capsule form is used since 2012 to treat medullary thyroid cancer and a tablet form is used since 2016 as a second line treatment for renal cell carcinoma.. Reference standards of Cabozantinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
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[pname] => Cabozantinib
[catalogue_number] => PA 30 62000
[category_ids] => ,79,80,71,78,70,82,89,
[chemical_name] =>
[weight] => 501.51
[form] => C28H24FN3O5
[cas] => 849217-68-1
[pslug] => 849217-68-1-cabozantinib-api-pa3062000
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Catalogue No.:PA 30 62000
Molecular Formula : C28H24FN3O5
Molecular Weight : 501.51
stdClass Object
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[pname] => 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
[catalogue_number] => PA 30 62600
[category_ids] => ,80,79,89,71,
[chemical_name] =>
[weight] => 223.2
[form] => C11H10FNO3
[cas] => 849217-48-7
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1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
stdClass Object
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[pname] => N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
[catalogue_number] => PA 30 62610
[category_ids] => ,80,79,89,71,78,82,70,
[chemical_name] =>
[weight] => 314.31
[form] => C17H15FN2O3
[cas] => 849217-60-3
[pslug] => 849217-60-3-n-4-fluorophenyl-n-4-hydroxyphenyl-cyclopropane-1-1-dicarboxamide-pa3062610
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N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
Catalogue No.:PA 30 62610
Molecular Formula : C17H15FN2O3
Molecular Weight : 314.31
stdClass Object
(
[pname] => Cabozantinib-d4
[catalogue_number] => PA STI 089396
[category_ids] => ,98,79,80,71,78,70,82,89,
[chemical_name] =>
[weight] => 505.54
[form] => C28H20D4FN3O5
[cas] => 1802168-53-1
[pslug] => 1802168-53-1-cabozantinib-d4-pasti089396
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Catalogue No.:PA STI 089396
Molecular Formula : C28H20D4FN3O5
Molecular Weight : 505.54
stdClass Object
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[pname] => N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide
[catalogue_number] => PA 30 0621037
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[chemical_name] =>
[weight] => 519.53
[form] => C28H26FN3O6
[cas] => NA
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N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide
Catalogue No.:PA 30 0621037
Molecular Formula : C28H26FN3O6
Molecular Weight : 519.53
stdClass Object
(
[pname] => (2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid
[catalogue_number] => PA 30 0621038
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[chemical_name] =>
[weight] => 635.6
[form] => C32H30FN3O10
[cas] => NA
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(2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid
stdClass Object
(
[pname] => N,N'-Bis(4-fluorophenyl)oxamide
[catalogue_number] => PA 30 0621040
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[chemical_name] =>
[weight] => 276.24
[form] => C14H10F2N2O2
[cas] => 10197-51-0
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N,N'-Bis(4-fluorophenyl)oxamide
Catalogue No.:PA 30 0621040
Molecular Formula : C14H10F2N2O2
Molecular Weight : 276.24